Inhibition by ATP and activation by ADP in the regulation of flagellar movement in sea urchin sperm [0.03%]
ATP抑制和ADP激活在海胆精子鞭毛运动调节中的作用
Azumi Yoshimura,Izumi Nakano,Chikako Shingyoji
Azumi Yoshimura
ATP and ADP are known to play inhibitory and activating roles, respectively, in the regulation of dynein motile activity of flagella. To elucidate how these nucleotide functions are related to the regulation of normal flagellar beating, we ...
Sumio Ishijima
Sumio Ishijima
It is now well understood that ATP-driven active sliding between the doublet microtubules in the sperm axoneme generates flagellar movement. However, much remains to be learned about how this movement is controlled. Detailed analyses of the...
Axonemal localization of Chlamydomonas PACRG, a homologue of the human Parkin-coregulated gene product [0.03%]
绿藻PACRG的轴丝定位及其与人类Parkin调节基因产物的同源性研究
Kazuho Ikeda,Takashi Ikeda,Keiko Morikawa et al.
Kazuho Ikeda et al.
A homologue of mammalian PACRG was identified in Sarkosyl-extracted Chlamydomonas axonemes as a protein that may interact with Rib72 (a component of the protofilament ribbon within the outer doublet microtubules). PACRG is a protein whose e...
Dissociated flexor digitorum brevis myofiber culture system--a more mature muscle culture system [0.03%]
分离的足底内侧小肌(myobranch)细胞系——一种更成熟的肌肉细胞培养系统
Gianina Ravenscroft,Kristen J Nowak,Connie Jackaman et al.
Gianina Ravenscroft et al.
Considerable knowledge regarding skeletal muscle physiology and disease has been gleaned from cultured myoblastic cell lines or isolated primary myoblasts. Such muscle cultures can be induced to differentiate into multinucleated myotubes th...
Membrane associated nonmuscle myosin II functions as a motor for actin-based vesicle transport in clam oocyte extracts [0.03%]
非肌肉肌球蛋白II作为缢蛏卵母细胞提取物中基于肌动蛋白的囊泡运输马达的功能
Ana S DePina,Torsten Wöllert,George M Langford
Ana S DePina
Nonmuscle myosin II (Myo2) has been shown to associate with membranes of the trans-Golgi network and to be involved in Golgi to ER retrograde protein transport. Here, we provide evidence that Myo2 not only associates with membranes but func...
The roles of noncatalytic ATP binding and ADP binding in the regulation of dynein motile activity in flagella [0.03%]
驱动蛋白动力活性调节的非催化ATP和ADP结合的作用机制研究——以鞭毛为例
Yuichi Inoue,Chikako Shingyoji
Yuichi Inoue
The regulation of dynein activity to produce microtubule sliding in flagella has not been well understood. To gain more insight into the roles of ATP and ADP in the regulation, we examined the effects of fluorescent ATP analogues and fluore...
Assessment of myosin II, Va, VI and VIIa loss of function on endocytosis and endocytic vesicle motility in bone marrow-derived dendritic cells [0.03%]
肌球蛋白II、VA、VI和VIIa的功能缺失对骨髓来源的树突状细胞内吞作用及内吞囊泡运动的影响评估
Jeffrey P Holt,Kim Bottomly,Mark S Mooseker
Jeffrey P Holt
An essential feature of dendritic cell immune surveillance is endocytic sampling of the environment for non-self antigens primarily via macropinocytosis and phagocytosis. The role of several members of the myosin family of actin based molec...
Simultaneous orientation and cellular force measurements in adult cardiac myocytes using three-dimensional polymeric microstructures [0.03%]
基于三维聚合物微结构在成年心脏肌肉细胞中同时进行方向和细胞力测量
Yi Zhao,Chee Chew Lim,Douglas Brian Sawyer et al.
Yi Zhao et al.
A number of techniques have been developed to monitor contractile function in isolated cardiac myocytes. While invaluable observations have been gained from these methodologies in understanding the contractile processes of the heart, they a...
Lateral wall protein content mediates alterations in cochlear outer hair cell mechanics before and after hearing onset [0.03%]
耳蜗外毛细胞听觉发生前后水平细胞层蛋白含量介导的机械特性变化
Heather Jensen-Smith,Richard Hallworth
Heather Jensen-Smith
Specialized outer hair cells (OHCs) housed within the mammalian cochlea exhibit active, nonlinear, mechanical responses to auditory stimulation termed electromotility. The extraordinary frequency resolution capacity of the cochlea requires ...
Ultrastructural analysis of the aberrant axoneme morphogenesis in thrips (Thysanoptera, Insecta) [0.03%]
缨尾目昆虫缨翅的异常轴突原纤维形态发生 ultrastructure分析
Eugenio Paccagnini,Caterina Mencarelli,David Mercati et al.
Eugenio Paccagnini et al.
Thrips spermiogenesis is characterized by unusual features in the differentiating spermatid cells. Three centrioles from which three individual short flagella are initially assembled, make the early spermatid a tri-flagellated cell. Success...