Signaling cascade that mediates endothelial nitric oxide synthase activation induced by atrial natriuretic peptide [0.03%]
介导心房利钠肽诱导的内皮型一氧化氮合酶活化的信号级联反应
Rosana Elesgaray,Carolina Caniffi,Daniela Rodríguez Ierace et al.
Rosana Elesgaray et al.
Atrial natriuretic peptide (ANP) induces activation of nitric oxide-synthase (NOS). Aims: to identify the isoform of NOS involved in ANP effects, to study...
Eplerenone inhibits the intracrine and extracellular actions of angiotensin II on the inward calcium current in the failing heart. On the presence of an intracrine renin angiotensin aldosterone system [0.03%]
依普利酮抑制血管紧张素Ⅱ对心力衰竭心脏细胞内钙离子电流的胞内分泌和旁分泌作用及心力衰竭心脏中存在细胞内分泌型肾素-血管紧张素-醛固酮系统
Walmor C De Mello,Yamil Gerena
Walmor C De Mello
The influence of chronic administration of eplerenone on the intracrine as well as on the extracellular action of angiotensin II (Ang II) on L-type inward calcium current was investigated in the failing heart of cardiomyopathic hamsters (TO...
Neuropeptide Y (NPY) Y2 receptors of rabbit kidney cortex are largely dimeric [0.03%]
兔肾皮质中的神经肽Y(Y2)受体主要是二聚体性质的
A M Estes,Y Y Wong,M S Parker et al.
A M Estes et al.
The neuropeptide Y (NPY) Y2 receptors and the pancreatic polypeptide Y4 receptors from rabbit kidney cortex are isolated largely as approximately 180 kDa complexes constituted of one receptor dimer and one G-protein heterotrimer, similar to...
Transient receptor potential vanilloid 1-mediated expression and secretion of endothelial cell-derived calcitonin gene-related peptide [0.03%]
瞬时受体电位香草素1介导的内皮细胞来源的降钙素基因相关肽的表达和分泌
Dan Luo,Yi-Wei Zhang,Wei-Jie Peng et al.
Dan Luo et al.
Calcitonin gene-related peptide (CGRP), the principal transmitter in sensory nerves, could also be expressed in vascular endothelium. Transient receptor potential vanilloid 1(TRPV1), which modulates the synthesis and release of CGRP in sens...
Palmiero Monteleone,Eloisa Castaldo,Mario Maj
Palmiero Monteleone
Anorexia nervosa (AN) and bulimia nervosa (BN) are psychiatric disorders characterized by abnormal eating behaviors and imbalance of energy homeostasis. Changes of both central and peripheral neuroendocrine substances involved in the modula...
Effect of insulin detemir, compared to human insulin, on 3T3-L1 adipogenesis [0.03%]
与人胰岛素相比，地特胰岛素对3T3-L1细胞向脂肪细胞分化的影响
Anja Böhm,Harald Staiger,Anita M Hennige et al.
Anja Böhm et al.
Insulin detemir (DET) represents a myristic acid (MA)-coupled insulin derivative with protracted action due to reversible albumin binding. As compared to human insulin (HI), DET provokes no or only minor body weight gain in vivo. Therefore,...
Comparative Study
Regulatory peptides. 2008 Nov 29;151(1-3):160-3. DOI:10.1016/j.regpep.2008.05.005 2008
Newly developed angiotensin II-infused experimental models in vascular biology [0.03%]
新开发的血管生物学中的血管紧张素II输注实验模型
Zhenyu Qin
Zhenyu Qin
Angiotensin II is a major vasoactive peptide in the renin-angiotensin system (RAS). In vitro evidence demonstrates that this peptide can modulate the function of various adhesion molecules, chemokines, cytokines and growth factors, and ulti...
Activation of the serotonergic 5-HT1A receptor in the paraventricular nucleus of the hypothalamus inhibits water intake and increases urinary excretion in water-deprived rats [0.03%]
激活下丘脑室旁核的五羟色胺能5-ht1a受体可抑制禁水大鼠的饮水和增加排尿
Patrícia de Souza Villa,José Vanderlei Menani,Gabriela Maria Pavan de Arruda Camargo et al.
Patrícia de Souza Villa et al.
The paraventricular nucleus (PVN) may be considered as a dynamic mosaic of chemically-specified subgroups of neurons. 5-HT(1A) is one of the prime receptors identified and there is expressed throughout all magnocellular regions of the PVN. ...
Peripheral but not central leptin treatment increases numbers of circulating NK cells, granulocytes and specific monocyte subpopulations in non-endotoxaemic lean and obese LEW-rats [0.03%]
外周而非中枢瘦素治疗增加非内毒素血症性LEW瘦型和肥胖型大鼠循环NK细胞、粒细胞和单核细胞亚群数量
Philipp Haas,Rainer H Straub,Sammy Bedoui et al.
Philipp Haas et al.
Leptin, a hormone mainly generated by adipocytes, acts centrally in the hypothalamus to regulate body weight and energy expenditure. However, there is strong evidence that leptin is also involved in cell-mediated immunity and cytokine cross...
Oxytocin stimulates glucose uptake in skeletal muscle cells through the calcium-CaMKK-AMPK pathway [0.03%]
oxytocin通过钙-CaMKK-AMPK途径刺激骨骼肌细胞葡萄糖摄取
Eun Soo Lee,Kyung-Ok Uhm,Yun Mi Lee et al.
Eun Soo Lee et al.
Oxytocin is a mammalian hormone that is released mainly after distension of the uterine cervix. In this study, we report that oxytocin stimulates intracellular release of calcium, and also activates AMPK (AMP-activated protein kinase) in C2...