Ewa Sewerynek,Michał Stuss
Ewa Sewerynek
Osteoporosis is a growing problem in an ageing society. It affects women of post-menopausal age, as well as elderly subjects of both sexes, often with dysfunction of the cardiovascular system or with an increased risk of circulation disorde...
Osteonecrosis of the jaw [0.03%]
颌骨坏死
Bogna Drozdzowska
Bogna Drozdzowska
This review looks at osteonecrosis in the stomatognathic system (mainly the jaws). Osteonecrosis of the jaw (ONJ) is a rare but serious clinical condition. It affects patients treated with bisphosphonates, and also with denosumab, mainly in...
Atypical subtrochanteric fractures after long-term bisphosphonate therapy [0.03%]
长期双膦酸盐治疗后的非典型转子下骨折
Edward Czerwiński
Edward Czerwiński
There have been many reports published in recent years on atypical subtrochanteric fractures after long-term bisphosphonates therapy. In a description of a few series of cases, fractures of typical clinical course and radiological image hav...
Edward Franek
Edward Franek
Denosumab is the international name of a human, monoclonal antibody approved for the treatment of osteoporosis. This antibody is associated with RANK ligand (RANKL), inactivating it. In consequence, the formation and survival of osteoclasts...
Parathyroid hormone and its analogues--molecular mechanisms of action and efficacy in osteoporosis therapy [0.03%]
甲状旁腺激素及其类似物的分子作用机制及在骨质疏松症治疗中的有效性的研究进展
Waldemar Misiorowski
Waldemar Misiorowski
Most medical agents currently applied in osteoporosis therapy act by inhibiting bone resorption and reducing bone remodelling, i.e. they inhibit the process of bone mass loss by suppressing bone resorption processes. These drugs provide an ...
Jerzy Przedlacki
Jerzy Przedlacki
Strontium ranelate is one of the first-line agents with proven anti-fracture activity used in the therapy of post-menopausal osteoporosis. Its mechanism of action makes it, however, different from other drugs, since it simultaneously stimul...
Wanda Horst-Sikorska,Anna Wawrzyniak
Wanda Horst-Sikorska
In developed societies, the post-menopausal period covers approximately one third of a woman's life. The deficit of oestrogens observed during the post-menopausal period significantly affects the course of many metabolic processes, causing ...
Ewa Sewerynek,Michał Stuss
Ewa Sewerynek
Osteoporosis is a chronic disease of the osseous system characterised by decreased strength of bone tissue, which in turn leads to increased fracture risk. It has been demonstrated that osteoporosis affects more than 30% of women after the ...
Wojciech Pluskiewicz
Wojciech Pluskiewicz
Loss of bone mineral density and fractures in patients after stroke are among the most serious health complications. Regarding serious post-stroke impediments, significantly contributing to elevated fracture incidence are falls. An increasi...
The role of anorexia nervosa in secondary osteoporosis development with the risk for low energy fractures [0.03%]
神经性厌食症在继发性骨质疏松症发病中的作用及低能量骨折风险评估
Wanda Horst-Sikorska,Magdalena Ignaszak-Szczepaniak
Wanda Horst-Sikorska
Anorexia nervosa (AN) has in recent years become considerably more common. The disease primarily affects girls and young women, and also boys and young men. AN is a risk factor for secondary osteoporosis. AN-related metabolic disturbances l...