[Research progress on neurobiological mechanisms of chronic postoperative pain] [0.03%]
慢性术后疼痛的神经生物学机制研究进展
Yi-Qin Wang,Wen-Jing Zhang,Wu-Jun Geng et al.
Yi-Qin Wang et al.
Postoperative pain is a common complication caused by surgical trauma. Epidemiological studies indicate that the incidence of moderate to severe acute postoperative pain ranges from 41% to 85%, with approximately 10% to 50% of patients pote...
[Progress on the mechanism of endocannabinoids involved in electroacupuncture for analgesia and itch relief] [0.03%]
[电针镇痛和止痒的内源大麻素机制研究进展]
Yu-Wei Cao,Ren-Jie Qin,Xiang-Hong Jing et al.
Yu-Wei Cao et al.
Chronic pain and pruritus are significant health challenges that pose major threats to human well-being, with existing therapeutic approaches being limited in their efficacy and scope. Electroacupuncture, as a therapy developed by combining...
[Neuroimmune mechanisms of lipocalin 2 in mediating chronic pain and itch] [0.03%]
神经免疫介质脂联素介导慢性疼痛和瘙痒的机制研究进展
Xia-Lin Cui,Shi-Yu Sun,Jun-Yi Ma et al.
Xia-Lin Cui et al.
Lipocalin 2 (LCN2), a member of the lipocalin superfamily, is expressed and secreted by various cells and functions as a transport protein for lipophilic small molecules such as steroids, lipopolysaccharides, iron and fatty acids. LCN2 play...
New insights into the pain of knee osteoarthritis: the characteristics of deep pain and abnormal central processing [0.03%]
膝骨关节炎疼痛的新见解：深部疼痛的特征及其中枢处理异常
Mu-Lan Chen,Yu-Qing DU,Bo-Yang Xu et al.
Mu-Lan Chen et al.
Knee osteoarthritis (KOA) represents one of the most common causes of chronic pain. The high prevalence and disability rates of KOA impose a severe burden on both individuals and society. In contrast to cutaneous pain, KOA-induced joint pai...
Mechanisms of cancer pain and the multitarget therapeutic potential of Traditional Chinese Medicine [0.03%]
癌症痛的机制及中医药多靶点治疗潜力
Guo-Qun Xu,Ying-Xin Tian,Guang-Yi Si et al.
Guo-Qun Xu et al.
Cancer pain is one of the most prevalent and debilitating symptoms in patients with advanced malignancies, arising from multifactorial mechanisms involving peripheral, central, and systemic pathways. Conventional analgesics, including opioi...
The dorsal root ganglion T-junction: a critical node in somatosensory processing and pain pathogenesis [0.03%]
背根神经节T型连接：感觉处理和疼痛发病机制中的关键节点
Zhi-He Zhang,Yun-Jie Fu,Yun Wang
Zhi-He Zhang
Pseudounipolar neurons in the dorsal root ganglia (DRG), as the central nodes of primary sensory afferents, possess a distinctive T-junction that is not merely a morphological peculiarity but also performs complex roles in rapid, multiplexe...
[Inhibition of O-GlcNAc transferase alleviates liver pathological changes in spontaneously obese mice] [0.03%]
抑制O-GlcNAc转移酶可缓解自发性肥胖小鼠肝病理变化
Zi-Yang Zhang,Xin-Yu Long,Jia-Yi Zhang et al.
Zi-Yang Zhang et al.
This study was to explore the effects of O-GlcNAc transferase (OGT) inhibition on the liver pathological changes in spontaneously obese mice. Ten 6-week-old male ob/ob mice were randomly divided into a control group and a drug-treated group...
[Treadmill exercise improves constipation in mice with chronic Parkinson's disease through activating autophagy] [0.03%]
跑步机运动通过激活自噬缓解慢性帕金森病模型小鼠便秘研究
Bi-Hui Nie,Yuan Gao,Xiao-Qian Liu et al.
Bi-Hui Nie et al.
This study aimed to explore the effects and molecular mechanisms of 8-week treadmill exercise on constipation symptoms in mice with chronic Parkinson's disease (PD). Forty C57BL/6 mice were randomly divided into four groups: control group, ...
[Reward value encoded by electrocorticography (ECoG) power spectrum in the prefrontal cortex] [0.03%]
前额叶电皮层记录(ECoG)功率谱的奖赏价值编码
Shen-Hua Lin,Yi-Hong Wang,Xu-Ying Xu et al.
Shen-Hua Lin et al.
Calculating reward value is a core component in the value-based decision-making process, where the brain guides behavioral choices by evaluating the reward values of different options. The prefrontal cortex (PFC), a central hub for higher-o...
[Hippocampal stereotactic injection of cerebrospinal fluid from single-prolonged stress mice induces PTSD-like behavior] [0.03%]
单侧延长应激小鼠脑脊液的海马立体定位注射诱发 PTSD 样行为
Ke-Ke Ding,Dao-Kang Chen,Shao-Jie Yang et al.
Ke-Ke Ding et al.
This study aimed to investigate the impact of cerebrospinal fluid (CSF) from single-prolonged stress (SPS) model mice on the neurobehavioral outcomes in normal mice, and to explore the underlying mechanisms. CSF was extracted from SPS mice ...