[VEGF enhances reconstruction of neurovascular units in the brain after injury] [0.03%]
vegf促进脑损伤后神经血管单元的重建
Zhi-Guang Pan,Ying Mao,Feng-Yan Sun
Zhi-Guang Pan
Vascular endothelial growth factor (VEGF) was originally recognized as a substance predominantly with vascular permeability and angiogenesis. Recently, more and more evidence indicated that VEGF is expressed in the neurons of the developing...
[Effects of tetramethylpyrazine on trigeminal neuralgia induced by chronic constriction injury of infraorbital nerve in rats] [0.03%]
藤菊素对慢性压迫损伤眶下神经诱发的大鼠三叉神经痛的作用及机制研究
Meng-Xia Tan,Wei Xiong,Ling-Kun He et al.
Meng-Xia Tan et al.
Trigeminal neuralgia (TN) is a kind of recurrent transient and severe pain that is limited to the trigeminal nerve in one or more branches. The clinical incidence of TN is high, which seriously affects the quality of life of the patients an...
[Quantitative evaluation of inhibitory effects of epileptic spikes on theta rhythms in the network of hippocampal CA3 and entorhinal cortex in patients with temporal lobe epilepsy] [0.03%]
［急性低氧性呼吸衰竭大鼠海马CA3区和内嗅皮质θ频段震荡网络抑制效应的量化评价］
Man-Ling Ge,Jun-Dan Guo,Sheng-Hua Chen et al.
Man-Ling Ge et al.
Epileptic spike is an indicator of hyper-excitability and hyper-synchrony in the neural networks. The inhibitory effects of spikes on theta rhythms (4-8 Hz) might be helpful to understand the mechanism of epileptic damage on the cognitive f...
[Effects of intrathecal administration of AM22-52 on mechanical allodynia and CCL2 expression in DRG in bone cancer rats] [0.03%]
AM22-52脊髓内给药对骨癌痛大鼠伤害性机械性.allodynia及DRG中CCL2表达的影响
Ya-Juan Chen,Yuan-Hui Huo,Yanguo Hong
Ya-Juan Chen
The pain peptide adrenomedullin (AM) plays a pivotal role in pathological pain. The present study was designed to investigate the effect of blockade of AM receptor on bone cancer pain (BCP) and its mechanism. BCP was developed by inoculatio...
[Generation and phenotype analysis of zebrafish mutations of obesity-related genes lepr and mc4r] [0.03%]
与肥胖相关的lepr和mc4r基因的斑马鱼突变体的构建及表型分析
Fei Fei,Shao-Yang Sun,Yu-Xiao Yao et al.
Fei Fei et al.
Obesity has become a severe public health problem across the world, and seriously affects the health and life quality of human beings. Here we generated lepr and mc4r mutant zebrafish via the CRISPR/Cas9 technique, and performed morphologic...
[Lipid-lowering effect of seven traditional Chinese medicine monomers in zebrafish system] [0.03%]
基于斑马鱼模型的七味中药单体降脂效应研究
Kan Chen,Chang-Qian Wang,Yu-Qi Fan et al.
Kan Chen et al.
The present study aimed to study lipid-lowering effect of seven traditional Chinese medicine monomers in zebrafish system. Zebrafish were fed with high fat diet to establish a hyperlipemia model, then fasted and bathed with seven traditiona...
[Role of TRPC6 in pulmonary artery smooth muscle cells proliferation and apoptosis under hypoxia and hypercapnia] [0.03%]
TRPC6在低氧及高碳酸血症诱导的大动脉平滑肌细胞增殖和凋亡中的作用机制研究
Xu-Guang Jia,Meng-Xiao Zheng,Jing-Jing Zhang et al.
Xu-Guang Jia et al.
The present study was to investigate the role of TRPC6 in pulmonary artery smooth muscle cells (PASMCs) proliferation and apoptosis under hypoxia and hypercapnia. PASMCs were isolated from chloral hydrate-anesthetized male Sprague-Dawley (S...
[Effects of salidroside on the secretion of inflammatory mediators induced by lipopolysaccharide in murine macrophage cell line J774.1] [0.03%]
牻牛儿醇苷对脂多糖诱导的小鼠巨噬细胞系J774.1炎性介质分泌的影响
Qian Huang,Xiao-Lan Hu
Qian Huang
To investigate the effect of salidroside (Sal) on the inflammatory activation of lipopolysaccharide (LPS)-induced murine macrophage cell line J774.1 and its possible mechanism, the cells were treated with PBS, LPS (0.5 µg/mL) or different ...
[Induction of robust senescence-associated secretory phenotype in mouse NIH-3T3 cells by mitomycin C] [0.03%]
mitomycin C诱导小鼠NIH-3T3细胞产生强力衰老相关分泌表型
Wei-Xing Huang,Xiao-Xuan Guo,Zhong-Zhi Peng et al.
Wei-Xing Huang et al.
Senescence-associated secretory phenotype (SASP) is often a concomitant result of cell senescence, embodied by the enhanced function of secretion. The SASP factors secreted by senescent cells include cytokines, proteases and chemokines, etc...
[Changes of perimysial junctional plates induced by excessive eccentric training and the effects of acupuncture intervention] [0.03%]
过度离心训练诱发肌内膜连接板重构及针刺干预效应
Mei Kong,Xiang Zhang,Mei-Ling Ye et al.
Mei Kong et al.
This study aimed to investigate the effects of acupuncture intervention on excessive eccentric training-induced changes of perimysial junctional plates (PJPs) domain. Thirty healthy male Wistar rats were randomly assigned to 5 groups: contr...