[Up-regulation of ErbB3-binding protein 1 inhibits the growth of esophageal carcinoma cells] [0.03%]
ErbB3结合蛋白1的上调抑制食管癌细胞生长
Hao Jiang,Dong-Ping Liu,Dong Xie et al.
Hao Jiang et al.
The objective of this study was to investigate the role of ErbB3-binding protein 1 (Ebp1) in the growth of esophageal squamous cell carcinoma (ESCC) cells and the underlying mechanism. Eca109 and KYSE150 cells were transfected with lentivir...
[Advanced glycated albumin induces macrophage apoptosis via activating caspase-12 pathway] [0.03%]
AGE诱导的巨噬细胞凋亡及其与Caspase-12活化的相关性研究
Jin-Guo Li,Qi Hao,Ying-Xue Liu et al.
Jin-Guo Li et al.
The purpose of the present study was to investigate the effect of advanced glycated albumin (AGE-alb) on the activation of caspase-12, a key molecule in endoplasmic reticulum stress (ERS)-associated apoptotic pathway, and to elucidate the u...
[Effect of secretin on the expression of cPLA2 and mPGEs-1 in mouse endometrial stromal cell during early pregnancy] [0.03%]
分泌素对小鼠早期妊娠子宫内膜间质细胞cPLA2和mPGEs-1表达的影响
Zhu Huang,Yi-Feng Ge,Jun Jing et al.
Zhu Huang et al.
Secretin, a gastrointestinal peptide, has been found to be expressed in mouse endometrial stromal cells (mESCs) during early pregnancy. In order to further investigate the function of secretin during embryo implantation, the expression leve...
[Progesterone-induced microRNA-1a inhibits the proliferation of endometrial epithelial cells] [0.03%]
孕酮诱导的miRNA-1a抑制子宫内膜上皮细胞增殖
Jun-Li Pan,Dong-Zhi Yuan,Li Nie et al.
Jun-Li Pan et al.
The aim of the present study was to investigate the effects of progesterone (P4)-induced microRNA-1a (miR-1a) on the proliferation of endometrial epithelial cells (EECs) and the underlying mechanism. In vivo, following subcutaneous injectio...
[Secondary hyperuricemia in chronic renal failure promotes vascular calcification in rats] [0.03%]
慢性肾功能衰竭大鼠原发性高尿酸血症促进血管钙化
Zhe Song,Yang Zhao,Xian Wang et al.
Zhe Song et al.
The present study was aimed to explore the effects of hyperuricemia on vascular calcification in chronic renal failure (CRF) and the mechanisms. Adenine diet-induced CRF rat model was used. Twenty-three male 8-week-old Wistar rats were rand...
Direct modulation of firing activity by dopamine D2 like receptors in the globus pallidus of both normal and parkinsonian rats [0.03%]
多巴胺D2样受体直接调节正常及帕金森氏病模型大鼠苍白球神经元放电活动
Yong-Cun Zhu,Yan Xue,Hui-Ling Diao et al.
Yong-Cun Zhu et al.
The globus pallidus occupies a critical position in the indirect pathway of the basal ganglia circuit, which regulates movement under both normal and pathological conditions. Previous studies have shown that the globus pallidus receives dop...
[Biological characteristics of mesenchymal stem cell and hematopoietic stem cell in the co-culture system] [0.03%]
共培养体系中骨髓间充质干细胞与造血干细胞的生物特性研究
Wei Wei,Chao Xu,Zhi-Yong Ye et al.
Wei Wei et al.
The aim of the present study was to obtain the qualified hematopoietic stem/progenitor cells (HSC/HPC) and human umbilical cord-mesenchymal stem cells (MSC) in vitro in the co-culture system. Cord blood mononuclear cells were separated from...
[Aliskiren inhibits proliferation of cardiac fibroblasts in AGT-REN double transgenic hypertensive mice in vitro] [0.03%]
阿利吉仑抑制AGT-REN双转基因高血压小鼠心房成纤维细胞增殖的作用研究
Li-Ping Wang,Su-Jing Fan,Shu-Min Li et al.
Li-Ping Wang et al.
The purpose of the present study is to explore the effect of aliskiren on the proliferation of cardiac fibroblasts (CFs) in AGT-REN double transgenic hypertensive (dTH) mice. The cultured CFs from AGT-REN dTH mice were divided into AGT-REN ...
Jing-Man Xu,Jin-Kun Xi,Zhe-Long Xu
Jing-Man Xu
The aim of the present study was to investigate the effect of zinc deficiency on cardiomyocyte survival and the underlying mechanisms. Simulated zinc deficiency model was developed in H9c2 cardiac cells with zinc chelator N, N, N', N'-tetra...
Mitochondrial division inhibitor Mdivi-1 ameliorates angiotensin II-induced endothelial dysfunction [0.03%]
线粒体分裂抑制剂Mdivi-1改善血管紧张素II所致的内皮功能障碍
Yu Chen,Jing-Rong Lin,Ping-Jin Gao
Yu Chen
Mitochondrial fission can occur via activation of dynamin-related protein 1 (Drp1), which participates in the mitochondrial membrane scission process. The present study was designed to investigate the effect of angiotensin II (AngII) on mit...