Sevoflurane attenuates proliferative and migratory activity of lung cancer cells via mediating the microRNA-100-3p/sterol O-Acyltransferase 1 axis [0.03%]
七氟醚通过调节microRNA-100-3p/甾醇O-酰基转移酶1轴削弱肺癌细胞的增殖和迁移活性
Bicheng Fu,Fucheng Zhou,Jian Zhang et al.
Bicheng Fu et al.
Recently, evidence has shown that microRNA-100-3p (miR-100-3p) has been revealed as a tumor suppressor in diverse human diseases, while its capability in lung cancer warrants further validation. In this work, we aimed to discuss the impact ...
Impacts of delta 9-tetrahydrocannabinol against myocardial ischemia/reperfusion injury in diabetic rats: Role of PTEN/PI3K/Akt signaling pathway [0.03%]
九氢大麻醇通过PTEN/PI3K/Akt信号通路对糖尿病心肌缺血再灌注损伤的影响
Xiaohua Zhao,Zhao Gao,Wenbin Wen et al.
Xiaohua Zhao et al.
Despite the current optimal therapy, patients with myocardial ischemia/reperfusion (IR) injury still experience a high mortality rate, especially when diabetes mellitus is present as a comorbidity. Investigating potential treatments aimed a...
Icariside II suppresses ferroptosis to protect against MPP+-Induced Parkinson's disease through Keap1/Nrf2/GPX4 signaling [0.03%]
伊卡洛宁II通过Keap1/Nrf2/GPX4信号抑制铁死亡以保护MPP+-诱导的帕金森病
Wenbo Fan,Jianwu Zhou
Wenbo Fan
Parkinson's disease (PD) is recognized as a degenerative and debilitating neurodegenerative disorder. The novel protective role of icariside II (ICS II) as a plant-derived flavonoid compound in neurodegenerative diseases has aroused much at...
The pan-liver network theory: From traditional chinese medicine to western medicine [0.03%]
泛肝网理论：从中医到西医
Yaxing Zhang,Xian-Ming Fang
Yaxing Zhang
In traditional Chinese medicine (TCM), the liver is the "general organ" that is responsible for governing/maintaining the free flow of qi over the entire body and storing blood. According to the classic five elements theory, zang-xiang theo...
Partner of NOB1 homolog transcriptionally activated by E2F transcription factor 1 promotes the malignant progression and inhibits ferroptosis of pancreatic cancer [0.03%]
E2F转录因子1诱导的NOB1同源物转录激活伙伴通过促进恶性进展和抑制铁死亡作用于胰腺癌
Qin Yang,Bin Yang,Min Chen
Qin Yang
Pancreatic cancer (PC) is one of the deadliest malignancies. Partner of NOB1 homolog (PNO1) has been reported to be involved in tumorigenesis. However, the role of PNO1 in PC remains to be elucidated. The purpose of this study was to examin...
PRPF19 promotes the proliferation, migration, and inhibits autophagy in prostate cancer by suppressing SLC40A1 [0.03%]
PRPF19通过抑制SLC40A1促进前列腺癌细胞的增殖、迁移并抑制自噬
Guofei Zhang,Wansong Zhang,Mingjiang Dan et al.
Guofei Zhang et al.
Prostate cancer (PCa) is a common cancer and the leading cause of cancer-related death in men. To investigate the role of pre-mRNA processing factor 19 (PRPF19) in proliferation, migration of PCa, and evaluate the potential ability of PRPF1...
ZWINT promotes the proliferation, migration, and invasion of cervical cancer cells by regulating the p53/p21 signaling pathway [0.03%]
ZWINT通过调节p53/p21信号通路促进宫颈癌细胞的增殖、迁移和侵袭
Zhe Ma,Yufei Cai,Chenchen Tian
Zhe Ma
Cervical cancer leads to 300,000 deaths annually and the mechanism of cervical carcinogenesis remains unclear. Zeste White 10-interacting kinetochore protein (ZWINT) is uniquely elevated in malignancies, promoting proliferation, migration, ...
SPAG5 promotes the proliferation, migration, invasion, and epithelial-mesenchymal transformation of colorectal cancer cells by activating the PI3K/AKT signaling pathway [0.03%]
SPAG5通过激活PI3K / AKT信号通路促进结直肠癌细胞的增殖，迁移，侵袭和上皮间质转化
Xuelian Zhang,Weiyu Wu,Xiaohui Li et al.
Xuelian Zhang et al.
Colorectal cancer (CRC) is a cancer that occurs in the rectum or colon with a high incidence. Sperm-associated antigen 5 (SPAG5), a gene that regulates cell division, has been observed highly expressed in a variety of cancers, but its role ...
Correlation between serum beta-human chorionic gonadotropin levels and thyroid metabolic function in pregnant women with hyperemesis gravidarum [0.03%]
妊娠剧吐患者血清β-HCG水平与甲状腺代谢功能的相关性研究
Haiyan Zheng,Qian Wang,Feng Chen
Haiyan Zheng
As previously demonstrated, serum beta-human chorionic gonadotropin (β-hCG) is linked to identifying early gestational abnormalities. This research was aimed at investigating the correlation between serum β-hCG levels and thyroid metaboli...
Reducing myocardial infarction by combination of irisin and Dendrobium nobile Lindl through inhibiting nod-like receptor protein-3-related pyroptosis and activating PINK1/Parkin-mitophagy during aging [0.03%]
通过抑制NLRP3相关炎性小体介导的细胞焦亡和激活PINK1/Parkin线粒体自噬减少衰老过程中的心肌梗死损伤：irisin与石斛搭配使用的效果
Chen Ding,Chaofeng Zhang
Chen Ding
Aging, a crucial risk factor for ischemic heart disease, has negative impacts on cardioprotective mechanisms. As such, there is still an unmet requirement to explore potential therapies for improving the outcomes of myocardial ischemia/repe...