Asymmetry in sensory-motor function between the lower limbs in children with hemiplegic cerebral palsy: An observational study [0.03%]
儿童偏瘫性脑瘫患儿下肢感觉运动功能的不对称性：一项观察性研究
Hsiu-Ching Chiu,Louise Ada,Rong-Ju Cherng et al.
Hsiu-Ching Chiu et al.
The objective of this study was to examine the difference in sensory-motor impairments (i.e., balance, contracture, coordination, strength, spasticity, and sensation) between legs in children with hemiplegic cerebral palsy. An observational...
Observational Study
The Chinese journal of physiology. 2023 Sep-Oct;66(5):345-350. DOI:10.4103/cjop.CJOP-D-23-00057 2023
Klotho inhibits the activation of NLRP3 inflammasome to alleviate lipopolysaccharide-induced inflammatory injury in A549 cells and restore mitochondrial function through SIRT1/Nrf2 signaling pathway [0.03%]
Klotho通过SIRT1/Nrf2信号通路抑制NLRP3炎性小体活化以缓解LPS诱导的A549细胞炎症损伤并恢复线粒体功能
Yanjun Zeng,Gang Xu,Congrui Feng et al.
Yanjun Zeng et al.
Acute lung injury is a severe clinical condition constituting a major cause of mortality in intensive care units. This study aimed to investigate the role of klotho in alleviating lipopolysaccharide (LPS)-induced acute lung injury. LPS-indu...
A glutamatergic pathway between the medial habenula and the rostral ventrolateral medulla may regulate cardiovascular function in a rat model of post-traumatic stress disorder [0.03%]
缰核 medial habenula 和脑桥 rostral ventrolateral medulla 谷氨酸通路在创伤后应激障碍大鼠模型中调节心血管功能的作用机制研究
Ya-Yang Wu,Cheng-Hong Zeng,Kun-Yi Cai et al.
Ya-Yang Wu et al.
Post-traumatic stress disorder (PTSD) is a serious psychiatric disorder, and there is an association between it and the development of cardiovascular disease. The aim of this study was to explore whether there is a glutamatergic pathway con...
Daylily (Hemerocallis fulva Linn.) flowers improve sleep quality in human and reduce nitric oxide and interleukin-6 production in macrophages [0.03%]
黄蝉花改善人的睡眠质量并减少巨噬细胞中一氧化氮和白细胞介素-6的产生
Li-Min Hsu,Hua-Wei Chen,Po-Ching Wu et al.
Li-Min Hsu et al.
The flowers of daylily (Hemerocallis fulva Linn.) have been used as vegetable and medicinal herb for thousands of years in Taiwan and eastern Asia. Daylily flowers have been demonstrated to exert several biomedical properties. In this study...
Paricalcitol improved cardiac hypertrophy and fibrosis through upregulation of fibroblast growth factor-23 and downregulation of transforming growth factor-beta in a rat model of isoproterenol-induced cardiomyopathy [0.03%]
依普利酮通过上调成纤维细胞生长因子-23和下调转化生长因子-β在异丙肾上腺素诱导的心肌病大鼠模型中改善心脏肥大和纤维化
Chieh-Jen Wu,Yu-He Li,Hsin-Hung Chen
Chieh-Jen Wu
Acute cardiomyopathy is a significant global health concern and one of the leading causes of death in developed countries. Prior studies have shown an association between acute cardiomyopathy and low vitamin D levels. Although paricalcitol,...
LncRNA VPS9D1-AS1 regulates miR-187-3p/fibroblast growth factor receptor-like 1 axis to promote proliferation, migration, and invasion of prostate cancer cells [0.03%]
长链非编码RNA VPS9D1-AS1通过调节miR-187-3p/FGFRL1轴促进前列腺癌细胞增殖、迁移和侵袭
Chenguang Wu,Jian Chen,Dong Wang
Chenguang Wu
The morbidity and mortality of prostate cancer are increasing year by year, and the survival rate of prostate cancer patients after treatment is low. Therefore, investigating the molecular mechanism underlying prostate cancer is crucial for...
Genkwanin suppresses mitochondrial dysfunction to alleviate IL-1β-elicited inflammation, apoptosis, and degradation of extracellular matrix in chondrocytes through upregulating DUSP1 [0.03%]
genkwanin通过上调DUSP1来抑制软骨细胞中IL-1β诱导的炎症、凋亡和细胞外基质降解的线粒体功能障碍
Kanna Xu,Haoran Wang,Zhongqing Wu
Kanna Xu
Osteoarthritis (OA) is a form of chronic degenerative disease contributing to elevated disability rate among the elderly. Genkwanin is an active component extracted from Daphne genkwa possessing pharmacologic effects. Here, this study is de...
Knockdown of neurotrophin receptor-interacting melanoma-associated antigen homolog inhibits acute myeloid leukemia cell growth via the ERK pathway [0.03%]
神经rophilin受体相互作用黑色素瘤相关蛋白同源物的敲低通过ERK途径抑制急性髓系白血病细胞增殖
Hongxia Zhang,Guangsheng Wu,Beili Chen
Hongxia Zhang
Neurotrophin receptor-interacting melanoma-associated antigen homolog (NRAGE), a type II melanoma-associated antigen, plays a critical role in cell processes that are involved in the tumorigenesis of various cancers. However, the effect of ...
E2F8 knockdown suppresses cell proliferation and induces cell cycle arrest via Wnt/β-Catenin pathway in ovarian cancer [0.03%]
E2F8敲低通过Wnt/β-catenin途径抑制卵巢癌细胞增殖并诱导细胞周期停滞
Meiyin Zhang,Ye Xu,Yongjian Zhang et al.
Meiyin Zhang et al.
Ovarian cancer is one of the leading causes of death in female reproductive system cancers. However, the pathogenesis of ovarian cancer remains elusive. Our aim is to investigate the potential targets for ovarian cancer. Two microarray data...
Stomatin-like protein-2 contributes the migration and invasion of breast cancer cells via regulating ERK/FOXO3a signaling pathway [0.03%]
stomatin样蛋白-2通过调节ERK/FOXO3a信号通路促进乳腺癌细胞迁移和侵袭
Shengming Wu,Lingang Zhao,Qian Li
Shengming Wu
Breast cancer (BC) is the most common tumor in women, and its incidence is increasing, ranking first among female malignant tumors. It is urgently needed to find new and reliable biomarkers of BC and to understand the cellular changes that ...