Maria Pimenova,Matthew W Rosenbaum
Maria Pimenova
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related deaths, accounting for over 90 % of pancreatic cancer cases. Accurate diagnosis is crucial, but often challenging. It typically relies on minimally invasive proced...
Douglas Jian-Xian Wu,Emily Chan
Douglas Jian-Xian Wu
Conventional urothelial carcinoma in its invasive form has a relatively nonspecific morphologic description, frequently described as nests of epithelial cells containing hyperchromatic and pleomorphic nuclei, with readily identified mitotic...
Wilson Duplessis,Jason K Wasserman
Wilson Duplessis
Avash Das,Paolo M Chetta,M Lisa Zhang
Avash Das
Gastrointestinal adenocarcinomas, including colorectal cancer (CRC) and gastroesophageal junction (GEJ) carcinoma, represent a significant global health burden. Recent advances in large-scale multi-omics profiling, particularly through The ...
Annikka Weissferdt
Annikka Weissferdt
Tumors of mesenchymal origin only rarely arise in the bronchopulmonary system and range from indolent neoplasms to highly malignant sarcomas. While many of these tumors occur more frequently outside of the thoracic cavity, there are some me...
Multiple Myeloma: A Structured and Multidisciplinary Approach to Diagnosis [0.03%]
浆细胞瘤的诊断：结构化和多学科的方法
Nourhan Ibrahim,Daniel Rivera,Janhavi Govande et al.
Nourhan Ibrahim et al.
Multiple myeloma is a hematologic malignancy characterized by the clonal proliferation of post-germinal center B cells, leading to monoclonal immunoglobulin (M protein) production. Its diagnosis remains complex due to diverse clinical prese...
Julie C Fanburg-Smith,Zachary Corey,Jessica D Smith
Julie C Fanburg-Smith
Background: Pseudoendocrine sarcoma is a recently described rare, epithelioid neuroendocrine-like soft tissue neoplasm with a distinctive phenotype. Predominantly affecting older adults in paraspinal locations, including ...
Giorgia Arcovito,Alessandro Franchi
Giorgia Arcovito
Thyroid angiosarcoma (TAS) is an aggressive vascular tumor, accounting for 20 % of thyroid mesenchymal neoplasms and affecting elderly patients with frequent extra-thyroidal local extension and distant spread. It usually arises in the conte...
John M Gross,Karen J Fritchie
John M Gross
Calcified chondroid mesenchymal neoplasm (CCMN) is a recently described benign matrix-forming soft tissue tumor with a predilection for the distal extremities and the temporomandibular joint (TMJ) of adults which frequently harbors FN1 fusi...
Sharon Koorse Germans,Bo Zhang,Olga Weinberg
Sharon Koorse Germans
Multiple myeloma (MM) is a hematologic malignancy characterized by the clonal proliferation of plasma cells within the bone marrow, leading to significant end-organ damage. Recent therapeutic advancements, including immunomodulatory drugs (...