Systems specificity in responsiveness to intermittent artificial gravity during simulated microgravity in rats [0.03%]
模拟失重大鼠间歇性人工重力反应的系统特异性研究
Li-Fan Zhang,Shu Zhang
Li-Fan Zhang
It has been shown that the minimum gravity exposure requirements vary greatly among different physiological systems. A preliminary comparison between two extremes, vessels vs. bones, shows that not only the mechanostat at the tissue level d...
Yi-Zhang Chen
Yi-Zhang Chen
Although the modulation of synaptic activity plays an important role in the modulation of neuronal excitability, the significance of the ambient modulation (AM) of neuronal excitability should be emphasized. The AM refers to the alterations...
Yi-Xun Liu
Yi-Xun Liu
Follicular development and differentiation are sequential events which are tightly regulated by endocrine hormones, intraovarian regulators and cell-cell interactions. Balanced cell proliferation and apoptosis play an important role in the ...
Tao-Ling Bi,Jin-Jian Sun,Yu-Zi Tian et al.
Tao-Ling Bi et al.
Exosomes are nanosized small membrane microvesicles of endocytic origin secreted by most cell types. Exosomes, through its carrying protein or RNA from derived cells, affect gene regulation networks or epigenetic reorganization of receptor ...
Shuang-Ping Meng,Bei Ma
Shuang-Ping Meng
P2X7 receptors are closely associated with inflammation, and they have been found to be expressed on colonic cells broadly. In animal model of colonic inflammation, ATP/P2X7 signaling mainly promotes inflammation, and a variety of cells, in...
[Relationships of glucose transporter 4 with cognitive changes induced by high fat diet and glucose metabolism in hippocampus] [0.03%]
葡萄糖转运蛋白4在高脂饮食诱导的认知改变及海马区糖代谢中的作用关系研究
Yun-Li Zhang,Lin Wang
Yun-Li Zhang
The hippocampus not only plays a role in appetite and energy balance, but also is particularly important in learning and memory. Figuring out the relationships of hippocampal glucose transporter 4 (GLUT4) with hippocampal glucose metabolism...
Li-Ming Chen,Mei Liu,Ying Liu
Li-Ming Chen
Ion channels and transporters represent two major types of pathways of transmembrane transport for ions. Distinct from ion channels which conduct passive ionic diffusion, ion transporters mediate active transport of ions. In the perspective...
Bing Xu,Yu Zhang,Jiu-Lin DU
Bing Xu
Blood-brain barrier (BBB) precisely controls the material exchange between the blood and brain tissue, and plays a critical role in the maintenance of brain microenvironment homeostasis. Brain microvascular endothelial cells connect tightly...
[Establishment of an anesthesia model induced by etomidate in larval zebrafish] [0.03%]
[异丙酚诱导的斑马鱼麻醉模型的建立]
Wen-Jie DU,Jiu-Lin DU,Tian Yu
Wen-Jie DU
Despite the wide application of general anesthetic drugs in clinic, it is still unclear how these drugs induce the state of general anesthesia. Larval zebrafish has emerged as an ideal model for dissecting the mechanism of neural systems du...
[Serum amyloid A promotes the inflammatory response via p38-MAPK/SR-BI pathway in THP-1 macrophages] [0.03%]
[SAA通过p38 MAPK/SR-BI信号通路促进THP-1单核细胞的炎症反应]
Ming-Yan Zhu,Yan Wang,Yu Wang et al.
Ming-Yan Zhu et al.
To investigate the effect and mechanism of serum amyloid A (SAA) on the expression of scavenger receptor class B type I (SR-BI) and inflammatory response in THP-1 macrophages, the human THP-1 cells were treated with SAA and p38-MAPK agonist...