Rapid Metal -free Macromolecular Coupling via in situ Nitrile Oxide-Activated Alkene Cycloaddition [0.03%]
一种快速的金属-free通过原位硝基氧化物活化的烯烃环加成实现大分子偶联的方法
Michael J Isaacman,Weibin Cui,Luke S Theogarajan
Michael J Isaacman
Nitrile oxide 1,3 dipolar cycloaddition is a simple and powerful coupling methodology. However, the self-dimerization of nitrile oxides has prevented the widespread use of this strategy for macromolecular coupling. By combining an in situ n...
Synthesis and characterization of a multi-arm poly(acrylic acid) star polymer for application in sustained delivery of cisplatin and a nitric oxide prodrug [0.03%]
一种用于递送顺铂和一氧化氮前药的多臂聚丙烯酸星型聚合物的设计、合成及表征研究
Shaofeng Duan,Shuang Cai,Yumei Xie et al.
Shaofeng Duan et al.
Functionalized polymeric nanocarriers have been recognized as drug delivery platforms for delivering therapeutic concentrations of chemotherapies. Of this category, star-shaped multiarm polymers are emerging candidates for targeted delivery...
Strategies Toward Well-Defined Polymer Nanoparticles Inspired by Nature: Chemistry versus Versatility [0.03%]
受自然启发的聚合物纳米粒子的研究策略：专注还是求变？
Mahmoud Elsabahy,Karen L Wooley
Mahmoud Elsabahy
Polymeric nanoparticles are promising delivery platforms for various biomedical applications. One of the main challenges toward the development of therapeutic nanoparticles is the premature disassembly and release of the encapsulated drug. ...
Water-Soluble, Biocompatible Polyphosphazenes with Controllable and pH-Promoted Degradation Behavior [0.03%]
具有可控且受pH影响的降解行为的水溶性生物相容性聚磷氮烯
Sandra Wilfert,Aitziber Iturmendi,Wolfgang Schoefberger et al.
Sandra Wilfert et al.
The synthesis of a series of novel, water-soluble poly(organophosphazenes) prepared via living cationic polymerization is presented. The degradation profiles of the polyphosphazenes prepared are analyzed by GPC, 31P NMR spectroscopy, and UV...
Helena Henke,Sandra Wilfert,Aitziber Iturmendi et al.
Helena Henke et al.
Using living cationic polymerization, a series of polyphosphazenes is prepared with precisely controlled molecular weights and narrow polydispersities. As well as varying chain length through the use of a living polymerization, amine-capped...
Mark W Tibbitt,April M Kloxin,Kristi S Anseth
Mark W Tibbitt
There is a growing interest in developing dynamically responsive hydrogels whose material properties are modulated by environmental cues, including with light. These photoresponsive hydrogels afford spatiotemporal control of material proper...
Synthesis and Characterization of 5-Aminosalicylic Acid Based Poly(anhydride-esters) by Solution Polymerization [0.03%]
溶液聚合合成及表征基于5-氨基水杨酸的聚(酐酯)类高分子材料
Youngmi Kim,Kathryn E Uhrich
Youngmi Kim
A Detailed Study on Understanding Glycopolymer Library and Con A Interactions [0.03%]
对甘聚糖文库及Con A相互作用的深入研究
Yanzi Gou,Jin Geng,Sarah-Jane Richards et al.
Yanzi Gou et al.
Synthetic glycopolymers are important natural oligosaccharides mimics for many biological applications. To develop glycopolymeric drugs and therapeutic agents, factors that control the receptor-ligand interaction need to be investigated. A ...
pH-Triggered reversible morphological inversion of orthogonally-addressable poly(3-acrylamidophenylboronic acid)-block-poly(acrylamidoethylamine) micelles and their shell crosslinked nanoparticles [0.03%]
基于正交地址的聚（3-丙烯酰胺苯基硼酸）-嵌段-聚（N-乙撑亚胺甲基丙烯酰胺）胶束及其壳交联纳米粒子的pH诱导形态可逆转换
Jiong Zou,Shiyi Zhang,Ritu Shrestha et al.
Jiong Zou et al.
Functionally-responsive amphiphilic core-shell nanoscopic objects, capable of either complete or partial inversion processes, were produced by the supramolecular assembly of pH-responsive block copolymers, without or with covalent crosslink...
Synthesis and Characterization of Thiol-Ene Functionalized Siloxanes and Evaluation of their Crosslinked Network Properties [0.03%]
含硫烯功能化硅氧烷的合成与表征及其交联网络性能评估
Megan A Cole,Christopher N Bowman
Megan A Cole
Three types of linear thiol-functionalized siloxane oligomers and three types of ene-functionalized oligomers were synthesized and subsequently photopolymerized. Within each type of thiol-functionalized oligomer, the ratio of mercaptan repe...