Application and progress of proximity labeling technology in the study of protein-protein interactions [0.03%]
邻近标记技术在蛋白质相互作用研究中的应用及进展
Xin-Ru Xu,Ben-Hua Qiu,Xiu-Min Yan
Xin-Ru Xu
Protein-protein interactions are essential to almost all biological processes within cells. In recent years, proximity labeling technology has emerged as a cutting-edge approach for studying protein interactions and subcellular compartment ...
Recent advances in the study of 3' untranslated regions of eukaryotic mRNAs [0.03%]
真核mRNA的3′非翻译区研究进展
Hao-Yu Luo,Xiao-Hong Yan,Fang Mu et al.
Hao-Yu Luo et al.
The 3' untranslated regions (3'UTRs) are a component of eukaryotic messenger RNAs (mRNAs) and located at their 3'-most ends. 3'UTRs play crucial roles in post-transcriptional regulation of gene expression, regulating cleavage and polyadenyl...
Harmonizing safety and development: effective conservation and sustainable utilization of China's human genetic resources [0.03%]
统筹安全与发展：加强中国人类遗传资源的有效保护和合理利用
Min Zhu,Huan-Lu Tan,Tian-Yu Zhao et al.
Min Zhu et al.
The management of human genetic resources constitutes a critical part of the national biosafety system. Its importance increasingly underscored by rapid development in biotechnology. After years of efforts, China has established a relativel...
Design and exploration of integrating bioinformatic analysis into comprehensive and exploratory epigenetic experiments [0.03%]
生物信息学分析与表观遗传实验整合的设计和探索
Sai-Nan An,Huan-Chun Yang,Shan Jiang et al.
Sai-Nan An et al.
As the most thoroughly studied epigenetic modification, DNA methylation-induced silencing of suppressor genes is closely related with the development of cancers. Bioinformatic analysis is an important research tool in the fields of life sci...
Screening and application of unstable genetically resistant strains in fission yeast [0.03%]
模式生物芽殖酵母中不稳定的基因型抗性菌株的筛选及应用研究
Lu-Feng Dan,Yi-Wen Chu,Xin-Rong Wang et al.
Lu-Feng Dan et al.
Reversible alterations at DNA sequence or epigenetic levels can result in phenotypes that are unstably inherited. The reversibility of these inheritable changes might be uniquely beneficial for adaption to possible fluctuations in environme...
Role of different Lyl1 transcripts in zebrafish primitive hematopoiesis [0.03%]
Lyl1不同转录本在斑马鱼原始造血中的作用研究
Jie-Hao Lin,Tong-Shu Yang,Wen-Qing Zhang et al.
Jie-Hao Lin et al.
Primitive hematopoiesis is a crucial process in the organism, responsible for the transportation of oxygen and nutrients during early embryonic stages and laying the foundation for the immune system. During primitive hematopoiesis, hematopo...
Analysis of regulatory mechanisms of enhancers in gastric cancer with double minute chromosomes based on bioinformatics [0.03%]
基于生物信息学的胃癌双小体重建调控机制分析增强子的调控机制
Meng-Ting An,Guan-Lin Guo,Jie Wu et al.
Meng-Ting An et al.
Gastric cancer (GC) has a high incidence and mortality rate globally. Double minutes (DMs) are extrachromosomal circular chromosomes that carry amplified oncogenes or drug resistance genes, and they are closely associated with tumorigenesis...
The role and mechanism of UFMylation, a ubiquitin-like modification, in Mycobacterium tuberculosis infection immunity [0.03%]
分枝杆菌结核分枝杆菌感染免疫中UFMylation的调控作用及其机制研究
Yi-Ran Liao,Qi-Ao Zhang,Pei-Bo Li et al.
Yi-Ran Liao et al.
Ubiquitin-fold modifier 1 (FM1) is a ubiquitin-like type I protein widely present in prokaryote and most eukaryote. UFMylaiton, mediated by UFM1, is involved in the regulation of a variety of cellular biochemical processes. Recently, the im...
Zhan-Chun Wang,Gui-Tao Zhong,Bei-Bei Zhang et al.
Zhan-Chun Wang et al.
Rice (Oryza sativa L.) is an important food crop in China. Its growth and development are threatened by rice blast, which leads to huge grain losses in severe cases. Cultivating and deploying rice varieties that contain broad-spectrum resis...
Tai-Zeng Zhou,Qiu-Yang Chen,Yi-Ting Yang et al.
Tai-Zeng Zhou et al.
MicroRNA (miRNA) is a class of single-stranded non-coding short RNA molecules about the size of 22 nt. Currently, miRNA has received the most extensive research and attention, and miRNA has been shown to be involved in the post-transcriptio...