Impact of Compensation Coefficients on Active Sequential Change-Point Detection [0.03%]
补偿系数对主动序贯变点检测的影响分析
Qunzhi Xu,Yajun Mei,Jianjun Shi
Qunzhi Xu
Under a general setting of active sequential change-point detection problems, there are p local streams in a system but we are only able to take observations from q out of these p local streams at each time instant due to the sampling contr...
Data-Adaptive Symmetric CUSUM for Sequential Change Detection [0.03%]
数据自适应对称CUmulative SUM法及其在序列变化检测中的应用
Nauman Ahad,Mark A Davenport,Yao Xie
Nauman Ahad
Detecting change points sequentially in a streaming setting, especially when both the mean and the variance of the signal can change, is often a challenging task. A key difficulty in this context often involves setting an appropriate detect...
Asymptotic Optimality Theory for Active Quickest Detection with Unknown PostChange Parameters [0.03%]
未知变化后参数的主动快速检测的渐近最优理论
Qunzhi Xu,Yajun Mei
Qunzhi Xu
The active quickest detection problem with unknown post-change parameters is studied under the sampling control constraint, where there are p local streams in a system but one is only able to take observations from one and only one of these...
Sequential Tests of Multiple Hypotheses Controlling False Discovery and Nondiscovery Rates [0.03%]
控制错误发现率和未发现率的多重假设检验的序贯方法
Jay Bartroff,Jinlin Song
Jay Bartroff
We propose a general and flexible procedure for testing multiple hypotheses about sequential (or streaming) data that simultaneously controls both the false discovery rate (FDR) and false nondiscovery rate (FNR) under minimal assumptions ab...
Exact conditional maximized sequential probability ratio test adjusted for covariates [0.03%]
针对混杂因素调整的精确条件最大化序贯概率比检验
Ivair R Silva,Lingling Li,Martin Kulldorff
Ivair R Silva
Sequential analysis is now commonly used for post-market drug and vaccine safety surveillance, and a Poisson stochastic process is typically used for rare adverse events. The conditional maximized sequential probability ratio test, CMaxSPRT...
Flexibly Monitoring Group Sequential Survival Trials When Testing is Based Upon a Weighted Log-Rank Statistic [0.03%]
基于加权log-rank统计量的分组序贯生存试验的灵活监控方法研究
Sean S Brummel,Daniel L Gillen
Sean S Brummel
We consider the repeated group sequential testing of a survival endpoint with a time-varying treatment effect using a weighted logrank statistic. The emphasis of this paper is on the monitoring of this statistic where information growth is ...
Group sequential crossover trial designs with strong control of the familywise error rate [0.03%]
一类能够严格控制家族误差率的序贯交叉试验设计方法
Michael J Grayling,James M S Wason,Adrian P Mander
Michael J Grayling
Crossover designs are an extremely useful tool to investigators, and group sequential methods have proven highly proficient at improving the efficiency of parallel group trials. Yet, group sequential methods and crossover designs have rarel...
Generalized Sequential Probability Ratio Test for Separate Families of Hypotheses [0.03%]
假设类的广义序贯概率比检验方法研究
Xiaoou Li,Jingchen Liu,Zhiliang Ying
Xiaoou Li
In this paper, we consider the problem of testing two separate families of hypotheses via a generalization of the sequential probability ratio test. In particular, the generalized likelihood ratio statistic is considered and the stopping ru...
Efficient Adaptive Randomization and Stopping Rules in Multi-arm Clinical Trials for Testing a New Treatment [0.03%]
多重臂临床试验中测试新疗法的有效自适应随机化和停止规则
Tze Leung Lai,Olivia Yueh-Wen Liao
Tze Leung Lai
Motivated by applications to confirmatory clinical trials for testing a new treatment against a placebo or active control when the new treatment has k possible treatment strategies (arms)-for example, k possible doses for a new drug-we deve...
On an Inequality That Implies the Lower Bound Formula for the Probability of Correct Selection in the Levin-Robbins-Leu Family of Sequential Binomial Subset Selection Procedures [0.03%]
蕴含列文-罗宾斯-娄序贯二项式择优问题正确选择概率渐近下界的不等式
Bruce Levin,Cheng-Shiun Leu
Bruce Levin
We study a key inequality that implies the lower bound formula for the probability of correct selection and other selection-related events of interest in the Levin-Robbins-Leu family of sequential binomial subset selection procedures. We pr...