Genomic prediction of growth trait phenotypes in Large White pigs using a chromosome-encoded multi-head self-attention model [0.03%]
基于染色体编码的多头自注意力模型的约克夏猪生长性状表型预测
Wen-Xuan Zhou,Zhen-Jian Zhao,Dong Chen et al.
Wen-Xuan Zhou et al.
With the widespread adoption of genome sequencing technologies, predicting complex traits using genomic markers has become a key component in breeding programs. However, the high dimensionality and sparsity of genomic data, along with the c...
Multi-stage transcriptomic analysis of mouse embryonic lethality induced by homozygous knockout of the Vrtn gene [0.03%]
Vrtn基因纯合子敲除诱导的小鼠胚胎致死的多阶段转录组分析
Ya-Xin Deng,Bao-Jun Ding,Hong-Chun Li et al.
Ya-Xin Deng et al.
The Vrtn gene, a recently identified regulator of embryonic development and stem cell pluripotency, is essential for embryonic survival, as its homozygous knockout (Vrtn-/-) leads to lethality in mice at approximately embryonic day 12.5 (E1...
Identification of biomarkers for non-obstructive azoospermia based on microRNA and bioinformatics screening [0.03%]
基于微小核糖核酸和生物信息学筛选的非梗阻性无精子症生物标志物识别
Zhi-Hong Li,Miao-Qi Chen,Xiao-Jun Yuan et al.
Zhi-Hong Li et al.
MicroRNAs (miRNAs) play an important role in the occurrence of non-obstructive azoospermia (NOA). Nevertheless, there is still a lack of research on the molecular mechanisms by which miRNAs regulate target genes to mediate NOA at present. I...
Potential of SERINC2 as a biomarker in tumor prognosis and immunology: analysis from pan-cancer studies [0.03%]
泛癌分析揭示SERINC2作为肿瘤预后和免疫学生物标志物的潜力
Min Zhao,Hui-Qi Ying,Yi-Lei Yang et al.
Min Zhao et al.
Serine incorporator (SERINC) is a family of transmembrane protein involved in lipid synthesis. Among its family members, SERINC2 has been implicated in tumor pathogenesis. Pancreatic carcinoma (PAAD), a highly malignant tumor characterized ...
Xin-Yue Zhu,Kun-Long Hu,Wen-Huan Xu et al.
Xin-Yue Zhu et al.
N4-acetylcytidine (ac4C) is an emerging RNA epigenetic modification that has attracted considerable attention in the field of epitranscriptomics in recent years. This modification is widely present in tRNA, rRNA, mRNA, and various non-codin...
Chi-Zao Wang,Xue-Er Yu,Si-Yao Sang et al.
Chi-Zao Wang et al.
Understanding the genetic evolutionary history of the Daur people is academically valuable for determining how the core lineages of Mongolic-speaking and East Asian populations were formed, as the Daur represent an ancient branch of the Mon...
Guang-Fu Zou,Min Zhou,Chuan Huang
Guang-Fu Zou
Circular RNAs (circRNAs) are a class of stable single-stranded RNA molecules with diverse biological functions in eukaryotic cells. Beyond acting as direct regulatory factors, circRNAs can also indirectly participate in various physiologica...
Dong-Wei Yuan,Sheng Li
Dong-Wei Yuan
The transition from solitary ancestral cockroaches to wood-feeding cockroaches exhibiting biparental care and termites displaying sibling altruism is closely linked to their ecological specialization in feeding on nutrient-poor dead wood. H...
Analysis of STAG1 gene variants identified in a patient with intellectual disability and speech delay [0.03%]
STAG1基因变异在智力障碍和语言发育迟缓患者中的分析
Cui-Cui Jiang,Ke Wu
Cui-Cui Jiang
Autosomal dominant intellectual developmental disorder (type 47) (OMIM #617635) is associated with heterozygous variants in the STAG1 gene (OMIM*604358). The main clinical manifestations include intellectual disability, delayed language dev...
Analysis of resistance and virulence genes in anaerobic Escherichia coli from giant pandas based on whole genome sequencing [0.03%]
基于全基因组测序的圈养大熊猫来源厌氧型大肠杆菌耐药及毒力基因分析
Cheng-Xi Liu,Wen-Wen Deng,Mei Long et al.
Cheng-Xi Liu et al.
Escherichia coli is a facultative anaerobic bacterium frequently detected rate in the intestines of giant pandas. In this study, we isolated 169 anaerobic bacterial strains from fresh fecal samples of 13 giant pandas, including 13 strains o...