Thapsigargin inhibits the effects of noradrenaline and high [Ca2+]o on kinetics but not on amplitude of contraction in the single myocytes of guinea-pig heart [0.03%]
甲状腺素抑制去甲肾上腺素和高钙对心脏单细胞收缩幅度以外的各项指标的作用
R Janiak,B Lewartowski
R Janiak
We investigated the effect of selective blocker of Ca(2+)-ATPase of sarcoplasmic reticulum (SR), thapsigargin (TG), on the responses of single myocytes of guinea-pig heart to high [Ca2+]o and noradrenaline (NA). The cells were loaded with a...
The effect of nitric oxide donors on the release of plasminogen activator inhibitor (PAI) from rabbit platelets in vitro [0.03%]
一氧化氮供体对兔血小板释放组织型纤溶酶原激活物抑制剂的影响
R Korbut,E Marcinkiewicz,K Cieślik et al.
R Korbut et al.
Here we describe effects of four nitric oxide (NO) donors, 4-arylsubstituted oxatriazol derivatives and 3-morpholino-sydnonimine (SIN-1) at concentrations of 30-1000 microM on the release of plasminogen activator inhibitor (PAI) from rabbit...
Prevention and treatment of ulcers induced by nonsteroidal anti-inflammatory drugs: an update [0.03%]
非甾体抗炎药引起的溃疡的防治进展
E Z Dajani,N M Agrawal
E Z Dajani
Nonsteroidal anti-inflammatory drugs (NSAIDs) are most frequently used for the treatment of rheumatic disease due to their anti-inflammatory and analgesic properties. All NSAIDs have the potential to cause damage to the gastrointestinal (GI...
Modulation of human sympathetic periodicity by mild, brief hypoxia and hypercapnia [0.03%]
轻度间歇性低氧及高碳酸血症对人交感神经周期性的调节作用
A Trzebski,M L Smith,L A Beightol et al.
A Trzebski et al.
We determined the influence of brief mild normocapnic hyperoxia, hypoxia, and hyperoxic hypercapnia on human muscle sympathetic nerve activity and R-R intervals, as quantified by both time- and frequency-domain analyses. We obtained measure...
The detection of specific acute phase serum protein complexes and immune complexes by congo red binding [0.03%]
刚果红结合特异急性期血清蛋白质复合物及免疫复合物的检测
J Rybarska,L Konieczny,B Piekarska et al.
J Rybarska et al.
The study concerns the problem of selective binding of Congo Red dye to serum proteins. The dye-binding structural motifs were assumed to appear in proteins as the result of local disruptions of tertiary interaction associated with biologic...
The effect of caerulein-induced acute pancreatitis on the levels of serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) in various rat tissues [0.03%]
卡立林诱导的大鼠急性胰腺炎对其多种组织中血清素(5-ht)和5-羟基吲哚乙酸(5-hiaa)水平影响的研究
K Celiński,Z Kleinrok,J Pokora et al.
K Celiński et al.
The effects of caerulein-induced acute pancreatitis (AP) on the levels of 5-HT and 5-HIAA in pancreas, liver, brain, kidney and different parts of the digestive tract in rats have been studied. The acute pancreatitis was induced by the cont...
G Ciurzyńska,J Dzierzkowska,S Maśliński
G Ciurzyńska
The role of endogenous serotinin in the formation of gastric damage was studied in rats. Stress ulcers were induced by ultrasounds, immobilization and immobilization plus cold. The damage of gastric mucosa was estimated (arbitrary scale) an...
Relations between Fc epsilon RI crosslinking-induced mast cell activation and adhesion to fibronectin [0.03%]
FcεRI交联诱导的肥大细胞活化与黏附于纤连蛋白之间的关系
J Wyczółkowska,J Dastych,A Slusarczyk et al.
J Wyczółkowska et al.
Demonstration of murine mast cell adhesion to fibronectin (FN) following PMA-mediated cell activation raised the question whether crosslinking of high affinity IgE receptors on mouse mast cells might induce changes in adhesiveness of these ...
Molecular mechanism of histamine release: the role of intermediate filaments and membrane skeletons [0.03%]
组胺释放的分子机制：中间丝和膜骨架的作用
K Tasaka
K Tasaka
It has been recognized that cytoskeletons play some important roles in the histamine release from mast cells. We previously reported the role of microfilaments and microtubules in the histamine release from mast cells, and in the present st...
Pharmacology of histamine liberation. Cationic amphiphilic drugs and mast cells [0.03%]
组胺释放的药理学。阳离子两亲性药物和肥大细胞
R Nosál
R Nosál
The effect of betaadrenoceptor blocking drugs atenolol and propranolol was studied in both nonstimulated and stimulated isolated rat mast cells. Atenolol did not liberate histamine from non-stimulated mast cells, decreased spontaneous secre...