[Analyses of exercise-induced muscle damage-specific microRNA expression and molecular target of sarcolemmal damage in rats] [0.03%]
大鼠运动性肌肉损伤特异微小核糖核酸表达及肌膜损伤分子靶点分析
Yu-Ming Xu,Jian-Min Cao,Jun-Ping Li et al.
Yu-Ming Xu et al.
In the present study, we were to screen the specific microRNA (miRNA) of exercise-induced muscle damage (EIMD) and assess the EIMD-specific miRNAs-regulated target of sarcolemmal damage in rats. Twenty-four male Sprague-Dawley (SD) rats wer...
[Generation of tnnt2a knock-out zebrafish via CRISPR/Cas9 and phenotypic analysis] [0.03%]
CRISPR-Cas9生成tnnt2a敲除斑马鱼及表型分析
Lian Liu,Ran-Ran Zhang,Qian Yang et al.
Lian Liu et al.
Cardiac troponin T (cTnT) serves as a structural protein of myocardial fiber, and participates in heart excitation-contraction coupling process. Here, we generated tnnt2a (cTnT-coding gene) deletion mutant zebrafish via CRISPR/Cas9 techniqu...
Influence of sodium nitroprusside on expressions of FBXL5 and IRP2 in SH-SY5Y cells [0.03%]
NaNOPs对SH-SY5Y细胞FBXL5和IRP2表达的影响
Jie Wei,Yong Li,Qian Jiao et al.
Jie Wei et al.
Iron accumulation in the brain is associated with the pathogenesis of Parkinson's disease (PD). Misexpression of some iron transport and storage proteins is related to iron dyshomeostasis. Iron regulatory proteins (IRPs) including IRP1 and ...
[Different subtypes of estrogen receptor α and related signal molecules in the hippocampus are associated with spatial cognitive impairment of diabetic mice] [0.03%]
糖尿病小鼠海马不同亚型雌激素受体α及信号分子与空间认知障碍的关系
Ming-Rui Zhang,Chao Qu,Jia Sun et al.
Ming-Rui Zhang et al.
To study the correlation between the spatial cognitive impairment and different subtypes of estrogen receptor α (ERα) of hippocampus in diabetic mice, we used alloxan (intraperitoneal injection) to induce type 1 diabetes in male Kunming m...
[Optogenetic activation of dorsal hippocampal astrocytic Rac1 blocks the learning of associative memory] [0.03%]
光遗传激活海马Astrocyte细胞Rac1阻断关联记忆学习
Xiao-Mu Guo,Zhao-Hui Liao,Ye-Zheng Tao et al.
Xiao-Mu Guo et al.
Rac1 belongs to the family of Rho GTPases, and plays important roles in the brain function. It affects the cell migration and axon guidance via regulating the cytoskeleton and cellular morphology. However, the effect of its dynamic activati...
[Effect of high altitude hypoxia on fetal development during pregnancy and the reason analysis] [0.03%]
高原缺氧对妊娠期胎儿发育的影响及原因分析
Juan-Li Liu,Si-Qing Ma,Ta-Na Wuren
Juan-Li Liu
High altitude hypoxia is an important factor to affect fetal development during pregnancy. In the special environment, maternal physiological functions are regulated to maintain the maternal and fetal homeostasis, so that limited oxygen is ...
[Changes in biological functions of high-density lipoprotein after abnormal modification] [0.03%]
异常修饰对高密度脂蛋白生物学功能的影响
Hang Qu,Yang Yu,Shu-Cun Qin et al.
Hang Qu et al.
High-density lipoprotein (HDL) is composed of apolipoproteins, lipids and functional proteins. HDL protects against atherosclerosis (AS) by reverse cholesterol transport (RCT). HDL inhibits the lipid oxidation, inflammation and restores end...
Kai-Yu Xu,Fan Li
Kai-Yu Xu
Iron is an essential element for nervous system development, and maintaining a normal iron level in nervous system is controlled by multiple factors. Recent studies reported that iron dysregulation and the following iron metabolic pathways ...
Zi-Jian Tan,Shu-Hui Ju,Xiao Huang et al.
Zi-Jian Tan et al.
Glial cells, including astrocytes, oligodendrocyte progenitor cells (OPCs), NG2-glia, etc, are broadly distributed throughout the central nervous system (CNS). Also, it has been well known that glial cells play multi-roles in physiological ...
Oxytocin system in neuropsychiatric disorders: Old concept, new insights [0.03%]
神经精神疾病中的催产素系统：旧概念新见解
Afzal Misrani,Sidra Tabassum,Cheng Long
Afzal Misrani
Oxytocin (OXT) is a neuropeptide that plays a pivotal role among species peripherally and centrally. It recently has attracted much attention for its involvement in anxiety-related behavior, stress regulation, social behavior and various ne...