Marvin L Meistrich;Publications and Communications Committee of the American Society of Andrology;Janice Bailey,Douglas Carrell,Trevor Cooper et al.
Marvin L Meistrich;Publications and Communications Committee of the American Society of Andrology;Janice Bailey et al.
Nanomilled oral testosterone plus dutasteride effectively normalizes serum testosterone in normal men with induced hypogonadism [0.03%]
纳米球化口服睾丸激素加上度他雄胺有效使正常男性诱导性低睾酮血症患者的血液睾丸激素恢复正常水平
Stephanie T Page,William J Bremner,Richard V Clark et al.
Stephanie T Page et al.
Oral androgen development has been hampered by the rapid metabolism of orally administered testosterone (T) and low bioavailibility. The addition of the 5alpha-reductase inhibitor dutasteride (D) to oral T in oil dramatically improves conce...
Clinical Trial
Journal of andrology. 2008 Mar-Apr;29(2):222-7. DOI:10.2164/jandrol.107.002956 2008
Jason Lee,Saleh Binsaleh,Kirk Lo et al.
Jason Lee et al.
Clinical examination of the scrotum remains the most commonly used technique to diagnose varicoceles. However, scrotal anatomy (eg, thick scrotum, scarring, hydrocele) in some men may make physical examination alone unreliable. In these sit...
Assessment of Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Mycoplasma hominis, and Mycoplasma genitalium in semen and first void urine specimens of asymptomatic male partners of infertile couples [0.03%]
无症状不育夫妇男方精液和首次排尿标本中沙眼衣原体、解脲支原体、人型支原体和生殖器支原体检测分析
R Gdoura,W Kchaou,L Ammar-Keskes et al.
R Gdoura et al.
The purpose of this study was threefold: to compare semen and first void urine (FVU) specimens from asymptomatic infertile men for the detection of Chlamydia trachomatis, genital ureaplasma, and genital mycoplasma infections using in-house ...
Utility of magnetic cell separation as a molecular sperm preparation technique [0.03%]
磁性细胞分离作为分子精子处理技术的实用性研究
Tamer M Said,Ashok Agarwal,Maciej Zborowski et al.
Tamer M Said et al.
Assisted reproductive techniques (ARTs) have become the treatment of choice in many cases of infertility; however, the current success rates of these procedures remain suboptimal. Programmed cell death (apoptosis) most likely contributes to...
In vivo application of histone deacetylase inhibitor trichostatin-a impairs murine male meiosis [0.03%]
组蛋白脱乙酰酶抑制剂曲古菌素A影响小鼠雄性减数分裂
Irina Fenic,Hamid M Hossain,Violetta Sonnack et al.
Irina Fenic et al.
In vivo application of histone deacetylase (HDAC) inhibitor trichostatin-A (TSA) in mice results in male infertility. To get more insight into the mechanisms underlying this phenomenon, we performed a genome-wide expression analysis and inv...
Changes in the smooth muscle of the corpora cavernosum related to reversal of partial bladder outlet obstruction in rabbits [0.03%]
兔部分膀胱出口梗阻逆转相关的阴茎海绵体平滑肌变化
Wei-Yu Lin,Anita Mannikarottu,Paul Chichester et al.
Wei-Yu Lin et al.
Previous studies have demonstrated that partial bladder outlet obstruction (PBOO) in the rabbit induces an increase in corpus cavernosum smooth muscle (CCSM) tone, which may make it difficult for the CCSM to relax. Thus, to determine whethe...
Oral administration of tetrahydrobiopterin attenuates testicular damage by reducing nitric oxide synthase activity in a cryptorchid mouse model [0.03%]
四氢生物蝶呤通过降低一氧化氮合酶活性减轻隐睾小鼠模型的睾丸损伤
Yutaka Kondo,Tomomoto Ishikawa,Kohei Yamaguchi et al.
Yutaka Kondo et al.
Experimental cryptorchidism has been shown to induce germ cell apoptosis. Nitric oxide (NO), a ubiquitous free radical produced by NO synthases (NOSs), has been associated with apoptosis in a number of cell types. However, the regulation of...
Detection of "apoptosis-like" changes during the cryopreservation process in equine sperm [0.03%]
冷冻过程中马精子发生类似凋亡的变化的检测
C Ortega-Ferrusola,Y Sotillo-Galán,E Varela-Fernández et al.
C Ortega-Ferrusola et al.
The kinematics of the appearance of apoptotic markers was studied by flow cytometry and immunoblot assays in equine spermatozoa subjected to freezing and thawing. Caspase activity, low mitochondrial membrane potential, and increases in sper...