Azoospermia due to a unique de novo balanced reciprocal translocation (Y;1) (q12;q25) [0.03%]
一个新的平衡的互换型染色体易位(Y;1)(q12;q25)引起的无精子症
Markus Braun-Falco,Werner Schempp,Claudia Nevinny-Stickel-Hinzpeter et al.
Markus Braun-Falco et al.
Acute adverse effects of the indenopyridine CDB-4022 on the ultrastructure of sertoli cells, spermatocytes, and spermatids in rat testes: comparison to the known sertoli cell toxicant Di-n-pentylphthalate (DPP) [0.03%]
茚并吡啶类CDB-4022急性不良效应导致大鼠睾丸支持细胞、次级精母细胞和精子细胞的超微结构损伤：与已知的支持细胞毒物DPP进行比较研究
Sheri Ann Hild,Jerry R Reel,Michael J Dykstra et al.
Sheri Ann Hild et al.
Acute effects of CDB-4022 on testicular ultrastructure were determined. Rats were treated orally with vehicle or a maximally effective single dose of CDB-4022 or Di-n-pentylphthalate (DPP). Preserved testes were processed for transmission e...
Filling time of a lamellar capillary-filling semen analysis chamber is a rapid, precise, and accurate method to assess viscosity of seminal plasma [0.03%]
利用层状毛细管填充精液分析池评估精浆粘度是一种快速、精确和准确的方法
Sanne Rijnders,Jan G M Bolscher,Joseph McDonnell et al.
Sanne Rijnders et al.
Impact of Ca2+ flux inhibitors on acrosome reaction of hamster spermatozoa [0.03%]
钙离子流抑制剂对仓鼠精子顶体反应的影响
Huai L Feng,Yi B Han,Avner Hershlag et al.
Huai L Feng et al.
Ca(2+) plays a prominent role in the regulation of critical functions of spermatozoa, such as capacitation, acrosome reaction (AR), and fertilization. While there is consensus that Ca(2+) is essential, researchers have reported conflicting ...
GM1 dynamics as a marker for membrane changes associated with the process of capacitation in murine and bovine spermatozoa [0.03%]
以GM1动力学为标记研究膜的变化与小鼠及牛精子获能过程的关系
Vimal Selvaraj,Danielle E Buttke,Atsushi Asano et al.
Vimal Selvaraj et al.
We previously showed that in live murine and bovine sperm heads, the ganglioside G(M1) localizes to the sterol-rich plasma membrane overlying the acrosome (APM). Labeling G(M1) using the pentameric cholera toxin subunit B (CTB) induced a dr...
Chronic exposure to low levels of dibromoacetic acid, a water disinfection by-product, adversely affects reproductive function in male rabbits [0.03%]
长期接触低浓度二溴乙酸，一种饮用水消毒副产物，会损害雄兔生殖功能
D N R Veeramachaneni,J S Palmer,G R Klinefelter
D N R Veeramachaneni
Four groups (minimum of 10/dose group) of male Dutch-belted rabbits were treated daily with dibromoacetic acid (DBA) via drinking water beginning in utero from gestation day 15 to adulthood; target dosages were 1, 5, and 50 mg DBA/kg body w...
Metformin restores the penile expression of nitric oxide synthase in high-fat-fed obese rats [0.03%]
二甲双胍能恢复高脂饮食肥胖大鼠阴茎一氧化氮合酶的表达
Yong-Woon Kim,So-Young Park,Jong-Yeon Kim et al.
Yong-Woon Kim et al.
Obesity is a well-known risk factor for erectile dysfunction, which is associated with reduced penile nitric oxide synthase (NOS) expression. Recently it was reported that metformin activates AMP-activated protein kinase (AMPK), which incre...
Molecular study of (TG)m(T)n polymorphisms in Iranian males with congenital bilateral absence of the vas deferens [0.03%]
伊朗无输精管症男性(TG)m(T)n多态性分子研究
Ramin Radpour,Hamid Gourabi,Mohamad Ali Sadighi Gilani et al.
Ramin Radpour et al.
Congenital bilateral absence of the vas deferens (CBAVD) is a frequent cause of obstructive azoospermia. Nearly 75% of men with CBAVD have at least 1 detectable common mutation in the cystic fibrosis transmembrane conductance regulator (CFT...
Elevated end-of-treatment serum INSL3 is associated with failure to completely suppress spermatogenesis in men receiving male hormonal contraception [0.03%]
治疗结束时血清INSL3水平升高与男性接受男性激素避孕药失败有关
John K Amory,Stephanie T Page,Bradley D Anawalt et al.
John K Amory et al.
The administration of testosterone plus a progestogen functions as a male contraceptive by inhibiting the release of pituitary gonadotropins. After 3 to 4 months of treatment, most men are azoospermic or severely oligospermic (< or =1 milli...
Biphasic effects of postnatal exposure to diethylhexylphthalate on the timing of puberty in male rats [0.03%]
双（2-乙基己基）邻苯二甲酸酯对雄性大鼠青春发育时间的双向作用效应研究
Ren-Shan Ge,Guo-Rong Chen,Qiang Dong et al.
Ren-Shan Ge et al.
Phthalate esters such as di(2-ethylhexyl)phthalate (DEHP), which are commonly found in cosmetics and in flexible plastics distributed by the food, construction, and medical products industries, have been classified as anti-androgens. High-d...