H Zanjani,C E Finch,C Kemper et al.
H Zanjani et al.
The activation of the classical complement (C)-system in early-stage Alzheimer disease (AD) and nondemented aging was examined with immunohistochemistry in subjects assessed by the Clinical Dementia Rating (CDR). Activation (staining for C3...
More culturally sensitive neuropsychological tests (and normative data) needed [0.03%]
亟需更多文化胜任的心理神经学检查(及正常值)
F R Ferraro,Leander R McDonald
F R Ferraro
Helena Chui
Helena Chui
Health-related quality-of-life of care-givers as a predictor of nursing-home placement of patients with dementia [0.03%]
照料者的健康相关生活质量是痴呆患者入住护理机构的预测指标
Josep M Argimon,Esther Limon,Joan Vila et al.
Josep M Argimon et al.
Care-giver health-related quality-of-life (QoL) as a predictor of nursing-home placement of family-member patients with dementia was evaluated (using the SF-36 questionnaire) in 181 care providers (78% females; mean age 63 years) at the sta...
Time for change: the role of nonpharmacological interventions in treating behavior problems in nursing home residents with dementia [0.03%]
行为改变时刻:非药物治疗在护理机构痴呆患者行为问题中的作用
Jiska Cohen-Mansfield,Jacobo E Mintzer
Jiska Cohen-Mansfield
This paper discusses the etiology of behavior problems in dementia and concludes that a substantial portion of such behaviors arise when care does not appropriately address the underlying causes. The needs of persons with dementia are frequ...
Cognition, function, and caregiving time patterns in patients with mild-to-moderate Alzheimer disease: a 12-month analysis [0.03%]
轻中度阿尔茨海默病患者认知、功能和照护时间模式的12个月分析
Howard H Feldman,Bart Van Baelen,Shane M Kavanagh et al.
Howard H Feldman et al.
Placebo data were pooled from two 1-year, randomized, double-blind, placebo-controlled trials of sabeluzole in patients with mild-to-moderate Alzheimer disease (AD). Cognition was assessed using the Alzheimer's Disease Assessment Scale-cogn...
Propranolol for disruptive behaviors in nursing home residents with probable or possible Alzheimer disease: a placebo-controlled study [0.03%]
普洛纳尔ول治疗疑似或可能患有阿尔茨海默病的养老院居民的精神行为症状:一项安慰剂对照研究
Elaine R Peskind,Debby W Tsuang,Lauren T Bonner et al.
Elaine R Peskind et al.
Objective: Enhanced behavioral responsiveness to central nervous system (CNS) norepinephrine (NE) in Alzheimer disease (AD) may contribute to the pathophysiology of disruptive behaviors such as aggression, uncooperativene...
Nick Dunn,Clive Holmes,Mark Mullee
Nick Dunn
Lithium compounds might theoretically play a role in preventing dementia by inhibiting formation both of beta amyloid and hyper phosphorylated tau protein. We carried out a case-control study to assess any possible clinical effects of lithi...
Referral patterns for syndromes associated with frontotemporal lobar degeneration [0.03%]
与 frontal temporal 皮层变性有关的综合症的转诊模式
Tiffany W Chow,John R Hodges,Kate E Dawson et al.
Tiffany W Chow et al.
We compared demographics of subjects diagnosed with frontotemporal degeneration (FTD) at a group of 5 clinics specializing in this non-Alzheimer dementia against those subjects diagnosed at standard Alzheimer disease centers, to determine a...
Brief screening tests for the diagnosis of dementia: comparison with the mini-mental state exam [0.03%]
简易痴呆诊断筛选检查与迷你精神状态检查对照研究
Sandy Kilada,Alyssa Gamaldo,Elizabeth A Grant et al.
Sandy Kilada et al.
Dementia is a common and under-diagnosed problem among the elderly. An accurate screening test would greatly aid the ability of physicians to evaluate dementia and memory problems in clinical practice. We sought to determine whether simple ...