[Cloning and functional analysis of the cotton Trihelix transcription factor GhGT29] [0.03%]
[GhGT29基因的克隆及其功能分析]
Yue Li,Xiao-dong Liu,Yong-mei Dong et al.
Yue Li et al.
Trihelix transcription factors are important proteins involved in response to abiotic stresses in plants. Understanding the molecular mechanisms of Trihelix in cottons will lay the foundation to improve stress tolerance by gene engineering....
[Expression analysis of green fluorescent protein in tissues and organs in α-1,3 galactosyltransferase knockout pigs] [0.03%]
α-1,3半乳糖基转移酶基因敲除猪组织器官的绿色荧光蛋白表达分析
Zhi-fang Li,Chong Feng,Hui-li Ji et al.
Zhi-fang Li et al.
The pig is an ideal source to provide organs because its organ size and physiology are similar to humans. However, an acute rejection will ensue after pig-to-human xenotransplantation. The α-1,3 galactosyltransferase gene knockout (GTKO) p...
[The application of genetic risk score in genetic studies of complex human diseases] [0.03%]
[遗传风险评分在复杂疾病遗传学研究中的应用]
Da-yan Niu,Wei-li Yan
Da-yan Niu
Complex diseases such as cardiovascular disease, type 2 diabetes, essential hypertension, asthma, obesity and cancer have spread across the globe and become the predominant cause of death. There are growing concerns over the role of genetic...
[Research progress of the bHLH transcription factors involved in genic male sterility in plants] [0.03%]
[植物雄性不育相关基因座bHLH转录因子的研究进展]
Yong-ming Liu,Ling Zhang,Jian-yu Zhou et al.
Yong-ming Liu et al.
Male sterility exists widely in the spermatophytes. It contributes to the study of plant reproductive development and can be used as an effective tool for hybrid seed production in heterosis utilization. Therefore, the study on male sterili...
[Structure and function of insulin-like growth factor acid-labile subunits in mammalian homologues] [0.03%]
[哺乳动物胰岛素样生长因子易酸性位子单元的结构和功能]
Gui-lin Li,Li-li Niu,Hai-feng Liu et al.
Gui-lin Li et al.
Insulin-like growth factors (IGFs) act as a critical signaling pathway in animals and play significant roles in body growth, development, and occurrence and progression of animal diseases. In the past, structural and functional studies of l...
Jin-wei Zhang,Yi Luo,Yu-hao Wang et al.
Jin-wei Zhang et al.
Adipose tissues play a critical role in the regulation of energy metabolism and homeostasis, and is also an important endocrine organ. Adipocyte differentiation is a complicated physiological process during which mesenchymal stem cells diff...
[Efficient genome editing in human pluripotent stem cells through CRISPR/Cas9] [0.03%]
利用CRISPR/Cas9在人多能干细胞中进行高效基因组编辑
Gai-gai Liu,Shuang Li,Yu-da Wei et al.
Gai-gai Liu et al.
The RNA-guided CRISPR (clustered regularly interspaced short palindromic repeat)-associated Cas9 nuclease has offered a new platform for genome editing with high efficiency. Here, we report the use of CRISPR/Cas9 technology to target a spec...
[Identification of C(2)M interacting proteins by yeast two-hybrid screening] [0.03%]
酵母双杂交筛选C2M结合蛋白的鉴定
Shan-shan Yue,Lai-xin Xia
Shan-shan Yue
The synaptonemal complex (SC) is a huge structure which assembles between the homologous chromosomes during meiotic prophase I. Drosophila germ cell-specific nucleoprotein C(2)M clustering at chromosomes can induce SC formation. To further ...
[Genetic basis of immune response of lymphocyte-like cells in the mucosal immune system of Lampetra japonica] [0.03%]
日本七鳃鳗粘膜免疫系统淋巴细胞样免疫细胞的遗传基础及其免疫反应特性
Xin Liu,Xue-ying Song,Xiao-ping Zhang et al.
Xin Liu et al.
In recent years, the antigen recognition mechanism based on variable lymphocyte receptors (VLRs) was found in agnathan lamprey. To illuminate the genetic basis of immune response of lymphocyte-like cells in the mucosal immune system of lamp...
[A quick and efficient method to generate hemophilia B mouse models by the CRISPR/Cas system] [0.03%]
[利用CRISPR/Cas系统快速高效地生成血友病B小鼠模型的方法]
Qi-han Wang,Cong Huai,Rui-lin Sun et al.
Qi-han Wang et al.
Hemophilia B, or the Christmas disease, is a common human disease caused by coagulation factor Ⅸ (FⅨ) deficiency. It is an X-linked recessive hereditary disease. Here we obtained FⅨ-knockout mouse strains with phenotype of hemophilia B w...