[The mechanism of miRNA-mediated PGR signaling pathway in regulating female reproduction] [0.03%]
[miRNA介导的PGR信号通路调控雌性生殖的机制]
Long Chen,Bao-yun Zhang,Guang-de Feng et al.
Long Chen et al.
MicroRNAs (miRNAs) are involved in several physiological processes as important post-transcriptional regulators. Progesterone (P4), an important steroid hormone, produces physiological effect through binding specific receptor progesterone r...
[Research progress in developing reporter systems for the enrichment of positive cells with targeted genome modification] [0.03%]
[靶向基因组编辑阳性细胞富集的报告系统研发进展]
Yi-chun Bai,Kun Xu,Ze-hui Wei et al.
Yi-chun Bai et al.
Targeted genome editing technology plays an important role in studies of gene function, gene therapy and transgenic breeding. Moreover, the efficiency of targeted genome editing is increased dramatically with the application of recently dev...
[From random mutagenesis to precise genome editing: the development and evolution of genome editing techniques in Drosophila] [0.03%]
从随机诱变到精准基因编辑——果蝇的基因组编辑技术的发展与演变
Fang Su,Zong-liang Huang,Ya-wen Guo et al.
Fang Su et al.
Drosophila melanogaster, an important model organism for studying life science, has contributed more to the research of genetics, developmental biology and biomedicine with the development of genome editing techniques. Drosophila genome-edi...
[Application progress of CRISPR/Cas9 genome editing technology in the treatment of HIV-1 infection] [0.03%]
CRISPR/Cas9基因编辑技术在HIV-1感染治疗中应用进展
Ying-lun Han,Qing-wei Li
Ying-lun Han
The goal of gene therapy is to introduce foreign genes into human target cells in a certain way to correct or compensate diseases caused by defective or abnormal genes. Therefore, gene therapy has great practical significance in studying th...
[The application of CRISPR/Cas9 genome editing technology in cancer research] [0.03%]
CRISPR/Cas9基因组编辑技术在癌症研究中的应用
Da-yong Wang,Ning Ma,Yang Hui et al.
Da-yong Wang et al.
The CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein-9 nuclease) genome editing technology has become more and more popular in gene editing because of its simple design and easy operation. Usi...
[Overview of patents on targeted genome editing technologies and their implications for innovation and entrepreneurship education in universities] [0.03%]
[目标基因组编辑技术专利概况及其对高校创新创业教育的意义]
Xiang-yu Fan,Yan-ping Lin,Guo-jian Liao et al.
Xiang-yu Fan et al.
Zinc finger nuclease, transcription activator-like effector nuclease, and clustered regularly interspaced short palindromic repeats/Cas9 nuclease are important targeted genome editing technologies. They have great significance in scientific...
[Single-cell detection of EGFR gene mutation in circulating tumor cells in lung cancer] [0.03%]
肺癌循环肿瘤细胞EGFR基因突变的单细胞检测
Shuai Sun,Yu-liang Deng
Shuai Sun
Circulating tumor cells (CTCs) are cells that shed from a primary tumor and enter the peripheral blood circulation. The CTCs are closely associated with tumor development and metastasis because of its high heterogeneity. However, there are ...
[Comparative genomics and evolutionary analysis of CRISPR loci in acetic acid bacteria] [0.03%]
芽孢杆菌CRISPR位点的比较基因组和进化分析
Kai Xia,Xin-le Liang,Yu-dong Li
Kai Xia
The clustered regularly interspaced short palindromic repeat (CRISPR) is a widespread adaptive immunity system that exists in most archaea and many bacteria against foreign DNA, such as phages, viruses and plasmids. In general, CRISPR syste...
Comparative Study
Yi chuan = Hereditas. 2015 Dec;37(12):1242-50. DOI:10.16288/j.yczz.15-244 2015
[Genome-wide analysis and functional prediction of the Trihelix transcription factor family in rice] [0.03%]
水稻Trihelix家族的全基因组分析及功能预测
Jian-hui Ji,Ying-jun Zhou,He-he Wu et al.
Jian-hui Ji et al.
The Trihelix transcription factor family plays an essential role in plant growth, development and stress response. However, the studies about identification and analysis of this gene family in rice on the genome-wide level have not been rep...
[Cloning and functional analysis of the cotton Trihelix transcription factor GhGT29] [0.03%]
[GhGT29基因的克隆及其功能分析]
Yue Li,Xiao-dong Liu,Yong-mei Dong et al.
Yue Li et al.
Trihelix transcription factors are important proteins involved in response to abiotic stresses in plants. Understanding the molecular mechanisms of Trihelix in cottons will lay the foundation to improve stress tolerance by gene engineering....