The effect of long-term moderate exercise on myocardial metabolome in rats [0.03%]
长期中等强度运动对大鼠心肌代谢组的影响
Zheng Ping,Xiao Li Zhang,Zi Wen Wang et al.
Zheng Ping et al.
Regular moderate physical exercise is beneficial for the cardiovascular system. Our prior study has demonstrated a long-term moderate exercise (4-week of 60-min 74.0% V̇O2max treadmill running) is optimal in protecting from exhaustive exer...
Long non-coding RNA NBR2 suppresses the progression of colorectal cancer by downregulating miR-19a to regulate M2 macrophage polarization [0.03%]
长链非编码RNA NBR2通过下调miR-19a调节M2巨噬细胞极化来抑制结直肠癌的发展进程
Xiaoting Yang,Ye Luo,Mengying Li et al.
Xiaoting Yang et al.
Colorectal cancer (CRC) is a malignant tumor of the gastrointestinal tract that significantly impacts the health of patients and lacks promising methods of diagnosis. Tumor-associated macrophages (TAMs) are involved in CRC progression, and ...
Anti-oncogenic mechanism of KLF17 in colon cancer by repressing cell migration and invasion via FHL1 upregulation [0.03%]
KLF17通过上调FHL1抑制细胞迁移和侵袭来抑制结肠癌的抗肿瘤机制
Shengen Yi,Ming Luo,Yanjin Peng et al.
Shengen Yi et al.
Colon cancer is a disease with high prevalence worldwide. This study sought to investigate Kruppel-like factor 17 (KLF17) mechanism in the development of colon cancer through four-and-a-half-LIM domain protein 1 (FHL1). In colon cancer cell...
Effects of electroacupuncture combined with acupoint catgut embedding on gastrointestinal motility and gastrointestinal hormones in rats with functional dyspepsia [0.03%]
电针结合穴位埋线对功能性消化不良大鼠胃肠动力及胃肠激素的影响
Hui Yu,Huiqian Deng,Wei Zhou et al.
Hui Yu et al.
Electroacupuncture (EA) or acupoint catgut embedding (ACE) plays a therapeutic role in functional dyspepsia (FD). Herein, we aimed to elucidate the influences of EA combined with ACE on gastrointestinal motility and gastrointestinal hormone...
Irbesartan eases lipopolysaccharide-induced lung injury In Vitro and In Vivo [0.03%]
伊贝沙坦缓解脂多糖所致的肺损伤的体内外研究
Zhongyuan Zhang,Wei Wang
Zhongyuan Zhang
Acute lung injury (ALI) is classified as a devastating pulmonary disorder contributing to significant incidence and fatality rate. Irbesartan (IRB) is an angiotensin II receptor blocker that has been proposed to protect against oleic acid-i...
Parkin enhances sensitivity of paclitaxel to nasopharyngeal carcinoma by activating BNIP3/NIX-mediated mitochondrial autophagy [0.03%]
Parkin通过激活BNIP3/NIX介导的线粒体自噬增强鼻咽癌对紫杉醇的敏感性
Haifeng Ni,Renhui Liu,Zhen Zhou et al.
Haifeng Ni et al.
As a malignant head and neck cancer, nasopharyngeal carcinoma (NPC) has high morbidity. Parkin expression has been reported to be reduced in NPC tissues and its upregulation could enhance paclitaxel-resistant cell cycle arrest. This study w...
Ophiopogonin D improves oxidative stress and mitochondrial dysfunction in pancreatic β cells induced by hydrogen peroxide through Keap1/Nrf2/ARE pathway in diabetes mellitus [0.03%]
Ophiopogonin D通过Keap1/Nrf2/ARE通路改善糖尿病诱导的过氧化氢引起的胰岛β细胞氧化应激和线粒体功能障碍
Hongyan Zhang,Xuezhi Kang,Jun Ruan et al.
Hongyan Zhang et al.
Diabetes mellitus (DM) is a metabolic disease characterized by high blood sugar. Due to its complex pathogenesis, no effective drugs have been found so far. Ophiopogonin D (OP-D) has anti-inflammatory, antioxidant, and anticancer activities...
Beta-hydroxy-beta-methylbutyrate supplementation preserves fat-free mass in collegiate boxers during acute body mass loss [0.03%]
β-羟基-β-甲基丁酸补充剂在急性体重降低期间保持大学生拳击手的无脂体重
Chen-Kang Chang,Shih-Yen Kao,Chung-Yuan Wang
Chen-Kang Chang
Acute body mass loss before competitions in combat sports usually leads to loss in fat-free mass. Beta-hydroxy-beta-methylbutyrate (HMB) has been shown to increase skeletal muscle mass and muscle strength in various muscle wasting condition...
Randomized Controlled Trial
The Chinese journal of physiology. 2023 Nov-Dec;66(6):485-493. DOI:10.4103/cjop.CJOP-D-23-00074 2023
Long non-coding RNA LINC00565 regulates ADAM19 expression through sponging microRNA-532-3p, thereby facilitating clear cell renal cell carcinoma progression [0.03%]
长链非编码RNA LINC00565通过吸附microRNA-532-3p调节ADAM19表达，从而促进透明细胞肾细胞癌进展
Bin Meng,Pengfei Wang,Chaofei Zhao et al.
Bin Meng et al.
Proven by publications, long non-coding RNAs (lncRNAs) play critical roles in the development of clear cell renal cell carcinoma (ccRCC). Although lncRNA LINC00565 has been implicated in the progression of various cancers, its biological ef...
ADAMTS13 inhibits H2O2-induced human venous endothelial cell injury to attenuate deep-vein thrombosis by blocking the p38/ERK signaling pathway [0.03%]
ADAMTS13通过阻断p38/ERK信号通路抑制H2O2诱导的人静脉内皮细胞损伤从而减轻深静脉血栓形成
Guangfeng Zheng,Qiang Zhang,Chuanyong Li et al.
Guangfeng Zheng et al.
Deep vein thrombosis (DVT) is a common complication in hematologic malignancies and immunologic disorders. Endothelial cell injury and dysfunction comprise the critical contributor for the development of DVT. A disintegrin and metalloprotei...