Jianxin Chen,Hongxia Li,Nirmala SundarRaj et al.
Jianxin Chen et al.
Using an established corneal stromal cell differentiation model, we manipulated alpha-smooth muscle actin (alpha-SMA) protein expression levels in fibroblasts by treating them with TGF-beta1, bFGF, TGF-beta type I receptor inhibitor (SB-431...
Actin deficiency induces cofilin phosphorylation: proteome analysis of HeLa cells after beta-actin gene silencing [0.03%]
肌动蛋白缺乏诱导科芬林磷酸化：沉默β-肌动蛋白基因后HeLa细胞的蛋白质组分析
Ning Liu,Katrina Academia,Teresa Rubio et al.
Ning Liu et al.
Actin-binding proteins regulate the dynamic structure and function of actin filaments in the cell. Much is known about how manipulation of the actin-binding proteins affects the structure and function of actin filaments; however, little is ...
Myosin16b: The COOH-tail region directs localization to the nucleus and overexpression delays S-phase progression [0.03%]
肌球蛋白16b：COOH尾区决定其向细胞核定位及过量表达延缓S期进程
Richard S Cameron,Changdan Liu,April S Mixon et al.
Richard S Cameron et al.
Rat Myo16a and Myo16b comprise the founding members of class XVI myosin and are characterized by an N-terminal ankyrin repeat domain thought to mediate an association with protein phosphatase 1 catalytic subunits 1alpha and 1gamma. Myo16b i...
The M3/M4 cytoplasmic loop of the alpha1 subunit restricts GABAARs lateral mobility: a study using fluorescence recovery after photobleaching [0.03%]
应用荧光淬灭后恢复技术研究GABA受体侧向移动性受限于α1亚单位的M3/M4胞质环区域内
Macarena Perán,Helen Hooper,Houria Boulaiz et al.
Macarena Perán et al.
A crucial problem in neurobiology is how neurons are able to maintain neurotransmitter receptors at specific membrane domains. The large structural heterogeneity of gamma aminobutyric acid receptors (GABAARs) led to the hypothesis that ther...
Shroom4 (Kiaa1202) is an actin-associated protein implicated in cytoskeletal organization [0.03%]
Fung4（Kiaa1202）是一种与肌动蛋白相关并参与细胞骨架组织的蛋白质
Michael Yoder,Jeffrey D Hildebrand
Michael Yoder
All animal cells utilize a specialized set of cytoskeletal proteins to determine their overall shape and the organization of their intracellular compartments and organelles. During embryonic development, the dynamic nature of the actin cyto...
Living markers for actin block myosin-dependent motility of plant organelles and auxin [0.03%]
肌动蛋白阻挡肌球蛋白依赖性植物细胞器和生长素运动的活体示踪標记
Carola L Holweg
Carola L Holweg
Expression-based techniques using recombinant actin-binding proteins (ABPs) have been developed as advantageous means of visualising actin filaments. As actin function is linked to the movement of cellular cargoes, and overexpression of ABP...
David Woolley,Catarina Gadelha,Keith Gull
David Woolley
Motility in trypanosomes is achieved through the undulating behaviour of a single "9 + 2" flagellum; normally the flagellar waves begin at the flagellar tip and propagate towards the base. For flagella in general, however, propagation is fr...
The control of microtubule stability in vitro and in transfected cells by MAP1B and SCG10 [0.03%]
MAP1B和SCG10对体外及转染细胞中微管稳定性的调节作用
Percy Bondallaz,Anne Barbier,Sophia Soehrman et al.
Percy Bondallaz et al.
In neurons, the regulation of microtubules plays an important role for neurite outgrowth, axonal elongation, and growth cone steering. SCG10 family proteins are the only known neuronal proteins that have a strong destabilizing effect, are h...
Migration of bone marrow stromal cells in 3D: 4 color methodology reveals spatially and temporally coordinated events [0.03%]
三维骨髓基质细胞迁移：四色技术揭示时空协调事件
Marc M Thibault,Michael D Buschmann
Marc M Thibault
The cytoskeleton plays a central role in many cell processes including directed cell migration. Since most previous work has investigated cell migration in two dimensions (2D), new methods are required to study movement in three dimensions ...
Hassina Darenfed,Bama Dayanandan,Tong Zhang et al.
Hassina Darenfed et al.
Many key cellular functions, such as cell motility and cellular differentiation are mediated by Rho-associated protein kinases (ROCKs). Numerous studies have been conducted to examine the ROCK signal transduction pathways involved in these ...