PSTCNN: Explainable COVID-19 diagnosis using PSO-guided self-tuning CNN [0.03%]
基于PSO引导的自我调节卷积神经网络的可解释性COVID-19诊断（PSTCNN）
Wei Wang,Yanrong Pei,Shui-Hua Wang et al.
Wei Wang et al.
Since 2019, the coronavirus disease-19 (COVID-19) has been spreading rapidly worldwide, posing an unignorable threat to the global economy and human health. It is a disease caused by severe acute respiratory syndrome coronavirus 2, a single...
Navigating the genomic instability mine field of osteosarcoma to better understand implications of non-coding RNAs [0.03%]
通过探究非编码RNA在骨肉瘤基因组不稳定中的作用以期加深对非编码RNA的理解与认识
Kaniz Fatema,Zachary Larson,Jared Barrott
Kaniz Fatema
Osteosarcoma is one of the most genomically complex cancers and as result, it has been difficult to assign genomic aberrations that contribute to disease progression and patient outcome consistently across samples. One potential source for ...
The cellular microenvironment and cytoskeletal actin dynamics in liver fibrogenesis [0.03%]
肝纤维化中心质微环境及胞质细胞骨架肌动蛋白动力学研究进展
Nour Hijazi,Don C Rockey,Zengdun Shi
Nour Hijazi
Hepatic stellate cells (HSCs) are the primary effector cells in liver fibrosis. In the normal liver, HSCs serve as the primary vitamin A storage cells in the body and retain a "quiescent" phenotype. However, after liver injury, they transdi...
Weiyu Chen,Muhsin H Younis,Zhongkuo Zhao et al.
Weiyu Chen et al.
The knowledge of interactions among functional proteins helps researchers understand disease mechanisms and design potential strategies for treatment. As a general approach, the fluorescent and affinity tags were employed for exploring this...
Synergy of single-cell sequencing analyses and in vivo lineage-tracing approaches: A new opportunity for stem cell biology [0.03%]
单细胞测序分析与体内谱系示踪技术的协同作用——干细胞生物学的新机遇
Yuki Matsushita,Wanida Ono,Noriaki Ono
Yuki Matsushita
Single-cell sequencing technologies have rapidly progressed in recent years, and been applied to characterize stem cells in a number of organs. Somatic (postnatal) stem cells are generally identified using combinations of cell surface marke...
New paradigms in regenerative engineering: Emerging role of extracellular vesicles paired with instructive biomaterials [0.03%]
再生工程新范式：细胞外囊泡与指令型生物材料的新兴作用
W Benton Swanson,Yuji Mishina
W Benton Swanson
Mesenchymal stem cells (MSCs) have long been regarded as critical components of regenerative medicine strategies, given their multipotency and persistence in a variety of tissues. Recently, the specific role of MSCs in mediating regenerativ...
Margaret Simonian
Margaret Simonian
Pediatric central nervous system tumors are the most common tumors in children, it constitute 15%-20% of all malignancies in children and are the leading cause of cancer related deaths in children. Proteogenomics is an emerging field of bio...
Anti-lipid droplets accumulation effect of Annona montana (mountain soursop) leaves extract on differentiation of preadipocytes [0.03%]
安-nonann-montana叶提取物抑制前脂肪细胞分化中的脂滴累积作用
Ivy Leung,Maria-Luisa Veisaga,Margarita Espinal et al.
Ivy Leung et al.
The Annona genus is a member of Annonaceae, one of the largest families of plants across tropical and subtropical regions. This family has been used in several ethnomedicinal practices to treat a multitude of human diseases. However, the mo...
Petra Kraus,Ankita Samanta,Sina Lufkin et al.
Petra Kraus et al.
Pain and lifestyle changes are common consequences of intervertebral disc degeneration (IVDD) and affect a large part of the aging population. The stemness of cells is exploited in the field of regenerative medicine as key to treat degenera...
Implications of enolase in the RANKL-mediated osteoclast activity following spinal cord injury [0.03%]
脊髓损伤后enolase在RANKL介导的破骨细胞活性中的影响
Ramsha Shams,Naren L Banik,Azizul Haque
Ramsha Shams
Spinal Cord Injury (SCI) is a debilitating condition characterized by damage to the spinal cord, resulting in loss of function, mobility, and sensation. Although increasingly prevalent in the US, no FDA-approved therapy exists due to the un...