Molecular imaging with surface-enhanced Raman spectroscopy nanoparticle reporters [0.03%]
基于表面增强拉曼光谱的纳米颗粒探针的分子影像学研究
Jesse V Jokerst,Christoph Pohling,Sanjiv S Gambhir
Jesse V Jokerst
Molecular imaging scans cellular and molecular targets in living subjects through the introduction of imaging agents that bind to these targets and report their presence through a measurable signal. The picomolar sensitivity, signal stabili...
Wound Healing Versus Regeneration: Role of the Tissue Environment in Regenerative Medicine [0.03%]
伤口愈合与再生：组织微环境在再生医学中的作用
Anthony Atala,Darrell J Irvine,Marsha Moses et al.
Anthony Atala et al.
One of the major challenges in the field of regenerative medicine is how to optimize tissue regeneration in the body by therapeutically manipulating its natural ability to form scar at the time of injury or disease. It is often the balance ...
Markus J Buehler
Markus J Buehler
Biological materials are effectively synthesized, controlled, and used for a variety of purposes-in spite of limitations in energy, quality, and quantity of their building blocks. Whereas the chemical composition of materials in the living ...
Development of Electron Energy Loss Spectroscopy in the Biological Sciences [0.03%]
电子能量损失谱在生物科学中的发展
M A Aronova,R D Leapman
M A Aronova
The high sensitivity of electron energy loss spectroscopy (EELS) for detecting light elements at the nanoscale makes it a valuable technique for application to biological systems. In particular, EELS provides quantitative information about ...
Charles M Lieber
Charles M Lieber
Advances in nanoscience and nanotechnology critically depend on the development of nanostructures whose properties are controlled during synthesis. We focus on this critical concept using semiconductor nanowires, which provide the capabilit...
Lars D Renner,Douglas B Weibel
Lars D Renner
This article reviews the physical and chemical constraints of environments on biofilm formation. We provide a perspective on how materials science and engineering can address fundamental questions and unmet technological challenges in this ...
The contribution of cell-cell signaling and motility to bacterial biofilm formation [0.03%]
细胞信号转导和运动性在细菌生物膜形成中的作用
Joshua D Shrout,Tim Tolker-Nielsen,Michael Givskov et al.
Joshua D Shrout et al.
Many bacteria grow attached to a surface as biofilms. Several factors dictate biofilm formation, including responses by the colonizing bacteria to their environment. Here we review how bacteria use cell-cell signaling (also called quorum se...
Shape and Biomechanical Characteristics of Human Red Blood Cells in Health and Disease [0.03%]
健康与疾病状态下的人体红细胞形态及生物力学特征分析研究报告
Monica Diez-Silva,Ming Dao,Jongyoon Han et al.
Monica Diez-Silva et al.
The biconcave shape and corresponding deformability of the human red blood cell (RBC) is an essential feature of its biological function. This feature of RBCs can be critically affected by genetic or acquired pathological conditions. In thi...
F Sachs,W E Brownell,A G Petrov
F Sachs
Cells are ion conductive gels surrounded by a ~5-nm-thick insulating membrane, and molecular ionic pumps in the membrane establish an internal potential of approximately -90 mV. This electrical energy store is used for high-speed communicat...
Ronak V Rughani,Joel P Schneider
Ronak V Rughani
Self-assembled materials composed of beta-sheet forming peptides hold promise as therapeutics and novel biomaterials. This article focuses on the design and engineering of amphiphilic peptide sequences, especially beta-hairpins. Peptides ca...