Yun-Fei Zhao,Yu-Hang Sun,Tai-Hua Jin et al.
Yun-Fei Zhao et al.
Selenoproteins, as the active form of selenium, play an important role in various physiological and pathological processes, such as anti-oxidation, anti-tumor, immune response, metabolic regulation, reproduction and aging. Although the expr...
[The impact of glycemic variability on diabetic complications and related mechanisms] [0.03%]
血糖波动与糖尿病并发症的关系及可能机制研究进展
Jing-Yi Liu,Qi An,Si-Qi Zhang et al.
Jing-Yi Liu et al.
Diabetes mellitus (DM) is a major global health issue, with glycated hemoglobin levels serving as the gold standard for evaluating glucose level control in DM patients. However, it has limitations in reflecting glucose oscillations (i.e. gl...
[Research progress on the comorbidity mechanism of sarcopenia and obesity in the aging population] [0.03%]
sarcopenia和肥胖的共病机制研究进展
Hao-Dong Tian,Yu-Kun Lu,Li Huang et al.
Hao-Dong Tian et al.
The increasing prevalence of aging has led to a rising incidence of comorbidity of sarcopenia and obesity, posing significant burdens on socioeconomic and public health. Current research has systematically explored the pathogenesis of each ...
[Research progress on the role of dopamine system in regulating hippocampal related brain functions] [0.03%]
多巴胺能系统调节海马相关脑功能的研究进展
Jing Ren,Wei-Yi Mo,Ling Wang et al.
Jing Ren et al.
Dopamine, as a catecholamine neurotransmitter widely distributed in the central nervous system, is involved in physiological functions such as motivation, arousal, reinforcement, and movement through various dopamine signaling pathways. The...
Qing Wang,Mei Liu,Zhang-Ji Dong
Qing Wang
As an important part of the cytoskeleton, microtubules play a crucial role in many cellular processes, such as cell division, intracellular transport, and maintaining cell morphology. The MAP1 family is an important family of microtubule-as...
Xiao-Juan Li,Bo Zheng,Ping Lan et al.
Xiao-Juan Li et al.
Alzheimer's disease (AD) is the commonest neurodegenerative disease that causes memory decline, cognitive dysfunction and behavior disorders in the aged people. Primary pathological hallmarks of AD include amyloid-β (Aβ), neurofibrillary ...
[Molecular mechanism of transcription factor PU.1 regulating erythroid differentiation and its role in hematological diseases] [0.03%]
转录因子PU.1调控红系分化的作用及机制及其在血液病中的作用
Zi-Jiang Yang,Dan Hu,Xiu-Juan Zhang
Zi-Jiang Yang
Transcription factor PU.1, as a core member of the ETS family, plays a pivotal role in the multi-lineage differentiation of hematopoietic stem cells, particularly in the regulation of erythroid differentiation. PU.1 orchestrates the process...
Targeting WEE1: a rising therapeutic strategy for hematologic malignancies [0.03%]
WEE1靶向：治疗血液系统恶性肿瘤的新兴策略
Hao-Bo Li,Thekra Khushafa,Chao-Ying Yang et al.
Hao-Bo Li et al.
Hematologic malignancies, including leukemia, lymphoma, and multiple myeloma, are hazardous diseases characterized by the uncontrolled proliferation of cancer cells. Dysregulated cell cycle resulting from genetic and epigenetic abnormalitie...
[Research progress on the protective effects of heat acclimation on the cardiova-scular system and its molecular mechanisms] [0.03%]
[热习服对心血管系统保护作用及机制研究进展]
Guo-Yu Li,Feng Guo,Zhuo Wang et al.
Guo-Yu Li et al.
Heat acclimation provides cardiovascular protection in high-temperature environments through multilevel mechanisms; however, the complete molecular basis of its effects remains unclear. In this paper, we systematically review the effects of...
[Exogenous administration of zinc chloride improves lung ischemia/reperfusion injury in rats] [0.03%]
氯化锌外源性给药改善大鼠肺缺血再灌注损伤
Shu-Yuan Wang,Jun-Peng Xu,Yuan Cheng et al.
Shu-Yuan Wang et al.
The aim of this study was to investigate the contribution of lung zinc ions to pathogenesis of lung ischemia/reperfusion (I/R) injury in rats. Male Sprague Dawley (SD) rats were randomly divided into control group, lung I/R group (I/R group...