Exploration and practice of artificial intelligence-assisted genetics experiment teaching [0.03%]
人工智能辅助遗传学实验教学的探索与实践
Xue-Ying Zhao,Yi-Ming Guan,Guang-Qi A et al.
Xue-Ying Zhao et al.
With the rapid advancement of artificial intelligence (AI) technology, exploring how to integrate AI with traditional genetic experiment courses has become a key focus of current teaching reform. Based on the conventional teaching system of...
Diagnosis and treatment analysis of a case of idiopathic hypogonadotropic hypogonadism caused by NSMF gene mutation [0.03%]
NMFS基因突变所致特发性低促性腺激素性性腺功能减退症1例诊疗分析
Shu-Yi Peng,Kai Wang,Shu-Qi Wang et al.
Shu-Yi Peng et al.
Idiopathic hypogonadotropic hypogonadism (IHH) is a rare endocrine disorder characterized by deficiency or dysfunction of endogenous gonadotropin-releasing hormone (GnRH), leading primarily to hypogonadism. Based on the presence or absence ...
Case Reports
Yi chuan = Hereditas. 2026 May;48(5):535-543. DOI:10.16288/j.yczz.25-187 2026
Prediction method for transcription factor binding sites integrating channel and spatial attention mechanisms [0.03%]
结合通道和空间注意力机制的转录因子结合位点预测方法
Ji-Hua Feng,Zhong-Xing Chen,Qi-Lin Kang et al.
Ji-Hua Feng et al.
Accurate identification of transcription factor binding sites (TFBSs) at single-nucleotide resolution remains a central challenge in deciphering gene expression regulatory networks. To improve the performance of existing computational model...
Genotype imputation improves SNP density and genetic analysis accuracy in slash pine [0.03%]
基因型填充可提高 Slash 松 SNP 密度和遗传分析准确性
Yu-Xuan Jiang,Li-Ming Bian,Shi-Liang Zhou et al.
Yu-Xuan Jiang et al.
Slash pine (Pinus elliottii) possesses an exceptionally large, repeat-rich genome, and existing low-density SNP arrays provide limited marker coverage and resolution of linkage patterns. To increase marker density for population-based genet...
Genetic polymorphism and mutation analysis of 81 autosomal STR loci in the Northern Han Chinese population [0.03%]
北方汉族人群81个autosomal STR基因座的多态性及突变分析
Hang He,Jin-Pei Zhang,Chu-Chu Zhang et al.
Hang He et al.
Examining a greater number of short tandem repeats (STRs) is essential for cases involving mutations, consanguinity, and complex kinship testing. However, previous population studies were mostly limited to fewer than 40 STRs. Therefore, thi...
Application and potential value of genotype imputation techniques in ancient DNA research [0.03%]
基因型填充技术在古DNA研究中的应用及潜在价值
Wen-Qi Wei,Da-Wei Cai
Wen-Qi Wei
Ancient DNA research plays a pivotal role in reconstructing history and understanding biological evolution. Modern genotype imputation techniques, which leverage reference panels to predict missing genotypes, have emerged as powerful tools ...
High-throughput identification methods of genomic functional variation in post-GWAS era and their application in agricultural animals [0.03%]
后GWAS时代功能性基因组变异的高通量鉴定方法及在农业动物中的应用
Xin-Yi Yin,Shou-Zhi Wang
Xin-Yi Yin
Genome-wide association study (GWAS) has identified a large number of genetic variations that are significantly associated with human diseases and animal and plant economic traits. However, the majority of these variants are located in non-...
Guang-Hao Guo,Zhi-Yong Liu
Guang-Hao Guo
Plants rely on nucleotide-binding, leucine-rich repeat (NLR) receptors to recognize effector proteins, activating immune responses. In recent years, researchers have elucidated the structures of various plant NLR resistosomes. However, the ...
Teaching design of a multi-dimensional aging experiment using the Caenorhabditis elegans model [0.03%]
基于线虫模式生物的多维度衰老实验教学设计
Li-Juan Teng,Jia-le Wang,Hui Wang et al.
Li-Juan Teng et al.
Caenorhabditis elegans (C. elegans), a classical model organism in the field of life sciences, possesses advantages including easy cultivation, a short life cycle, and a well-defined genetic background. It has been widely used in studies of...
An evolutionary perspective on the nucleocytoplasmic shuttling mechanism of duck plague virus UL54 protein [0.03%]
鸭瘟病毒UL54蛋白核质往复运输机制的进化研究
Ming-Fei Xu,Yan-Hong Yang,Qian-Qian Li et al.
Ming-Fei Xu et al.
Duck plague virus (DPV), a member of the alpha-herpesvirus, causes duck plague (DP), thereby posing a serious threat to the waterfowl industry. The DPV UL54-encoded protein shuttles between the nucleus and cytoplasm to modulate viral replic...