Therapeutic Potential of the Genus Zanthoxylum Phytochemicals: A Theoretical ADME/Tox Analysis [0.03%]
木兰属药用植物的药物潜力：理论ADME/tox分析
Emily N Wekesa,Njogu M Kimani,Sarah N Kituyi et al.
Emily N Wekesa et al.
Natural products (NPs) are essential in the search for new drugs to treat a wide range of diseases, including infectious and malignant disorders. However, despite the discovery of many bioactive NPs, they often do not make it to market as d...
Flavonoids of Chromolaena odorata (L.) R.M.King & H.Rob. as potential leads for treatment against tuberculosis [0.03%]
一种菊科臭草的黄酮类化合物可能具有抗结核活性
A G Omokhua-Uyi,B Madikizela,A O Aro et al.
A G Omokhua-Uyi et al.
Tuberculosis (TB) is currently rated as the 13th leading cause of mortality and the second leading cause of death after COVID-19, and above AIDS. Existing challenges relating to the development of multidrug-resistant strains and dangerous s...
Antiviral potential of anthraquinones from Polygonaceae, Rubiaceae and Asphodelaceae: Potent candidates in the treatment of SARS-COVID-19, A comprehensive review [0.03%]
Polygonaceae、Rubiaceae 和 Asphodelaceae 植物蒽醌的抗病毒潜力：SARS-COVID-19 治疗的有力候选药物——全面综述
Augustin Ntemafack,Rahul Vikram Singh,Sabeena Ali et al.
Augustin Ntemafack et al.
Medicinal plants are being used as an alternative source of health management to cure various human ailments. The healing role is attributed to the hidden dynamic groups of various phytoconstituents, most of which have been recorded from pl...
Molecular docking of ethanol extracts of katuk leaf (Sauropus androgynus) on functional proteins of severe acute respiratory syndrome coronavirus 2 [0.03%]
猫眼草(Sauropus androgynus)叶乙醇提取物的分子对接及其对严重急性呼吸综合征冠状病毒功能蛋白的影响研究
Annisa Camellia Makati,Aghnia Nabila Ananda,Jasmine Aisyah Putri et al.
Annisa Camellia Makati et al.
The COVID-19 pandemic has become a major health crisis globally. Alternative treatment approaches include using food sources rich in flavonoid compounds, such as the leaves of katuk plant (Sauropus androgynus). The purpose of this study was...
Phytomedicines explored under in vitro and in silico studies against coronavirus: An opportunity to develop traditional medicines [0.03%]
针对冠状病毒的体外和计算机模拟研究中的植物药理：开发传统医学的机会
Yashika Gandhi,Sujeet K Mishra,Hemant Rawat et al.
Yashika Gandhi et al.
The widespread COVID-19 pandemic, caused by novel coronavirus SARS-CoV-2, has emanated as one of the most life-threatening transmissible diseases. Currently, the repurposed drugs such as remdesivir, azithromycine, chloroquine, and hydroxych...
Phytochemical profile, antioxidant, antiproliferative, and enzyme inhibition-docking analyses of Salvia ekimiana Celep & Doğan [0.03%]
Salvia ekimiana Celep & Doğan的植化素概貌及其抗氧化、抗增殖和酶抑制作用及分子对接分析
Gökçe Şeker Karatoprak,Fatih Göger,İsmail Çelik et al.
Gökçe Şeker Karatoprak et al.
Salvia ekimiana Celep & Doğan is an endemic species of Turkey. To our knowledge, the number of studies on biological activities and phytochemical profiling of this plant is quite limited. Therefore, this study aimed to analyze its activiti...
In vitro testing and computational analysis of specific phytochemicals with antiviral activities considering their possible applications against COVID-19 [0.03%]
针对COVID-19潜在应用的具抗病毒活性的植物化学成分的体外检测和计算分析
Jovana Trifunović Ristovski,Mohammed Mahbubul Matin,Ren Kong et al.
Jovana Trifunović Ristovski et al.
The purpose of this study was to investigate the reservoir of natural products against the SARS-CoV-2 virus and to identify suitable candidates in order to recommend appropriate phytotherapy. Adequately prepared 65 molecules from traditiona...
Antiviral activity of aframomum melegueta against severe acute respiratory syndrome coronaviruses type 1 and 2 [0.03%]
埃塞俄比亚胡椒对严重急性呼吸综合征冠状病毒1型和2型的抗病毒活性
Oneil Mahoney,Claudia Melo,Anthony Lockhart et al.
Oneil Mahoney et al.
Plant-based compounds with antiviral properties against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been identified in Aframomum melegueta through computational models. The seed extract have been traditionally used to ...
Identification of Papain-Like Protease inhibitors of SARS CoV-2 through HTVS, Molecular docking, MMGBSA and Molecular dynamics approach [0.03%]
通过HTVS，分子对接，MMGBSA和分子动力学方法识别SARS-CoV-2的木瓜蛋白酶样蛋白酶抑制剂
Srikanth Jupudi,Kalirajan Rajagopal,Sankaranarayanan Murugesan et al.
Srikanth Jupudi et al.
Coronaviruses (CoVs) are a large group of enveloped positive sense single-stranded RNA viruses that can cause disease to humans. These are zoonotic having potential to cause large-scale outbreaks of infections widely causing morbidity and m...
Docking-based virtual screening and identification of potential COVID-19 main protease inhibitors from brown algae [0.03%]
基于分子对接的虚拟筛选及抗SARS-CoV-2主要蛋白酶化合物的发现研究
Abdur Rauf,Umer Rashid,Anees Ahmed Khalil et al.
Abdur Rauf et al.
COVID-19 (SARS-CoV-2) is a viral disease that causes acute respiratory syndrome, which has increased the morbidity and mortality rate throughout the world. World Health Organization has declared this COVID-19 outbreak as pandemic and classi...