Georg T Wondrak,Elaine L Jacobson
Georg T Wondrak
Endogenous reactive intermediates such as photoexcited states of tissue chromophores, reactive oxygen species (ROS), reactive carbonyl species (RCS), and transition metal ions are mediators of tissue damage involved in initiation and progre...
Simonetta Friso,V Lotto,R Corrocher et al.
Simonetta Friso et al.
While overt vitamin B6 deficiency is not a frequent finding nowadays in medical practice, evidence suggests that insufficiency of this vitamin is rather widespread in a quite large portion of the population such as the elderly or in not unu...
Vitamins B6 and cancer [0.03%]
维生素B6与癌症关系研究进展
Sang Woon Choi,Simonetta Friso
Sang Woon Choi
Epidemiologic and laboratory animal studies have suggested that the availability of vitamin B6 modulates cancer risk. The means by which B6 mediates this effect is not known with any surety but it has been reported that high dietary vitamin...
Hilary J Powers,B M Corfe,E Nakano
Hilary J Powers
Riboflavin (7,8-dimethyl-10-ribitylisoalloxazine; vitamin B2) is a water-soluble vitamin, cofactor derivatives of which (FAD, FMN) act as electron acceptors in the oxidative metabolism of carbohydrate, amino acids and fatty acids and which ...
Derrick Lonsdale
Derrick Lonsdale
One of the earliest vitamins to be discovered and synthesized, thiamin was originally spelled with an "e". The terminal "e" was dropped when it was found that it was not an amine. It is still spelled with and without the "e" depending on th...
J D Williams,Elaine L Jacobson,H Kim et al.
J D Williams et al.
Skin, the largest, most exposed organ of the body, provides a protective interface between humans and the environment. One of its primary roles is protection against exposure to sunlight, a major source of skin damage where the UV radiation...
Folate-linked drugs for the treatment of cancer and inflammatory diseases [0.03%]
叶酸连接的药物在癌症和炎症性疾病治疗中的应用
Jun Yang,Erina Vlashi,Philip Low
Jun Yang
Folic acid, also known as vitamin B9 (Fig. 9.1), is an essential co-enzyme in one-carbon metabolism pathways, including the biosynthesis of nucleotides (i.e. purines, thymidine) and several amino acids. In general, two functionally differen...
Enzymatic and non-enzymatic antioxidative effects of folic acid and its reduced derivates [0.03%]
叶酸及其还原衍生物的酶促和非酶促抗氧化作用
Olaf Stanger,Willibald Wonisch
Olaf Stanger
A great part of the population appears to have insufficient folate intake, especially subgroups with higher demand, as determined through more sensitive methods and parameters currently in use. As the role of folate deficiency in congenital...
Anne M Molloy
Anne M Molloy
The vitamin folate functions within the cell as a carrier of one-carbon units. The requirement for one-carbon transfers is ubiquitous and all mammalian cells carry out folate dependent reactions. In recent years, low folate status has been ...
James M May
James M May
Vitamin C, or ascorbic acid, is important as an antioxidant and participates in numerous cellular functions. Although it circulates in plasma in micromolar concentrations, it reaches millimolar concentrations in most tissues. These high asc...