RE-Aging, A Functional Analysis Platform for Human RNA Editing Associated with Aging [0.03%]
RE-Aging，与人类衰老相关的RNA编辑功能分析平台
Xinyu Pan,Hui Zhang,Weiwen Huang et al.
Xinyu Pan et al.
RNA editing alters mRNA sequences and is linked to aging. We introduce RE-Aging, a platform analyzing age-related RNA editing using GTEx data (259,620 A-to-I and 30,502 C-to-U sites across 27 tissues). Features include site exploration, age...
THRAISE: An Automated and Reproducible Web Platform for RNA-seq Analysis [0.03%]
基于Web的自动化和可重复RNA序列分析平台THRAISE
Hyeon Ho Heo,Soo-Jong Um
Hyeon Ho Heo
THRAISE (Transcriptome-wide High-throughput RNA-seq Analysis Integrated System) is a highly streamlined web platform for RNA-seq analysis that requires no programming expertise. Starting from raw NCBI SRA data, it performs the entire analys...
Deficient chaperone-mediated autophagy in macrophages aggravates colitis and colitis-associated tumorigenesis in mice [0.03%]
小鼠巨噬细胞中自噬功能缺陷加重结肠炎和相关肿瘤发生
Weichun Zhu,Zehao Chen,Yunqian Gao et al.
Weichun Zhu et al.
Chaperone-mediated autophagy (CMA) is a highly selective form of autophagy re-sponsible for the degradation of specific cytosolic proteins within lysosomes. Recent research has established a significant correlation between CMA and colorecta...
Seokjun G Ha,Ji-Hoon Park,Mi-Young Kim et al.
Seokjun G Ha et al.
Western blot is an essential method that detects specific proteins using antibodies, which is one of the most widely applied techniques for protein detection. Here, we present a brief guide to western blot, following the overall procedure f...
Ionotropic receptors mediate arachidic acid perception and food avoidance behavior in Drosophila melanogaster [0.03%]
硬脂酸感受器介导果蝇对有害食物的规避行为
Roshani Nhuchhen Pradhan,Muhammad Atif,Youngseok Lee
Roshani Nhuchhen Pradhan
Chemosensory functions are essential for animals to distinguish between nutritious and harmful compounds. Fatty acids are vital dietary components, but their taste perception mechanisms remain poorly understood. In Drosophila melanogaster, ...
Ravi Shankar Goutam,Neha Kaushik,Basant Kumar et al.
Ravi Shankar Goutam et al.
The Iroquois (Iro/Irx) gene family encodes transcription factors that belong to the TALE-class homeodomain group, distinguished by a conserved Iro-box domain. Iroquois signaling is evolutionarily conserved from invertebrates to vertebrates ...
Hoyun Kwak,Wijin Jeon,Nui Ha et al.
Hoyun Kwak et al.
Egr2-dependent Mo-DCs Regulate Immunosuppressive NK cells, Promoting Neutrophil-Mediated Protective Immunity Against Acute Listeria Infection [0.03%]
Egr2依赖的莫尔根氏树突状细胞调控免疫抑制性自然杀伤细胞，促进中性粒细胞介导的急性李斯特菌感染抵抗作用
Muhammad Umer Ashraf,Myeong-Ho Kang,Yong Taik Lim et al.
Muhammad Umer Ashraf et al.
The interactions between dendritic cells (DCs) and other innate immune cells during acute bacterial infection remain poorly understood. To investigate this cross-talk, we generated CD11c-cre-mediated early growth response gene-2 knockout (E...
Sangjun Lim,Sohyun Kum,Jin Ouk Choi et al.
Sangjun Lim et al.
In this MiniResource, we outlined practical approaches for preparing murine T cells, from isolation to in vitro activation, with emphasis on reproducibility and viability. While specific experimental conditions should be tailored to individ...