Urinary Dickkopf-3 reflects renal and vascular damage in diabetic kidney disease: A cross-sectional study [0.03%]
尿液DKK-3在糖尿病肾脏疾病中反映肾脏和血管损伤:一项横断面研究
Merve Oruc,İsmail Baloglu,Mehmet Burak Erçin et al.
Merve Oruc et al.
Background: Dickkopf-3 (DKK3) is a stress-induced glycoprotein involved in Wnt/β-catenin signaling and has emerged as a marker of renal tubular injury and fibrosis. Although urinary DKK3 has been associated with kidney d...
Network pharmacology and experimental verification reveal the mechanism of hederagenin in suppressing podocyte injury in focal segmental glomerular sclerosis [0.03%]
网络药理学与实验验证揭示白桦脂醇抑制局灶节段性肾小球硬化系膜细胞增殖的机制
Xiyue Tian,Rangyue Han,Xiaojiao Gu et al.
Xiyue Tian et al.
Background: Podocyte injury is a pivotal driver of chronic kidney disease (CKD) progression in focal segmental glomerulosclerosis (FSGS). Although hederagenin (HDG) has shown promise in the treatment of CKD, its specific ...
EASIX in medical ICU: Chloride-modified RRT risk and associations with mortality and length of stay [0.03%]
改良的连续性肾脏替代疗法中氯化物与ICU病死率及住院时间的关系研究
Ali Zeynettin,Orhan Balikci,İsmail Demir
Ali Zeynettin
Background: Endothelial activation and microvascular dysfunction are implicated in organ injury in critical illness, yet the prognostic value of the Endothelial Activation and Stress Index (EASIX) may vary across heteroge...
Rituximab improves the control of pediatric nephrotic syndrome and reduces healthcare utilization [0.03%]
利妥昔单抗可改善儿童肾病综合征的控制并减少医疗保健利用
Ahmed Zeid,Melonie Phillips,Christine Sethna et al.
Ahmed Zeid et al.
Background: Rituximab (RTX) is often used in children with nephrotic syndrome (NS), but there is lack of consensus on its dose among pediatric nephrologists. This study aimed to assess its efficacy in controlling NS and i...
Telitacicept combined with glucocorticoids in adult-onset IgA vasculitis nephritis: A case report [0.03%]
telitacicept联合糖皮质激素治疗成人起病IgA血管炎肾损害一例报告
Shunian Guo,Meng He,Hanyu Meng et al.
Shunian Guo et al.
Aims: IgA vasculitis with nephritis (IgAVN), a severe renal manifestation of IgA vasculitis, is rare in adults and associated with high morbidity. Current therapies are suboptimal, highlighting the need for novel approach...
Systematic review of risk prediction models for autogenous arteriovenous fistula dysfunction in maintenance hemodialysis patients [0.03%]
维持性血液透析患者自体动静脉内瘘功能不良风险预测模型的系统评价
Ping Liu,Dan Zhu,Huimin Mao
Ping Liu
Objective: To systematically evaluate existing risk prediction models for autogenous arteriovenous fistula (AVF) dysfunction in maintenance hemodialysis (MHD) patients, in order to provide a reference for clinical practic...
Composite dietary antioxidant index in predicting chronic kidney disease risk: Findings from NHANES 1999 - 2018 [0.03%]
基于NHANES(1999-2018)数据的复合膳食抗氧化指数与慢性肾病发病风险预测关系的研究
Weiwei Li,Linsen Jiang,Sixia Chen et al.
Weiwei Li et al.
Background: Chronic kidney disease (CKD) poses a significant global health burden, with oxidative stress implicated in its pathogenesis. The composite dietary antioxidant index (CDAI), integrating multiple dietary antioxi...
Clinical characteristics and outcomes of adults with minimal change disease: A retrospective, cross-sectional study [0.03%]
成人微小病变型肾病的临床特征及预后状况:回顾性横断面研究
Fan Zhang,Xun Luo,Hailang Xiao
Fan Zhang
Minimal change disease (MCD) is a common cause of nephrotic syndrome in adults, with limited evidence available on its treatment and prognosis. In this study, we retrospectively included the clinical characteristics and treatment results of...
DeJian Ma,Yi Wei,XiaoJing Hu et al.
DeJian Ma et al.
Objective: The complex pathophysiological mechanism of end-stage renal disease (ESRD) has not been fully understood. Cuproptosis is a newly discovered type of programmed cell death. Therefore, this study attempts to clari...
The relationship between red cell distribution width and platelet ratio in acute kidney injury among ventilator-associated pneumonia patients: A MIMIC-IV database study [0.03%]
红细胞分布宽度与急性肾损伤通气相关性肺炎患者的血小板比率之间的关系:一项MIMIC-IV数据库研究
Ye Song,Minling Li,AQiao Sun et al.
Ye Song et al.
Background: Acute kidney injury (AKI) is a common sequela of ventilator-associated pneumonia (VAP), further complicating patient care and outcomes. The red cell distribution width-to-platelet ratio (RPR), an established m...