[Mechanisms of mitochondrial dynamics in ischemic stroke and therapeutic strategies] [0.03%]
[缺血性卒中线粒体动力学机制及治疗策略]
Xin-Yue Zheng,Ming Zhang,Kai-Qi Su et al.
Xin-Yue Zheng et al.
As a common neurological disease in China, stroke has an extremely high rate of death and disability, of which 80% is ischemic stroke (IS), causing a serious burden to individuals and society. Neuronal death is an important factor in the pa...
[The neurophysiological mechanisms of exercise-induced improvements in cognitive function] [0.03%]
运动改善认知功能的神经生理机制
Jian-Xiu Liu,Bai-Le Wu,Di-Zhi Wang et al.
Jian-Xiu Liu et al.
The neurophysiological mechanisms by which exercise improves cognitive function have not been fully elucidated. A comprehensive and systematic review of current domestic and international neurophysiological evidence on exercise improving co...
[Research progress on the effect of miRNA-mediated PPARγ-related signaling pathways on lipid metabolism in steroid-induced osteonecrosis of femoral head] [0.03%]
[miRNA介导的PPARγ相关信号通路影响糖皮质激素致股骨头坏死脂代谢的研究进展]
Hai-Yuan Gao,Xiao-Ping Wang,Ming-Wang Zhou et al.
Hai-Yuan Gao et al.
Steroid-induced osteonecrosis of femoral head (SONFH) is a disease characterized by femoral head collapse and local pain caused by excessive use of glucocorticoids. Peroxisome proliferator-activated receptor-γ (PPARγ) is mainly expressed ...
Shan-Shan Song,Hui-Ru Yang,Xiao-Li Yi et al.
Shan-Shan Song et al.
Cardiovascular diseases are the leading cause of mortality, posing a significant threat to human health due to the high incidence rate. Atherosclerosis, a chronic inflammatory disease, serves as the primary pathological basis for most such ...
[Roles and mechanisms of TRIM family proteins in the regulation of bone metabolism] [0.03%]
TRIM家族蛋白在骨代谢调控中的作用和机制
Jing Yang,Rui-Qi Huang,Ke Xu et al.
Jing Yang et al.
Tripartite motif-containing (TRIM) family proteins are crucial E3 ubiquitin ligases that have garnered significant attention for their regulatory roles in bone metabolism in recent years. This article reviews the function and regulatory mec...
[Hydrogen sulfide ameliorates hypoxic pulmonary hypertension in rats by inhibiting aerobic glycolysis-pyroptosis] [0.03%]
氢硫化氨通过抑制糖酵氧合-细胞死亡改善大鼠肺动脉高压现象研究
Yuan Cheng,Yun-Na Tian,Man Huang et al.
Yuan Cheng et al.
The present study aimed to explore whether hydrogen sulfide (H2S) improved hypoxic pulmonary hypertension (HPH) in rats by inhibiting aerobic glycolysis-pyroptosis. Male Sprague-Dawley (SD) rats were randomly divided into normal group, norm...
[Eccentric treadmill exercise promotes adaptive hypertrophy of gastrocnemius in rats] [0.03%]
eccentric运动促进大鼠比目鱼肌适应性肥大的作用
Zhi-Qiang Dai,Yu Ke,Yan Zhao et al.
Zhi-Qiang Dai et al.
The present study aimed to investigate the effects of eccentric treadmill exercise on adaptive hypertrophy of skeletal muscle in rats. Thirty-two 3-month-old Sprague Dawley (SD) rats were selected and randomly assigned to one of the four gr...
[Local overexpression of miR-429 sponge in subcutaneous white adipose tissue improves obesity and related metabolic disorders] [0.03%]
皮下白色脂肪组织局部过表达miR-429海绵改善肥胖及相关代谢紊乱
Liu Yao,Wen-Jing Xiu,Chen-Ji Ye et al.
Liu Yao et al.
Obesity is a worldwide health problem. An imbalance in energy metabolism is an important cause of obesity and related metabolic diseases. Our previous studies showed that inhibition of miR-429 increased the protein level of uncoupling prote...
[The immunomodulatory effect of berbamine on mice with systemic lupus erythematosus] [0.03%]
苦参碱对系统性红斑狼疮小鼠的免疫调节作用
Hui-Lian Wang,Jun-Ping Zhan,Xi-Yun Miao et al.
Hui-Lian Wang et al.
Systemic lupus erythematosus (SLE) is an autoimmune disease accompanied by various complications, and the exact etiology remains unclear. Treatments for SLE encompass hormone therapy, plasma exchange and immunoadsorption, and targeted biolo...
[Exercise preconditioning alleviates motor deficits in MPTP-induced Parkinsonian mice by improving mitochondrial function] [0.03%]
运动预适应通过改善线粒体功能缓解左旋高苯丙氨酸诱导的帕金森病小鼠的运动缺陷症状
Miao-Miao Xu,Dan-Ting Hu,Qiao Zhang et al.
Miao-Miao Xu et al.
Parkinson's disease (PD) is a common neurodegenerative disorder mainly related to mitochondrial dysfunction of dopaminergic neurons in the midbrain substantia nigra. This study aimed to investigate the effects of exercise preconditioning on...