Localization of EB1, IFT polypeptides, and kinesin-2 in Chlamydomonas flagellar axonemes via immunogold scanning electron microscopy [0.03%]
通过免疫金扫描电镜测定EB1、IFT多肽及kinesin-2在绿藻鞭毛轴丝中的定位
Roger D Sloboda,Louisa Howard
Roger D Sloboda
Intraflagellar transport (IFT) refers to the bi-directional movement of particles and associated cargo along the axonemes of eukaryotic flagella and cilia. To provide a new perspective on the morphology of IFT particles, their association w...
Analysis of the weak interactions of ADP-Unc104 and ADP-kinesin with microtubules and their inhibition by MAP2c [0.03%]
ADP-Unc104和ADP-动力蛋白与微管弱相互作用及其被MAP2c抑制的分析研究
Jawdat Al-Bassam,Benoit Roger,Shelley Halpain et al.
Jawdat Al-Bassam et al.
Microtubule based motors like conventional kinesin (Kinesin-1) and Unc104 (Kinesin-3), and classical microtubule associated proteins (MAPs), including MAP2, are intimately involved in neurite formation and organelle transport. The processiv...
Comparative Study
Cell motility and the cytoskeleton. 2007 May;64(5):377-89. DOI:10.1002/cm.20190 2007
EhGEF3, a novel Dbl family member, regulates EhRacA activation during chemotaxis and capping in Entamoeba histolytica [0.03%]
新型Dbl家族成员EhGEF3通过调节溶组织内阿米巴趋化性和顶端效应过程中的EhRacA活化发挥作用
Luis E Arias-Romero,Claudia H Gonzalez de la Rosa,Ma de Jesús Almaráz-Barrera et al.
Luis E Arias-Romero et al.
Rho GTPases are critical elements involved in the regulation of signal transduction cascades from extracellular stimuli to cytoskeleton. The Rho guanine nucleotide exchange factors (RhoGEFs) have been implicated in direct activation of thes...
Accelerated mortality from hydrocephalus and pneumonia in mice with a combined deficiency of SPAG6 and SPAG16L reveals a functional interrelationship between the two central apparatus proteins [0.03%]
SPAG6和SPAG16L联合缺乏小鼠的脑积水和肺炎加速致死揭示了这两种中心装置蛋白之间的功能关系
Zhibing Zhang,Waixing Tang,Rong Zhou et al.
Zhibing Zhang et al.
SPAG6 and SPAG16L are proteins localized to the "9+2" axoneme central apparatus. Both are essential for sperm motility and male fertility. These two proteins are also expressed in other tissues containing ciliated cells, such as brain and l...
Allicin inhibits cell polarization, migration and division via its direct effect on microtubules [0.03%]
蒜素通过其对微管的直接作用抑制细胞极化、迁移和分裂
Masha Prager-Khoutorsky,Igor Goncharov,Aharon Rabinkov et al.
Masha Prager-Khoutorsky et al.
Allicin (diallyl thiosulfinate) is a major biologically active component of garlic that is known to inhibit cell proliferation and induce apoptosis. The effects of allicin are attributed to its ability to react with thiol groups. However, t...
Comparative Study
Cell motility and the cytoskeleton. 2007 May;64(5):321-37. DOI:10.1002/cm.20185 2007
Maspin controls mammary tumor cell migration through inhibiting Rac1 and Cdc42, but not the RhoA GTPase [0.03%]
Maspin通过抑制Rac1和Cdc42但不是RhoA GTP酶来控制乳腺肿瘤细胞的迁移
Heidi Y Shi,Lewis Joe Stafford,Zhisheng Liu et al.
Heidi Y Shi et al.
Rac1 and Cdc42 are members of the Rho family of small GTPases that play essential roles in diverse cellular functions, including cell migration. The activities of these Rho family proteins are controlled by growth factor receptor activation...
Masashi Kinukawa,Victor D Vacquier
Masashi Kinukawa
Sea urchin embryos swim by ciliary movement. Hypertonic shock causes deciliation and loss of motility. Within 2-4 h, cilia regenerate and the embryos swim again. Regeneration of cilia occurs multiple times. The adenylate kinase (AK) activit...
The polypeptide composition of moving and stationary neurofilaments in cultured sympathetic neurons [0.03%]
培养的交感神经元中运动和静止神经丝多肽组成的差异
Yanping Yan,Kitty Jensen,Anthony Brown
Yanping Yan
Studies on the axonal transport of neurofilament proteins in cultured neurons have shown they move at fast rates, but their overall rate of movement is slow because they spend most of their time not moving. Using correlative light and elect...
Identification and characterization of a population of motile neurons in long-term cortical culture [0.03%]
长期皮层培养中运动神经元的识别和表征
Matilda A Haas,Jyoti A Chuckowree,Roger S Chung et al.
Matilda A Haas et al.
The specific phenotypes and progression to maturity of primary cortical neurons in long-term culture correlate well with neurons in vivo. Utilizing a model of neuronal injury in long-term cultures at 21 days in vitro (DIV), we have identifi...
Differential organelle movement on the actin cytoskeleton in lily pollen tubes [0.03%]
石竹花粉管中器官ell在肌动蛋白细胞骨架上的不同运动方式
Alenka Lovy-Wheeler,Luis Cárdenas,Joseph G Kunkel et al.
Alenka Lovy-Wheeler et al.
We have examined the arrangement and movement of three major compartments, the endoplasmic reticulum (ER), mitochondria, and the vacuole during oscillatory, polarized growth in lily pollen tubes. These movements are dependent on the actin c...