A high-resolution finite-difference method for simulating two-fluid, viscoelastic gel dynamics [0.03%]
一种高分辨率有限差分法模拟两流体、粘弹凝胶动力学
Grady B Wright,Robert D Guy,Jian Du et al.
Grady B Wright et al.
An important class of gels are those composed of a polymer network and fluid solvent. The mechanical and rheological properties of these two-fluid gels can change dramatically in response to temperature, stress, and chemical stimulus. Becau...
A Computational Framework for the Swelling Dynamics of Mucin-like Polyelectrolyte Gels [0.03%]
计算模拟多价离子和盐浓度对黏蛋白凝胶溶胀动力学影响的框架
Jian Du,Bindi M Nagda,Owen L Lewis et al.
Jian Du et al.
Gastric mucus is a polyelectrolyte gel that serves as the primary defense of the stomach lining against acid and digestive enzymes. Mucus is released from granules in specialized cells where it is stored at very high concentration. Experime...
Effects of Kinematic Hardening of Mucus Polymers in an Airway Closure Model [0.03%]
气道闭合模型中黏液聚合物 kinematic 硬化的影响
Bartu Fazla,Oguzhan Erken,Daulet Izbassarov et al.
Bartu Fazla et al.
The formation of a liquid plug inside a human airway, known as airway closure, is computationally studied by considering the elastoviscoplastic (EVP) properties of the pulmonary mucus covering the airway walls for a range of liquid film thi...
Bin Hu,Sarah L Kieweg
Bin Hu
The moving contact line of a thin fluid film can often corrugate into fingers, which is also known as a fingering instability. Although the fingering instability of Newtonian fluids has been studied extensively, there are few studies publis...
Vitaly O Kheyfets,Sarah L Kieweg
Vitaly O Kheyfets
The thin film lubrication approximation has been studied extensively for moving contact lines of Newtonian fluids. However, many industrial and biological applications of the thin film equation involve shear-thinning fluids, which often als...
Transient spreading and swelling behavior of a gel deploying an anti-HIV topical microbicide [0.03%]
一种短暂扩散和膨胀行为的凝胶用于递送抗艾滋病的局部微生物药物
Savas Tasoglu,David F Katz,Andrew J Szeri
Savas Tasoglu
Drug delivery of topical microbicidal molecules against HIV offers promise as a modality to prevent sexual transmission of the virus. Success of any microbicide product depends, in an interactive way, upon its drug (the microbicide active p...
The consequences of yield stress on deployment of a non-Newtonian anti-HIV microbicide gel [0.03%]
屈服应力对非牛顿抗艾滋病阴道凝胶给药方式影响的研究
Savas Tasoglu,Su Chan Park,Jennifer J Peters et al.
Savas Tasoglu et al.
A recent study in South Africa has confirmed, for the first time, that a vaginal gel formulation of the antiretroviral drug Tenofovir, when applied topically, significantly inhibits sexual HIV transmission to women [10]. However the gel for...
Extensions of the Ferry shear wave model for active linear and nonlinear microrheology [0.03%]
扩展摆渡剪切波模型以主动线性和非线性微流变学的研究
Sorin M Mitran,M Gregory Forest,Lingxing Yao et al.
Sorin M Mitran et al.
The classical oscillatory shear wave model of Ferry et al. [J. Polym. Sci. 2:593-611, (1947)] is extended for active linear and nonlinear microrheology. In the Ferry protocol, oscillation and attenuation lengths of the shear wave measured f...