Real-Time analysis of exosome secretion of single cells with single molecule imaging [0.03%]
单分子成像对单细胞外泌体分泌的实时分析
Pengfei Zhang,Shaopeng Wang
Pengfei Zhang
The exosome-mediated response can promote or restrain the diseases by regulating the intracellular pathways, making the exosome become an effective marker for diagnosis and therapeutic control at the single-cell level. However, real-time an...
Aneuploidy: An Opportunity Within Single-Cell RNA Sequencing Analysis [0.03%]
单细胞RNA测序分析中的染色体非整倍性异常现象
Joe R Delaney
Joe R Delaney
Single-cell sequencing data has transformed the understanding of biological heterogeneity. While many flavors of single-cell sequencing have been developed, single-cell RNA sequencing (scRNA-seq) is currently the most prolific form in publi...
Visualization of integrin molecules by fluorescence imaging and techniques [0.03%]
荧光显微成像技术在整合素分子学研究中的应用进展
Chen Cai,Hao Sun,Liang Hu et al.
Chen Cai et al.
Integrin molecules are transmembrane αβ heterodimers involved in cell adhesion, trafficking, and signaling. Upon activation, integrins undergo dynamic conformational changes that regulate their affinity to ligands. The physiological funct...
Lokman Varisli
Lokman Varisli
The cell cycle is a conserved process from yeast to mammals and focuses on mechanisms that regulate the timing and frequency of DNA replication and cell division. The temporal and spatial expression of the genes is tightly regulated to ensu...
High passage numbers induce resistance to apoptosis in C2C12 muscle cells [0.03%]
高的传代次数使C2C12肌细胞产生对凋亡的抵抗性
Lucia Pronsato,Anabela La Colla,Ana Carolina Ronda et al.
Lucia Pronsato et al.
Cell lines with high passage numbers exhibit alterations in cell morphology and functions. In the present work, C2C12 skeletal muscle cells with either low (< 20) or high (> 60) passage numbers (identified as 1-C2C12 or h-C2C12, respectivel...
Autophagy, apoptosis and organelle features during cell exposure to cadmium [0.03%]
镉暴露诱导的细胞自噬、凋亡及细胞器特征研究进展
Cristiane dos Santos Vergilio,Edésio José Tenório de Melo
Cristiane dos Santos Vergilio
Cadmium (Cd) induces several effects in different tissues, but our knowledge of the toxic effects on organelles is insufficient. To observe the progression of Cd effects on organelle structure and function, HuH-7 cells (human hepatic carcin...
Creatine supplementation in trained rats causes changes in myenteric neurons and intestinal wall morphometry [0.03%]
creatine补充对训练大鼠的肌间神经元和肠壁形态的影响
Solange Marta Franzói De Moraes,Thais Andréia Brogio,Jacqueline Nelisis Zanoni et al.
Solange Marta Franzói De Moraes et al.
Creatine is widely used by athletes as an ergogenic resource. The aim of this study was to evaluate the influence of creatine supplementation on the duodenum of rats submitted to physical training. The number and myenteric neuronal cell bod...
Confocal laser scanning microscopy and immunohistochemistry of cerebellar Lugaro cells [0.03%]
小脑Lugaro细胞的共聚焦激光扫描显微镜和免疫组织化学研究
Orlando J Castejón
Orlando J Castejón
The present paper shows by means of confocal laser scanning microscopy the immunoreactivity of rat cerebellar Lugaro cells for calbindin, synapsin-I, PSD-95, GluR1, CaMKII alpha, and N-cadherin. Lugaro cells were easily characterized by the...
Post-treatment with plant extracts used in Brazilian folk medicine caused a partial reversal of the antiproliferative effect of glyphosate in the Allium cepa test [0.03%]
巴西民间医药中植物提取物的后处理部分逆转了Glyphosate在Allium cepa测试中的抗增殖作用
Viviane Dal-Souto Frescura,Andrielle Wouters Kuhn,Haywood Dail Laughinghouse th et al.
Viviane Dal-Souto Frescura et al.
Species of the genus Psychotria are used for multiple purposes in Brazilian folk medicine, either as water infusions, baths or poultices. This study was aimed to evaluate the genotoxic and antiproliferative effects of infusions of Psychotri...