Michael Esham,Kourtney Bryan,Jennifer Milnes et al.
Michael Esham et al.
Nebulette, a cardiac homologue of nebulin, colocalizes with alpha-actinin in the pre-myofibrils of spreading cardiomyocytes and has been hypothesized to play a critical role in the formation of the thin-filament-Z-line complex early during ...
The effect of combined simulated microgravity and microgrooved surface topography on fibroblasts [0.03%]
模拟微重力和表面拓扑结构对纤维母细胞的影响
W A Loesberg,X F Walboomers,E M Bronkhorst et al.
W A Loesberg et al.
This study evaluated in vitro the differences in morphological behaviour between fibroblast cultured on smooth and microgrooved substrata (groove depth: 0.5 microm, width: 1, 2, 5, and 10 microm), which were subjected to simulated micrograv...
Changes in cholesterol levels in the plasma membrane modulate cell signaling and regulate cell adhesion and migration on fibronectin [0.03%]
血浆膜中胆固醇水平的变化可调节细胞信号传导，并调控其在纤连蛋白上的粘附和迁移
O G Ramprasad,G Srinivas,K Sridhar Rao et al.
O G Ramprasad et al.
The number and distribution of lipid molecules, including cholesterol in particular, in the plasma membrane, may play a key role in regulating several physiological processes in cells. We investigated the role of membrane cholesterol in reg...
Cell division of Giardia intestinalis: assembly and disassembly of the adhesive disc, and the cytokinesis [0.03%]
隐孢子虫细胞分裂：粘附盘的装配和去组装及有丝分裂后期与末期阶段
Pavla Tůmová,Jaroslav Kulda,Eva Nohýnková
Pavla Tůmová
Trophozoites of Giardia are equipped with a special organelle of attachment, essential for parasite survival and pathogenicity, the ventral disc. Although its basic structure is well established, its reorganization and assembly during cell ...
Michelle E Wall,Carol Otey,Jie Qi et al.
Michelle E Wall et al.
Varieties of cell-matrix or cell-cell adhesions are associated with the actin cytoskeleton. However, for gap junctions, which are both channels and adhesions, there has been little evidence for such an association. The purpose of this study...
Comparative Study
Cell motility and the cytoskeleton. 2007 Feb;64(2):121-30. DOI:10.1002/cm.20170 2007
Reconstitution in vitro of MSP-based filopodium extension in nematode sperm [0.03%]
基于线虫精子的MSP基filopodia体外重建
Long Miao,Kexi Yi,Joy M Mackey et al.
Long Miao et al.
The major sperm protein (MSP) motility system in nematode sperm is best known for propelling the movement of mature sperm, where it has taken over the role usually played by actin in amoeboid cell motility. However, MSP filaments also drive...
Insight into the mechanism of fast movement of myosin from Chara corallina [0.03%]
一种水生被囊植物藻状念珠藻(myosin)快速运动机制的初步研究
Hiroki Sumiyoshi,Masami Ooguchi,Atsushi Ooi et al.
Hiroki Sumiyoshi et al.
Chara myosin, two-headed plant myosin belonging to class XI, slides F-actin at maximally 60 microm s(-1). To elucidate the mechanism of this fast sliding, we extensively investigated its mechanochemical properties. The maximum actin activat...
Ramesh M Ray,Rajiv J Vaidya,Leonard R Johnson
Ramesh M Ray
Polyamine depletion with the ornithine decarboxylase inhibitor alpha-difluoromethyl ornithine (DFMO), prevents Rac1 activation causing the formation of a thick actin cortex at the cell periphery and inhibits migration of intestinal epitheli...
Talin2 is induced during striated muscle differentiation and is targeted to stable adhesion complexes in mature muscle [0.03%]
塔利ん2在横纹肌分化过程中表达并在成熟肌肉中向稳定的黏附复合物靶向定位
Melissa A Senetar,Carole L Moncman,Richard O McCann
Melissa A Senetar
The cytoskeletal protein talin serves as an essential link between integrins and the actin cytoskeleton in several similar, but functionally distinct, adhesion complexes, including focal adhesions, costameres, and intercalated disks. Verteb...
Tumor-derived factors impaired motility and immune functions of dendritic cells through derangement of biophysical characteristics and reorganization of cytoskeleton [0.03%]
肿瘤衍生因子通过生物物理特性的紊乱和细胞骨架的重新组织而损害树突状细胞的运动性和免疫功能
Zhu Zeng,Xiaofeng Xu,Yingyu Zhang et al.
Zhu Zeng et al.
The generation and progress of tumors are accompanied with a marked suppression of human immune system. To explore the mechanisms by which tumors escape from immune recognition, we studied the influences of tumor microenvironment on differe...