[Inhibitory effect of total saponins of Panax notoginseng on rat bone marrow mesenchymal stem cell apoptosis] [0.03%]
田七总皂苷对骨髓间充质干细胞凋亡的抑制作用
Yong-Fang Ou,Xue-Kun Fu,Xing-Sha Mei et al.
Yong-Fang Ou et al.
The study was aimed to investigate the effects of total saponins of Panax notoginseng (tPNS) on cobalt chloride (CoCl2)-induced apoptosis of rat bone marrow mesenchymal stem cells (rBMSCs) and the underlying mechanism. rBMSCs were isolated ...
Target genes regulated by transcription factor E2F1 in small cell lung cancer [0.03%]
小细胞肺癌中转录因子E2F1的靶基因
Zun-Ling Li,Fei Jiao,Ying Ma et al.
Zun-Ling Li et al.
Previously, we have reported that transcription factor E2F1 expression is up-regulated in approximately 95% of small cell lung cancer tissue samples and closely associated with invasion and metastasis, but few studies have investigated spec...
[Neuroprotective effects of a novel antidiabetic drug (D-Ser2)Oxm on amyloid β protein-induced cytotoxicity] [0.03%]
[D- Ser2]Oxm新型抗糖尿病药物对淀粉样β蛋白诱导的细胞毒性的神经营养保护作用研究
Yu-Fei Han,Christian Holscher,Zhao-Jun Wang et al.
Yu-Fei Han et al.
The accumulation and neurotoxicity of amyloid β protein (Aβ) in the brain is one of major pathological hallmarks of Alzheimer's disease (AD). The effective drugs against Aβ have been still deficient up to now. According to a most recent ...
[Effective connectivity within the default mode network modulated by methylphenidate using dynamic causal modeling on resting-state functional magnetic resonance imaging] [0.03%]
[使用动态因果模型在静息态功能磁共振成像中观察到的注意缺陷多动障碍的大脑默认网络的有效连接性受盐酸哌甲酯调节]
Fang-Fang Xu,Lu Han,Hong-Jian He et al.
Fang-Fang Xu et al.
The effective connectivity of default mode network (DMN) and its change after taking methylphenidate (MPH) were investigated in this study based on resting-state functional magnetic resonance imaging. Dynamic causal modeling (DCM) was appli...
Zhou-Yi Lai,Hai-Bo Wang,Rui-Ling Lv et al.
Zhou-Yi Lai et al.
The aim of this study was to investigate the relationship between the acetylcholine concentration in the blood and gelsenicine-induced death in mice. Kunming mice were given intraperitoneal injections of normal saline, gelsenicine or differ...
[Inhibition of prostaglandins synthesis in the inflamed site results in opioid-mediated hypoalgesia in rats] [0.03%]
炎症部位抑制前列腺素合成产生阿片类介导的镇痛作用
Jian Huang,Jian Wu,Huai-Zu Yang et al.
Jian Huang et al.
This study was designed to investigate the contribution of prostaglandins to the maintenance of inflammatory pain. Inflammation was induced by intraplantar (i.pl.) injection of carrageenan in right hindpaw in rats. Indomethacin (non-selecti...
Yan-Qing Li,Qiu-Min LE,Xiang-Chen Yu et al.
Yan-Qing Li et al.
Caloric diet, such as fat and sugar intake, has rewarding effects, and has been indicated to affect the responses to addictive substances in animal experiments. However, the possible association between sucrose reward and the motivation for...
Xin Zhao,Hui-Zhu Liu,Yu-Qiu Zhang
Xin Zhao
Cancer pain is one of the most common symptoms in patients with late stage cancer. Lung, breast and prostate carcinoma are the most common causes of pain from osseous metastasis. P2X7 receptor (P2X7R) is one of the subtypes of ATP-gated pur...
Effects of environmental stress on the depression-like behaviors and the diurnal rhythm of corticosterone and melatonin in male rats [0.03%]
环境压力对雄性大鼠抑郁样行为及皮质酮和褪黑素昼夜节律的影响
Ming Yuan,Li-Jing Liu,Ling-Zhi Xu et al.
Ming Yuan et al.
Environmental stress (ES) is commonly used in producing chronic unpredictable mild stress to study pathogenesis of depression, including the regulatory role of circadian system on depression. However, the direct effect of ES on the circadia...
Si Zhang,Nan Huang,Xia Pan et al.
Si Zhang et al.
Eukaryotic translation initiation factor 4G (eIF4G) is a scaffold component of eukaryotic translation initiation factor 4F (eIF4F) complex, which takes principal part in the initiating of protein synthesis. Both two subtypes (eIF4G1 and eIF...