Patients with dementia with lewy bodies have more impaired quality of life than patients with Alzheimer disease [0.03%]
路易体痴呆患者的生活质量比阿尔茨海默病患者受损更严重
Fredrik Boström,Linus Jönsson,Lennart Minthon et al.
Fredrik Boström et al.
The primary aim of this study was to compare quality of life (QoL) in patients with Dementia with Lewy Bodies (DLB) and patients with Alzheimer disease (AD). The secondary aim of this study was to investigate determinants of QoL in DLB. Thi...
Zoe Arvanitakis,Robert S Wilson,Julia L Bienias et al.
Zoe Arvanitakis et al.
We examined the relation of type 2 diabetes mellitus to parkinsonian signs in older persons. Participants were 1030 women and men (mean age 80.3 y, education 14.5 y, Mini-Mental State Examination 27.9) without dementia or Parkinson disease,...
A 24-week randomized, controlled trial of memantine in patients with moderate-to-severe Alzheimer disease [0.03%]
轻至中度阿尔茨海默型痴呆临床疗效的26周安慰剂对照随机双盲甲磺酸盐研究
Christopher H van Dyck,Pierre N Tariot,Barnett Meyers et al.
Christopher H van Dyck et al.
This study examined the efficacy and safety of memantine monotherapy in patients with moderate-to-severe Alzheimer disease (AD). Patients not receiving a cholinesterase inhibitor (N=350) were randomized to receive memantine (20 mg/d) or pla...
Perception of emotions on happy/sad chimeric faces in Alzheimer disease: relationship with cognitive functions [0.03%]
阿尔茨海默病患者对快乐/悲伤嵌合面部表情的感知与认知功能的关系研究
Simona Luzzi,Massimo Piccirilli,Leandro Provinciali
Simona Luzzi
Aims: To investigate the ability to recognize facial emotions in patients with Alzheimer disease (AD). Happiness and sadness, fundamental emotions that are easily recognized across cultures, were evaluated. Results were f...
Laura A Cushman,Charles J Duffy
Laura A Cushman
Alzheimer disease (AD) is associated with navigational impairments that limit functional independence. We have now examined the role of cognitive and perceptual mechanisms in the navigational impairment of AD to test the hypothesis that men...
Documentation, assessment, and treatment of aggression in patients with newly diagnosed dementia [0.03%]
新诊断痴呆患者的攻击性行为的记录、评估和治疗
Mark E Kunik,Jonathan P Walgama,A Lynn Snow et al.
Mark E Kunik et al.
Practice guidelines recommend a search for underlying biopsychosocial causes and initial use of nonpharmacologic interventions. Using guidelines as a benchmark for standard care, we examined medical records to assess the documentation, asse...
Dementia diagnosis disclosure: a study of patient and caregiver perspectives [0.03%]
痴呆诊断告知：患者和照护者的视角研究
Anna M Byszewski,Frank J Molnar,Faranak Aminzadeh et al.
Anna M Byszewski et al.
This paper reports the findings of a descriptive, exploratory, qualitative study of patient and caregiver perspectives of the disclosure of a dementia diagnosis. Data were collected at 3 points in time: (1) the disclosure meeting, (2) patie...
Symptoms of memory loss as predictors of cognitive impairment?: the use and reliability of memory ratings in a clinic population [0.03%]
记忆力下降的症状能够预测认知损害吗？——临床病人中记忆评估的应用和可靠性分析
Hilary A Archer,Fiona McFarlane,Chris Frost et al.
Hilary A Archer et al.
Background: Symptoms of memory loss are very common with estimated prevalence between 22% and 50% in those older than 65 years of age. Those with symptoms of memory loss and impaired performance on memory tests are at hig...
Impact of patient selection criteria on prevalence estimates and prevalence of diagnosed dementia in a Medicaid population [0.03%]
入组标准对医疗补助项目参保人群中痴呆患病率估算的影响及诊断的痴呆流行病学调查结果
Murtuza F Bharmal,Michael Weiner,Laura P Sands et al.
Murtuza F Bharmal et al.
Objectives: This study estimated the prevalence of diagnosed dementia among Indiana Medicaid beneficiaries in 2004. The dependence of prevalence estimates upon use of several patient selection criteria to identify patient...
Heritability of magnetic resonance imaging (MRI) traits in Alzheimer disease cases and their siblings in the MIRAGE study [0.03%]
MIRAGE研究中阿尔茨海默病患者及其同胞的磁共振成像(MRI)特征遗传度分析
Kathryn L Lunetta,Porat M Erlich,Karen T Cuenco et al.
Kathryn L Lunetta et al.
Magnetic resonance imaging (MRI) traits can serve as more specific measures of degenerative or cerebrovascular brain injury than can be ascertained through personal history, risk factors, clinical signs, or symptoms. They are potentially us...