[Ischemic post-conditioning alleviates I/R lung injury by activating PI3K/AKT pathway in rats] [0.03%]
缺血后处理通过激活PI3K/Akt信号通路减轻大鼠复灌肺损伤
Wang-Xin Yan,Yuan Cheng,Man Huang et al.
Wang-Xin Yan et al.
The present study aimed to investigate whether ischemic post-conditioning (I-post-C) could reduce lung ischemia/reperfusion injury (LIRI) by activating PI3K/AKT pathway in rats. Male Sprague-Dawley (SD) rats aged 6-8 weeks were randomly div...
[Spermine induces ferroptosis-related phenotype in acute myeloid leukemia cells through reactive oxygen species] [0.03%]
spermine通过活性氧诱导急性髓系白血病细胞发生铁死亡相关表型
Lu Wang,Dong-Wei Guan,Yao-Ying Long et al.
Lu Wang et al.
Polyamines, including putrescine, spermidine, and spermine, are widely involved in various physiological processes in vivo. Their metabolic alterations are closely associated with tumor development, and interfering with polyamine metabolism...
[Lactate clearance is positively correlated with peripheral blood monocyte counts after high-intensity exercise] [0.03%]
高强度运动后血乳酸清除率与外周血单核细胞计数呈正相关
Su-Jie Mao,Fan Xia,Jing-Feng Wang et al.
Su-Jie Mao et al.
This study aimed to explore the relationship between lactate clearance and immune function in elite athletes, providing a theoretical basis for optimizing training loads and immune monitoring. In this cross-sectional observational study, 31...
[The development trend of microRNA patents from the perspective of the Nobel Prize] [0.03%]
从诺贝尔奖视角看微小核糖核酸专利的发展趋势
Qiang-Yu Xiang,Zong-Zhen Wu,Lu Zhang et al.
Qiang-Yu Xiang et al.
The 2024 Nobel Prize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for their discovery of the central role of microRNA (miRNA) in gene regulation. Based on the Derwent Innovation patent database and combined wi...
[Exploring the regulatory mechanism of Sparassis latifolia polysaccharides on hepatic glucose metabolism disorders in mice based on transcriptomics] [0.03%]
基于转录组学的宽口榛孔菌多糖调节小鼠肝糖代谢障碍机制研究
Er-Chen Yang,Feng-Ying Jia,Li-Min Zhang et al.
Er-Chen Yang et al.
This study aimed to investigate the effects and mechanism of Sparassis latifolia polysaccharides (SLPs) on hepatic glucose metabolism disorders induced by a high-fat diet combined with streptozotocin (STZ) in mice. A mouse model of hepatic ...
[Effect of GLP-1 on MNCs activity in hypothalamic paraventricular nucleus in vitro in rats] [0.03%]
GLP-1对离体大鼠下丘脑室旁核MNCs活性的影响
Xin Jin,Li Chen,Chun-Ping Chu et al.
Xin Jin et al.
Glucagon-like peptide-1 (GLP-1) in the brain is synthesized by preproglucagon neurons and released through axonal projections to extensive regions such as the arcuate nucleus, hypothalamic paraventricular nucleus (PVN), rostral ventrolatera...
[ERβ-mediated estrogen signaling promotes the alleviation of inflammation and myofiber repair in cardiotoxin-induced acute skeletal myositis in mice] [0.03%]
[ERβ介导的雌激素信号促进卡蟾素诱导的小鼠急性骨骼肌炎的抗炎和肌纤维修复]
Jun-Yi Xie,Qi-Hui Cai,Xiao-Lu Niu et al.
Jun-Yi Xie et al.
Traumatic stress often leads to abnormalities in sex hormone levels, among which elevated estrogen levels are associated with improved patient prognosis. However, the mechanism by which estrogen affects the inflammatory response and repair ...
[Skeletal muscle-specific knockdown of ACSL1 gene ameliorates cisplatin-induced skeletal muscle atrophy] [0.03%]
骨骼肌特异性敲低ACSL1基因改善顺铂诱导的肌肉萎缩
Huan Wang,Hao-Zhe Wang,Jiang-Ping Xie et al.
Huan Wang et al.
The aim of this study was to explore the role of long-chain acyl-CoA synthetase 1 (ACSL1) in cisplatin-induced skeletal muscle atrophy and the underlying mechanism. Wild-type mice were divided into cisplatin group and control group. The res...
[Qizhiweitong particles improve the contractile phenotype of gastric smooth muscle cells in the Parkinson's disease rats with gastroparesis] [0.03%]
启志胃通颗粒改善帕金森病胃轻瘫大鼠胃平滑肌细胞收缩表型的作用研究
Yue Zhang,Xiao-Lin Xiu,Qian-Ying Shen et al.
Yue Zhang et al.
Parkinson's disease (PD) is often accompanied by symptoms of gastric dysmotility, such as gastroparesis. Gastroparesis not only seriously affects the life quality of PD patients, but also causes fluctuations in drug absorption rate, exacerb...
[Effects of repeated controlled ovarian stimulation on the expression of aerobic glycolysis-related enzymes at various stages of early embryo development in mice] [0.03%]
重复促排卵对小鼠胚胎发育不同阶段细胞有氧糖酵解相关酶表达的影响
Lu-Lu Shen,Bei-Bei Shi,Wen-Yan Xiong et al.
Lu-Lu Shen et al.
This study aims to investigate whether the reduction in early embryonic development due to repeated controlled ovarian stimulation (COS) is associated with the expression levels of enzymes related to aerobic glycolysis. A repeated COS mouse...