Use of live theater to increase minority participation in Alzheimer disease research [0.03%]
使用现场戏剧促进少数族裔参与阿尔茨海默病研究
Thomas Fritsch,Kathryn Betts Adams,Darlyne Redd et al.
Thomas Fritsch et al.
Recruitment and retention of African Americans into Alzheimer disease (AD) research studies poses challenges owing to long-standing socio-economic and cultural differences, pragmatic difficulties in reaching the African American population,...
A cost effective method of identifying and recruiting persons over 80 free of dementia or mild cognitive impairment [0.03%]
一种有效识别和招募无痴呆症或轻度认知障碍的80岁以上老人的方法
Neill R Graff-Radford,Tanis J Ferman,John A Lucas et al.
Neill R Graff-Radford et al.
For observational or prevention studies, accurately identifying by mail and telephone cognitively normal elderly volunteers would be cost effective. We describe how to recruit cognitively normal sib-pairs over age 80 using commercially avai...
Vascular risk factors for incident Alzheimer disease and vascular dementia: the Cache County study [0.03%]
加舒县研究中阿兹海默症及血管性失智前期的血管性疾病危险因素
Kathleen M Hayden,Peter P Zandi,Constantine G Lyketsos et al.
Kathleen M Hayden et al.
Vascular risk factors for Alzheimer disease (AD) and vascular dementia (VaD) have been evaluated; however, few studies have compared risks by dementia subtypes and sex. We evaluated relationships between cardiovascular risk factors (hyperte...
Word list versus story memory in Alzheimer disease and frontotemporal dementia [0.03%]
阿尔茨海默病和额颞叶痴呆的单词表与故事记忆能力比较研究
Alissa H Wicklund,Nancy Johnson,Alfred Rademaker et al.
Alissa H Wicklund et al.
Memory impairment, characterized by a pattern of rapid forgetting, is the hallmark deficit in Alzheimer's disease (AD). Memory deficits have also been reported in frontotemporal dementia (FTD), and are thought to reflect diminished organiza...
Effects of Alzheimer disease on fronto-parietal brain N-acetyl aspartate and myo-inositol using magnetic resonance spectroscopic imaging [0.03%]
阿尔茨海默病对脑额顶区N-乙酰天门冬氨酸和肌醇的影响的磁共振波谱研究
Xiaoping Zhu,Norbert Schuff,John Kornak et al.
Xiaoping Zhu et al.
Previous magnetic resonance (MR) spectroscopy studies of Alzheimer disease (AD) reporting reduced N-acetyl aspartate (NAA) and increased myo-Inositol (mI) used single voxel techniques, which have limited ability to assess the regional distr...
An association with great implications: vascular pathology and Alzheimer disease [0.03%]
具有重大意义的联系：血管病变与阿尔茨海默病的关系
Alex E Roher,Tyler A Kokjohn,Thomas G Beach
Alex E Roher
Amy R Borenstein,Cathleen I Copenhaver,James A Mortimer
Amy R Borenstein
Research findings obtained over the past 20 years suggest that Alzheimer disease (AD) may have its origins in early life. In this review, we consider the evidence for early-life risk factors for this illness. We propose that risk factors th...
John Hardy,Alan Pittman,Amanda Myers et al.
John Hardy et al.
Neurofibrillary tangles are found in many neurologic diseases. Here we review the unusual characteristics of the MAPT locus, which shows genetic association with many of these diseases and in Caucasian populations, is the largest stretch of...
Neuropathologic correlates of activities of daily living in Alzheimer disease [0.03%]
阿尔茨海默病患者日常生活活动与神经病理的相关性
Gad A Marshall,Lynn A Fairbanks,Sibel Tekin et al.
Gad A Marshall et al.
Functional status, reflected by measures of activities of daily living (ADLs), deteriorates as Alzheimer disease (AD) progresses. Decline in activities of daily living may be mediated by executive and frontal lobe dysfunction. The objective...
Patient- and proxy-reported utility in Alzheimer disease using the EuroQoL [0.03%]
基于EuroQol的阿尔茨海默病患者和代理人的效用评估
Linus Jönsson,Niels Andreasen,Lena Kilander et al.
Linus Jönsson et al.
This study aims to compare patient- and proxy-rated utilities and health-related quality of life from individuals in different stages of Alzheimer disease (AD). Two hundred seventy-two patients and their primary caregivers were enrolled in ...