Chi-Zao Wang,Xue-Er Yu,Si-Yao Sang et al.
Chi-Zao Wang et al.
Understanding the genetic evolutionary history of the Daur people is academically valuable for determining how the core lineages of Mongolic-speaking and East Asian populations were formed, as the Daur represent an ancient branch of the Mon...
Guang-Fu Zou,Min Zhou,Chuan Huang
Guang-Fu Zou
Circular RNAs (circRNAs) are a class of stable single-stranded RNA molecules with diverse biological functions in eukaryotic cells. Beyond acting as direct regulatory factors, circRNAs can also indirectly participate in various physiologica...
Dong-Wei Yuan,Sheng Li
Dong-Wei Yuan
The transition from solitary ancestral cockroaches to wood-feeding cockroaches exhibiting biparental care and termites displaying sibling altruism is closely linked to their ecological specialization in feeding on nutrient-poor dead wood. H...
Analysis of STAG1 gene variants identified in a patient with intellectual disability and speech delay [0.03%]
STAG1基因变异在智力障碍和语言发育迟缓患者中的分析
Cui-Cui Jiang,Ke Wu
Cui-Cui Jiang
Autosomal dominant intellectual developmental disorder (type 47) (OMIM #617635) is associated with heterozygous variants in the STAG1 gene (OMIM*604358). The main clinical manifestations include intellectual disability, delayed language dev...
Analysis of resistance and virulence genes in anaerobic Escherichia coli from giant pandas based on whole genome sequencing [0.03%]
基于全基因组测序的圈养大熊猫来源厌氧型大肠杆菌耐药及毒力基因分析
Cheng-Xi Liu,Wen-Wen Deng,Mei Long et al.
Cheng-Xi Liu et al.
Escherichia coli is a facultative anaerobic bacterium frequently detected rate in the intestines of giant pandas. In this study, we isolated 169 anaerobic bacterial strains from fresh fecal samples of 13 giant pandas, including 13 strains o...
Mechanism of tcirg1b deficiency in disrupting central nervous system homeostasis of zebrafish [0.03%]
tcirg1b缺乏干扰斑马鱼中枢神经系统稳态的机制研究
Yu-Jie Li,Fei-Fei Li,Wen-Qing Zhang et al.
Yu-Jie Li et al.
Microglial phagocytosis is crucial for maintaining central nervous system (CNS) homeostasis, a process that depends on normal lysosomal acidification and is precisely regulated by vacuolar-type ATPase (V-ATPase). While mutations in the V-AT...
Multidimensional evidence assessment and mechanistic integration of the health effects of red and white meat [0.03%]
红肉和白肉的健康影响的证据评估及机制整合
Shan Jiang,Yu-Hang Lei,Tian-Ci Liao et al.
Shan Jiang et al.
The health effects of red and white meat have been debated for decades, and the conventional species-based binary classification fails to capture their nutritional heterogeneity and differential disease risks. This review reconstructs the m...
Shi-Tian He,Xin-Yi Zhu,Si-Huan Li et al.
Shi-Tian He et al.
Codon usage bias (CUB) refers to the non-random usage of synonymous codons during protein translation. It holds significant value for understanding species evolution, environmental adaptation, gene expression regulation, and population gene...
Progress on posttranslational modifications of ciliary tubulin and association with ciliopathies [0.03%]
纤毛病相关的纤毛微管蛋白翻译后修饰的研究进展
Zi-Tao Peng,Jiong-Chen Lin,Hai-Bo Xie
Zi-Tao Peng
Cilia are hair-like structures protruding from the surface of eukaryotic cells, composed of a microtubule-based cytoskeleton and bounded by ciliary membrane, which play a crucial role in organ development and homeostasis maintenance in orga...
Zi-Hao Wang,Zhao-Qing Yang
Zi-Hao Wang
Gene-targeted knock-in technology serves as a cornerstone tool in genetic engineering and gene therapy, designed to circumvent the unpredictability and heterogeneityassociated with conventional random integration methods. However, its pract...