Human West Nile virus lineage 2 neuroinvasive infection as a cause of fatal Guillain-Barré syndrome [0.03%]
人感染西尼罗病毒2型导致的吉兰-巴雷综合征致命病例
Antonio Mastroianni,Sonia Greco,Concetta Castilletti
Antonio Mastroianni
Background: West Nile virus (WNV) is now endemic in Europe and continues to spread to several countries, with strains 1 and 2 primarily responsible for outbreaks. According to the European Centre for Disease Prevention an...
Postmortem cerebellar and brainstem alterations in episodic ataxia type 1 and 2: Expanding the clinicopathological spectrum [0.03%]
遗传性阵发性共济失调1型和2型死后小脑和脑干改变：扩大临床病理学谱系
Jeroen J de Vries,Maria João da Costa Caiado,Wilfred F A den Dunnen
Jeroen J de Vries
Background: Episodic ataxias (EAs) are rare autosomal-dominant channelopathies presenting with recurrent attacks of ataxia and variable neurological features. While MRI studies suggest mild cerebellar atrophy in some pati...
From genes to neuropathology: Integrative perspectives on the spectrum of spinocerebellar ataxias [0.03%]
从基因到神经病理学：脊髓小脑共济失调谱系的综合视角
Jeroen J de Vries,Maria João da Costa Caiado,Wilfred F A den Dunnen
Jeroen J de Vries
This review describes the clinically and genetically heterogenous group of 52 Spinocerebellar ataxias (SCAs). After a brief description of the epidemiology and clinical spectrum, this review highlights the functional neuroanatomy, the need ...
Progressive multifocal leukoencephalopathy as the first presentation of an underlying lymphoproliferative disorder [0.03%]
淋巴增生性疾病的最初表现为进行性多灶性白质脑病
Jennifer Garry,Sophie Sabherwal,Seamus Looby et al.
Jennifer Garry et al.
Progressive multifocal leukoencephalopathy (PML) is a demyelinating central nervous system disease caused by John Cunningham virus (JCV) reactivation in immunosuppressed patients. Although classically associated with advanced HIV infection,...
Rapid polymer-based immunohistochemistry for intraoperative CNS tumor diagnosis: A validation study [0.03%]
基于聚合物的快速免疫组化技术在脑神经肿瘤术中诊断中的应用价值研究
Julia Schuler,Sandra Baur,Federico Fusco et al.
Julia Schuler et al.
Intraoperative diagnostics in neuro-oncology face a critical gap between the morphological limitations of hematoxylin-eosin staining or toluidine blue staining and the time-intensive nature of conventional immunohistochemistry (IHC). This d...
Christian Mawrin
Christian Mawrin
Neuronal and glial intranuclear inclusions in a patient with oculopharyngodistal myopathy associated with noncoding GGC repeat expansions in GIPC1 [0.03%]
GIPC1非编码GGC重复序列扩增的眼咽远端肌病患者的神经元和胶质细胞核内包涵体
Kaoru Yagita,Hotake Takizawa,Terunori Sano et al.
Kaoru Yagita et al.
Noncoding GGC repeat expansion of various genes leads to oculopharyngodistal myopathy (OPDM), an adult-onset progressive neuromuscular disorder characterized by ophthalmoplegia, pharyngeal dysfunction, and distal limb muscular weakness. Rec...
Bifocal cerebellar liponeurocytoma with atypical features: A case report and a literature review [0.03%]
具有不典型特征的双焦点小脑脂质神经细胞瘤一例报告及文献复习
Maysa Al-Hussaini,Sarah Al Sharie,Saif Azzam et al.
Maysa Al-Hussaini et al.
Cerebellar liponeurocytoma (cLNC) is a rare tumor. It affects adults with no sex predilection. It appears as a heterogeneously enhancing mass, most commonly unifocal. Histologically, it is a biphasic neurocytic tumor with lipomatous compone...
Evidence of blood-brain barrier disruption in pathologic stage IV chronic traumatic encephalopathy without dementia [0.03%]
无痴呆病史的病理分期4期慢性创伤性脑病患者出现血脑屏障破坏现象的证据
Jeff Henderson,Adam McGlinchey,Bríd Murphy et al.
Jeff Henderson et al.
Repetitive head injury in athletes has been increasingly linked to the development of chronic traumatic encephalopathy (CTE), a progressive neurodegenerative disorder. However, its underlying pathobiology remains poorly understood, and defi...
Glioblastoma, IDH-wildtype with melanocytic differentiation: An exceedingly rare morphology and immunophenotype [0.03%]
IDH野生型胶质母细胞瘤伴黑色素细胞分化：一种罕见的形态和免疫表型
Simone Poidomani,Serena Salzano,Gaetano Magro et al.
Simone Poidomani et al.