Zhiqiang Hu,Jingling Pan,Jialing Wang et al.
Zhiqiang Hu et al.
Breast cancer is one of the most common malignant tumors in women worldwide. Surgery, chemotherapy, and targeted drugs are the main methods currently used in clinical treatment of breast cancer. Although they can improve the symptoms of pat...
Epoxyeicosatrienoic acids and soluble epoxide hydrolase in physiology and diseases of the central nervous system [0.03%]
epoxyeicosatrienoic acids和可溶性环氧化物水解酶在中枢神经系统的生理和疾病中的作用
Yi-Min Kuo,Yi-Hsuan Lee
Yi-Min Kuo
Epoxyeicosatrienoic acids (EETs) are fatty acid signaling molecules synthesized by cytochrome P450 epoxygenases from arachidonic acid. The biological activity of EETs is terminated when being metabolized by soluble epoxide hydrolase (sEH), ...
The predictive and prognostic role of hematologic and biochemical parameters in the emergency department among coronavirus disease 2019 patients [0.03%]
急诊科血细胞和生化指标在新型冠状病毒肺炎患者中的预测及预后价值分析
Chun-Yen Huang,Huang-Wen Tsai,Chia-Ying Liu et al.
Chun-Yen Huang et al.
Coronavirus disease 2019 (COVID-19) had caused a worldwide pandemic with public health emergencies since 2020. For the symptomatic patients, high mortality rate was observed if without timely and optimized management. In this study, we aime...
The risk stratification of coronary vascular disease as linked to homocysteine, its modulating genes, genetic polymorphisms, conventional predictors, and with antihypertensive medicaments [0.03%]
同型半胱氨酸、其调节基因及遗传多态性、常规预测指标以及抗高血压药物与冠状血管病的风险分层的关系
Rizwan Masud,Aiman Farogh Anjum,Muhammad Zeeshan Anwar et al.
Rizwan Masud et al.
Cardiovascular disease (CVD) have multifactorial nature, and owing to their disparate etiological roots, it is difficult to ascertain exact determinants of CVD. In the current study, primary objective was to determine association of single ...
Lipotoxicity in human lung alveolar type 2 A549 cells: Mechanisms and protection by tannic acid [0.03%]
单宁酸对脂毒性诱导的肺泡II型A549细胞损伤的保护作用及机制研究
Kun-Feng Tsai,Chen-Jung Shen,Chi-Wai Cheung et al.
Kun-Feng Tsai et al.
Palmitic acid (PA) is a saturated free fatty acid which, when being excessive, accounts for lipotoxicity. Using human lung A549 cells as a model for lung alveolar type 2 epithelial cells, we found that challenge of A549 cells with PA result...
A study of the cardioprotective effect of spermidine: A novel inducer of autophagy [0.03%]
腐胺的心脏保护作用研究：自噬的新诱导因素
Eman Magdy Omar,Rasha Said Omar,Mai Said Shoela et al.
Eman Magdy Omar et al.
Acute myocardial infarction (AMI) is an instant death of cardiomyocytes that ends in a large mortality worldwide. Thus, there is a great interest to come up with novel protective approaches for AMI to mount cardiomyocyte survival, enhance p...
Vasorelaxation effect of oxysophoridine on isolated thoracicc aorta rings of rats [0.03%]
氧化Sophoridine对大鼠分离主动脉环的血管松弛效应
Nan Li,Yefeng Chen,Yanmin Pei et al.
Nan Li et al.
Oxysophoridine (OSR) is a main active alkaloid extracted from Sophora alopecuroides, which is a traditional Chinese herbal medicine that has been used widely. In this study, we used thoracic aorta rings isolated from Sprague-Dawley rats to ...
Nicotinamide adenine dinucleotide promotes synaptic plasticity gene expression through regulation N-methyl-D-aspartate receptor/Ca2+/Erk1/2 pathway [0.03%]
烟酰胺腺嘌呤二核苷酸通过调控N-甲基-D-天冬氨酸受体/钙离子/Erk1/2通路促进突触可塑性相关基因表达
Xiao-Yu Liu,Rui-Heng Song,Tao Li et al.
Xiao-Yu Liu et al.
Nicotinamide adenine dinucleotide (NADH) has been reported to regulate synaptic plasticity recently, while its role in this process remains unclear. To explore the contribution and the underlying mechanisms of NADH regulating synaptic plast...
Chia-Bao Chu,Chao-Chun Yang,Shaw-Jenq Tsai
Chia-Bao Chu
Hidradenitis suppurativa is a cutaneous chronic inflammatory disease that is estimated to affect about 1% of the population and caused pain, malodorous discharge, disfigurement, and poor quality of life with psychosocial problems. The typic...
Heat shock protein 90α in nipple discharge as a potential tumor marker for breast cancer [0.03%]
乳头溢液中热休克蛋白90α可作为乳腺癌的肿瘤标志物
Yan-Yan Wang,Can Liu,Xu Chen et al.
Yan-Yan Wang et al.
Heat shock protein 90α (HSP90α) has been confirmed to be upregulated in the blood in various types of tumors and may therefore serve as a potential tumor marker. However, whether HSP90α exists in nipple discharge remains unknown, and its...