Results of immunocytochemical, neurochemical, and behavioral studies in aluminum-induced neurofilamentous degeneration [0.03%]
铝诱导的神经丝变性的免疫细胞化学、神经化学和行为学研究结果
W W Pendlebury,M F Beal,N W Kowall et al.
W W Pendlebury et al.
We undertook a series of experiments designed to further characterize behavioral, neurochemical and immunocytochemical features of aluminum neurotoxicity in the rabbit. Aluminum-exposed rabbits developed learning and memory deficits which w...
J Ulrich,B H Anderton,J P Brion et al.
J Ulrich et al.
The first half of this paper is devoted to a review on the cytoskeletal immunocytochemistry of the various morphological changes in Alzheimer's disease (AD), i.e. neurofibrillary tangles (NFT), senile plaques (SP), granulovacuolar degenerat...
W T Nickell,M T Shipley
W T Nickell
We have used the cholinergic projection from the nucleus of the horizontal limb of the diagonal band (HDB) to the olfactory bulb as a model for studying the neurophysiology of cholinergic projections from the basal forebrain to cortical str...
Comparison of rates of progression in Alzheimer's disease and Parkinson's disease [0.03%]
阿尔茨海默病和帕金森病进展速度的比较
T J Rosen,J H Growdon,S Corkin
T J Rosen
In order to compare the progression of memory impairments in Parkinson's disease (PD) and Alzheimer's disease (AD), we administered the Memory and Information section of the Blessed Dementia Scale (BDS) at least twice to 33 patients with PD...
Comparative Study
Journal of neural transmission. Supplementum. 1987:24:105-7. DOI: 1987
J A Mortimer,S P Jun,M A Kuskowski et al.
J A Mortimer et al.
Sixty patients with Parkinson's disease were administered a battery of neuropsychological tests. Using regression data from a matched normal control sample, age- and education-residualized test scores were obtained for the patients. Three c...
A Albanese,M C Altavista,P Rossi
A Albanese
In the present paper the organization of central nervous system dopaminergic pathways is concisely reviewed. Six dopaminergic systems are described: the midbrain efferent system, the tubero-infundibular, the diencephalo-spinal, the incerto-...
Problems in daily motor performances in Parkinson's disease: the continuous dopaminergic stimulation [0.03%]
帕金森病患者日常运动表现的问题：持续多巴胺能刺激的作用
F Stocchi,S Ruggieri,G Brughitta et al.
F Stocchi et al.
Fluctuations in motor performances are the major problem in the longterm management of Parkinson's disease. In this study the clinical effects of L-dopa intravenous infusion were evaluated in 18 parkinsonian patients with fluctuations. 14 o...
L Battistin,F Bracco,M Saladini
L Battistin
Levodopa is the most useful drug for treatment of Parkinson's disease today, even if a progressive decline of therapeutic activity with the appearance of important side affects is a well known feature of the long-term levodopa therapy. Here...
F Girotti,R Marano,L Grazzi et al.
F Girotti et al.
Neuropsychologic studies on Parkinson's disease have shown an impairment of specific cognitive functions and a greater evidence of dementia. Cognitive alterations are related to the gravity of some peculiar motor symptoms of the disease and...