Locomotion of fish epidermal keratocytes on spatially selective adhesion patterns [0.03%]
基于空间选择性附着模式的鱼表皮角化细胞运动行为研究
Gabor Csucs,Katharina Quirin,Gaudenz Danuser
Gabor Csucs
Cell migration results from forces generated by assembly, contraction, and adhesion of the cytoskeleton. To address how these forces integrate in space and time, novel assays are required that allow spatial separation of the different force...
G protein betagamma subunits interact with alphabeta- and gamma-tubulin and play a role in microtubule assembly in PC12 cells [0.03%]
G蛋白的βγ亚单位与αβ-和γ-微管蛋白相互作用并在PC12细胞中参与微管装配
Valentina Montoya,Christina Gutierrez,Omar Najera et al.
Valentina Montoya et al.
The betagamma subunit of G proteins (Gbetagamma) is known to transfer signals from cell surface receptors to intracellular effector molecules. Recent results suggest that Gbetagamma also interacts with microtubules and is involved in the re...
Novel structural and functional findings of the ehFLN protein from Entamoeba histolytica [0.03%]
Entamoeba.histolytica新型结构和功能的发现
Juan Daniel Díaz-Valencia,Ma de Jesús Almaraz-Barrera,David Jay et al.
Juan Daniel Díaz-Valencia et al.
The ehFLN protein (previously known as EhABP-120) is the first filamin to be identified in the parasitic protozoan Entamoeba histolytica. Filamins are a family of cross-linking actin-binding proteins that organize filamentous actin in netwo...
Ectopic expression and dynamics of TPM1alpha and TPM1kappa in myofibrils of avian myotubes [0.03%]
TPM1α和TPM1κ在鸟类肌管肌丝中的异位表达及动态变化
Jushuo Wang,Jean M Sanger,Songman Kang et al.
Jushuo Wang et al.
From the four known vertebrate tropomyosin genes (designated TPM1, TPM2, TPM3, and TPM4) over 20 isoforms can be generated. The predominant TPM1 isoform, TPM1alpha, is specifically expressed in both skeletal and cardiac muscles. A newly dis...
Myo1 localizes to phagosomes, some of which traffic to the nucleus in a Myo1-dependent manner in Tetrahymena thermophila [0.03%]
Myo1定位于吞噬体，并且在热酸滴 Tetrahymena thermophila 中，一些吞噬体以 Myo1 依赖的方式运输到细胞核中
Roland E Hosein,R H Gavin
Roland E Hosein
Myo1 is one of 13 myosins in Tetrahymena thermophila. Initially, twelve of the myosins in Tetrahymena were assigned to Class XX in the myosin superfamily but recently re-assigned to a subclass within Class XIV. In a previous study, we repor...
Myosin II and Rho kinase activity are required for melanosome aggregation in fish retinal pigment epithelial cells [0.03%]
鱼视网膜色素上皮细胞中的黑素体聚集需要肌球蛋白II和Rho激酶活性
I B Barsoum,C King-Smith
I B Barsoum
In the retinal pigment epithelium (RPE) of fish, melanosomes (pigment granules) migrate long distances through the cell body into apical projections in the light, and aggregate back into the cell body in the dark. RPE cells can be isolated ...
Mammalian cilia function is independent of the polymeric state of tubulin glycylation [0.03%]
哺乳动物纤毛功能与tubulin糖基聚合状态无关
Starlette J Y Dossou,Marie-Hélène Bré,Richard Hallworth
Starlette J Y Dossou
Polyglycylation is a polymeric post-translational modification of tubulin that is ubiquitous and widely present in cilia and flagella. It consists of the addition of highly variable numbers of glycyl residues as side chains onto the gamma c...
Electric field-induced polarization of charged cell surface proteins does not determine the direction of galvanotaxis [0.03%]
电场诱发的细胞表面蛋白定向分布与电压导航无关
Erik I Finkelstein,Pen-hsiu Grace Chao,Clark T Hung et al.
Erik I Finkelstein et al.
Galvanotaxis, that is, migration induced by DC electric fields, is thought to play a significant role in development and wound healing, however, the mechanisms by which extrinsic electric fields orchestrate intrinsic motility responses are ...
Versatile fluorescent probes for actin filaments based on the actin-binding domain of utrophin [0.03%]
基于神经营养素受体蛋白的肌动蛋白丝多功能荧光探针
Brian M Burkel,George von Dassow,William M Bement
Brian M Burkel
Actin filaments (F-actin) are protein polymers that undergo rapid assembly and disassembly and control an enormous variety of cellular processes ranging from force production to regulation of signal transduction. Consequently, imaging of F-...
Jonathan D Steels,Mathew P Estey,Carol D Froese et al.
Jonathan D Steels et al.
Since their essential role in cytokinesis was first shown in yeast, the septins have been described to function in diverse cellular contexts. The members of this unique class of GTPases are capable of binding and hydrolyzing GTP, associatin...