[Natriuretic peptide precursor C coding gene contributes to zebrafish angiogenesis] [0.03%]
心钠肽前体C基因参与斑马鱼的血管生成作用研究
Jing-Jing Zhang,Xin Wang,Dong Liu
Jing-Jing Zhang
This study aimed to investigate the expression of the natriuretic peptide precursor C coding gene nppc and its role in angiogenesis during embryonic period of the zebrafish. Whole mount in situ hybridization was performed to detect the expr...
[Comparison of agonists-induced contraction between main and the third-order branches of pulmonary arteries in rats] [0.03%]
大鼠肺动脉主干和三级分支血管张力比较研究
Qiu-Hong Huang,Yun-Ping Mu,Fu-Rong Yan et al.
Qiu-Hong Huang et al.
This study was designed to observe the differences between main pulmonary arteries and the third-order branches of pulmonary arteries in the contractile response to phenylephrine (Phen), endothelin-1 (ET-1) and potassium chloride (KCl). The...
Comparative Study
Sheng li xue bao : [Acta physiologica Sinica]. 2017 Feb 25;69(1):1-10. DOI: 2017
Yue-Chan Chen,Hong Wei,Zhi-Wei Zhang
Yue-Chan Chen
Krüppel-like factor 7 (KLF7), a member of Krüppel-like transcription factors (KLFs), also known as ubiquitous Krüppel- like factor (UKLF), is ubiquitously expressed in various tissues of adult human beings. Genetics reports showed that t...
Wen-Xiang Zhang,Si-Yu Chen,Chang Liu
Wen-Xiang Zhang
Mammals synchronize their circadian activity primarily to the cycles of light and darkness in the environment. Circadian rhythm is controlled by the central clock in the hypothalamic suprachiasmatic nucleus (SCN) and the peripheral clocks i...
[Research progress in signal bias of G protein-coupled receptor and its mechanism] [0.03%]
G蛋白偶联受体信号偏向性研究进展及其机制探讨
Pei-Bin Zhai,Lan Ma,Xing Liu
Pei-Bin Zhai
G protein-coupled receptors (GPCRs) mediate signal transduction via G protein or β-arrestin. Several biased ligands and receptors that preferentially signal through either G protein- or β-arrestin-mediated pathways have been identified. T...
[HIF-2α/Notch3 pathway mediates CoCl2-induced migration and invasion in human breast cancer MCF-7 cells] [0.03%]
缺氧诱导因子-2α/Notch3信号通路介导CoCl2诱导的人乳腺癌MCF-7细胞迁移和侵袭
Jian-Guo Wang,Lei Yuan
Jian-Guo Wang
The aim of this study is to investigate the effects of hypoxia inducible factor-2α (HIF-2α) and Notch3 on CoCl2-induced migration and invasion of human breast cancer cell line MCF-7. MCF-7 cells were exposed to normoxia (21% O2) or chemic...
[Temporal and spatial changes of α7nAChR and nNOS in cerebral cortex and hippocampus of Aβ-induced cognitive dysfunction rats] [0.03%]
阿霉素诱导认知功能障碍大鼠脑皮质和海马α7nAChR和nNOS的时空变化分布研究
Yan-Li Wang,Li-Xia Liu,Shao-Hu Wang et al.
Yan-Li Wang et al.
The present study was to explore the temporal and spatial distributions and variations of α7 nicotinic acetylcholine receptor (α7nAChR) and neuronal nitric oxide synthetase (nNOS) in cerebral cortex and hippocampus of Aβ-induced cognitiv...
[N-acetyl-L-cysteine reduces the ozone-induced lung inflammation response in mice] [0.03%]
[N-乙酰半胱氨酸减轻臭氧所致小鼠肺炎症反应]
Qing-Zi Chen,Zhao-Di Fu,Yu-Bo Zhou et al.
Qing-Zi Chen et al.
In this study, we investigated the protective effect of the antioxidant N-acetyl-L-cysteine (NAC) on the lung inflammation caused by ozone (O3) exposure in mice. Thirty-two C57BL/6 mice were randomly divided into control group, O3 group, O3...
[Effect of opioid receptors on acute stress-induced changes in recognition memory] [0.03%]
[阿片受体在急性应激源致识别记忆损害中的作用]
Ying Liu,Yu-Wei Wu,Zhao-Qiang Qian et al.
Ying Liu et al.
Although ample evidence has shown that acute stress impairs memory, the influences of acute stress on different phases of memory, such as acquisition, consolidation and retrieval, are different. Experimental data from both human and animals...
[Emodin ameliorates the peritoneal dialysis-related peritoneal fibrosis via inhibiting the activation of Notch pathway] [0.03%]
[蒽醌通过抑制Notch信号通路活化改善腹膜纤维化]
Hui-Chao Wang,Xu-Hong Lin,Xiao-Peng Fang et al.
Hui-Chao Wang et al.
Long term peritoneal dialysis (PD) is often associated with peritoneal fibrosis. The aim of this study was to explore the effect of emodin on PD-related peritoneal fibrosis and its related cellular and molecular mechanism. PD-related perito...