Effect of obestatin on insulin, glucagon and somatostatin secretion in the perfused rat pancreas [0.03%]
OBESATIN对灌流大鼠胰腺INSULIN、GLUCAGON和SOMATOSTATIN释放的影响
Eva M Egido,Raquel Hernández,José Marco et al.
Eva M Egido et al.
Obestatin is a 23-amino acid peptide derived from preproghrelin, purified from stomach extracts and detected in peripheral plasma. In contrast to ghrelin, obestatin has been reported to inhibit appetite and gastric motility. However, these ...
Effect of neuropeptide B on feeding behavior is influenced by endogenous corticotropin-releasing factor activities [0.03%]
神经肽B对摄食行为的影响受内源性促肾上腺皮质激素释放因子活性调节
Shizu Aikawa,Makoto Ishii,Masashi Yanagisawa et al.
Shizu Aikawa et al.
Decrease in food intake is commonly seen in the mammalian response to stress. Corticotropin-releasing factor (CRF) is a factor that modulates feeding behavior under these stressful conditions. We previously reported that neuropeptide B (NPB...
Angiotensin II upregulates renin-angiotensin system in human isolated T lymphocytes [0.03%]
血管紧张素II上调人分离T淋巴细胞肾素血管紧张素系统
Mirella Coppo,Maria Boddi,Manuela Bandinelli et al.
Mirella Coppo et al.
This study was aimed at investigating the effects of Angiotensin (Ang) II stimulation on T lymphocytes mRNA expression of angiotensinogen (AGTN), angiotensin-converting enzyme (ACE) and AT1-receptor (R) and on ACE activity and Ang II conten...
Induction of angiogenesis by murine resistin: putative role of PI3-kinase and NO-dependent pathways [0.03%]
小鼠 Resistin 通过 PI3 激酶和 NO 依赖性通路诱导血管生成的作用机制研究
Stephanie A Robertson,Colin J Rae,Annette Graham
Stephanie A Robertson
Adipose tissue is a highly active endocrine organ, secreting bioactive molecules, adipokines, into the circulation. Obesity results in dysregulated adipokine secretion, contributing to pathophysiologies associated with this disorder, includ...
The importance of chromogranin A in the development and function of endocrine pancreas [0.03%]
胰石素A在内分泌胰腺发育和功能中的作用
G M Portela-Gomes,J R Gayen,L Grimelius et al.
G M Portela-Gomes et al.
Background: Chromogranin (Cg) A is expressed in neuroendocrine and neuronal tissues. It is involved in the generation of secretory granules and is cleaved to form biologically active peptides. Targeted ablation of the Chg...
A Schrott-Fischer,M Bitsche,C Humpel et al.
A Schrott-Fischer et al.
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder which primarily affects motor neurons. Eight cases of ALS and seven control cases were studied with semiquantitative immunocytochemistry for chromogranin A, chromogranin B ...
Triiodothyronine (T3) stimulates food intake via enhanced hypothalamic AMP-activated kinase activity [0.03%]
三碘甲状腺原氨酸(T3)通过增强下丘脑AMP活化蛋白激酶活性来刺激摄食行为
Shinya Ishii,Jun Kamegai,Hideki Tamura et al.
Shinya Ishii et al.
Thyroid hormone regulates food intake. We previously reported that rats with triiodothyronine (T3)-induced thyrotoxicosis display hyperphagia associated with suppressed circulating leptin levels, increased hypothalamic neuropeptide Y (NPY) ...
Expression of PCSK1 (PC1/3), PCSK2 (PC2) and PCSK3 (furin) in mouse small intestine [0.03%]
小鼠小肠中PCSK1(PC1/3)、PCSK2(PC2)和PCSK3(furin)的表达
Jeffrey Gagnon,Janice Mayne,Majambu Mbikay et al.
Jeffrey Gagnon et al.
The family of serine proteases known as the proprotein convertases subtilisin/kexin type (PCSK) is responsible for the cleavage and maturation of many precursor hormones. Over its three successive regions, the duodenum, the jejunum and the ...
PACAP38 protects rat cortical neurons against the neurotoxicity evoked by sodium nitroprusside and thrombin [0.03%]
Alma Sanchez,Haripriya Vittal Rao,Paula Grammas
Alma Sanchez
Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 is a multifunctional anti-inflammatory and anti-apoptotic neuropeptide widely distributed in the nervous system. The objective of this study is to determine whether PACAP38 is ne...
Effect of exenatide on gastric emptying and relationship to postprandial glycemia in type 2 diabetes [0.03%]
Helle Linnebjerg,Soomin Park,Prajakti A Kothare et al.
Helle Linnebjerg et al.
Objectives: To evaluate the effect of exenatide on gastric emptying (GE) in type 2 diabetes using scintigraphy. Methods: Seventeen subj...
Randomized Controlled Trial
Regulatory peptides. 2008 Nov 29;151(1-3):123-9. DOI:10.1016/j.regpep.2008.07.003 2008