The cognitive subscale of Alzheimer's Disease Assessment Scale, Chinese version in staging of Alzheimer disease [0.03%]
ADAS-Cog量表在中国阿尔茨海默病患者不同临床分型与分期中的应用研究
Huali Wang,Xin Yu,Shuran Li et al.
Huali Wang et al.
This study was designed to examine the utility of the ADAS-Cog, Chinese version (ADAS-Cog-C) for staging of dementia in Alzheimer disease (AD). A total of 305 patients with AD (199 mild AD and 106 moderate AD) meeting the NINCDS-ADRDA crite...
The Activities of Daily Living Questionnaire: a validation study in patients with dementia [0.03%]
痴呆患者日常生活活动问卷的验证性研究
N Johnson,A Barion,A Rademaker et al.
N Johnson et al.
This study describes the development and validation of the Activities of Daily Living Questionnaire (ADLQ), an informant-based assessment of functional abilities, in patients with probable Alzheimer disease and other forms of dementia. The ...
Comparative Study
Alzheimer disease and associated disorders. 2004 Oct-Dec;18(4):223-30. DOI: 2004
Reliability of monitoring the clinical dementia rating in multicenter clinical trials [0.03%]
临床痴呆评定量表在多中心临床试验中可靠性的研究
Kimberly A Schafer,Rochelle E Tractenberg,Mary Sano et al.
Kimberly A Schafer et al.
Context: The Clinical Dementia Rating (CDR) is quickly becoming a criterion standard in multicenter clinical trials in Alzheimer disease. An abbreviated version, with formal monitoring for consistency across sites and rat...
Richard Camicioli,Lisa Licis
Richard Camicioli
We sought to identify clinical risk factors for falls in people with advanced Alzheimer disease (AD) in a prospective longitudinal observational study set in specialized AD care units. Forty-two patients with probable or possible AD were re...
Hypertension and the rate of cognitive decline in patients with dementia of the Alzheimer type [0.03%]
高血压与阿尔茨海默病型痴呆患者的认知下降速度的关系
Kevin M Bellew,Joseph G Pigeon,Paul E Stang et al.
Kevin M Bellew et al.
Hypertension has been suspected of being associated with Alzheimer disease (AD). To study this problem, a case-control study investigating the association between hypertension and cognitive decline was conducted as a secondary analysis of d...
Meta-Analysis
Alzheimer disease and associated disorders. 2004 Oct-Dec;18(4):208-13. DOI: 2004
Neuropsychological and functional measures of severity in Alzheimer disease, frontotemporal dementia, and semantic dementia [0.03%]
阿尔茨海默病、 frontal temporal lobe dementia以及语义性痴呆的神经心理学和功能评测方法
Howard J Rosen,Jenille M Narvaez,Brad Hallam et al.
Howard J Rosen et al.
Many studies attempting to compare the clinical features in different dementia syndromes have attempted to control for overall disease severity using neuropsychological or functional measures. However, these measures may not give equivalent...
Comparative Study
Alzheimer disease and associated disorders. 2004 Oct-Dec;18(4):202-7. DOI: 2004
Comparisons between global and focal brain atrophy rates in normal aging and Alzheimer disease: Boundary Shift Integral versus tracing of the entorhinal cortex and hippocampus [0.03%]
全局和局部脑萎缩率在正常衰老和阿尔茨海默病中的差异：边界转移积分法与内侧颞叶结构手工勾画的对比研究
Frank Ezekiel,Linda Chao,John Kornak et al.
Frank Ezekiel et al.
The objectives of this study were to (1) compare atrophy rates associated with normal aging and Alzheimer disease (AD) using the semi-automated Boundary Shift Integral (BSI) method and manual tracing of the entorhinal cortex (ERC) and hippo...
Comparative Study
Alzheimer disease and associated disorders. 2004 Oct-Dec;18(4):196-201. DOI: 2004
Correlations between antemortem hippocampal volume and postmortem neuropathology in AD subjects [0.03%]
阿尔茨海默病患者生前海马体积与死后神经病理学的相关性研究
John G Csernansky,Julia Hamstra,Lei Wang et al.
John G Csernansky et al.
Antemortem measures of hippocampal volume have been used to distinguish subjects with and without probable Alzheimer disease (AD). However, relatively little information is available about how well such antemortem measures correlate with po...
Roger M Nitsch
Roger M Nitsch
Optimism regarding the treatment and prevention of Alzheimer disease has begun to replace the attitude of therapeutic nihilism that clouded the field for so many decades. Neurotransmitter-based therapy with AChEls and NMDA receptor antagoni...
Leon J Thal
Leon J Thal