Association between the AGTR1 polymorphism +1166A>C and serum levels of high-sensitivity C-reactive protein [0.03%]
血管紧张素受体1基因+1166位点多态性与高敏C反应蛋白血症的相关性研究
Petra Suchankova,Susanne Henningsson,Marie Olsson et al.
Petra Suchankova et al.
Genetic factors have been shown to influence high-sensitivity C-reactive protein (hsCRP) levels, however, which genes that are involved in this process remains to be clarified. The renin-angiotensin system (RAS) is of importance for the reg...
Weight-dependent differential contribution of insulin secretion and clearance to hyperinsulinemia of obesity [0.03%]
肥胖状态下体重依赖性的胰岛素分泌和清除对高胰岛血症的贡献差异性分析研究
Johannes Erdmann,Martina Mayr,Ulrich Oppel et al.
Johannes Erdmann et al.
Obesity is associated with insulin resistance and the resulting hyperinsulinemia has been attributed to an increase of insulin secretion and a reduction of insulin clearance. The present study was intended to further characterize the relati...
The effects of chronic low-dose capsaicin treatment on substance P levels [0.03%]
慢性低剂量辣椒素处理对物质P水平的影响
Nuray Erin,Berrin Zik,Münevver Sarigül et al.
Nuray Erin et al.
Capsaicin, the pungent ingredient of red pepper, is consumed in varying amounts by many ethnic groups. It serves both therapeutically and as a specific tool to investigate sensory neurons. Although effects of high capsaicin doses are well-e...
Nuray Erin,Ozkan Ulusoy
Nuray Erin
Substance P (SP) originally found as a neuropeptide in capsaicin-sensitive sensory neurons, had more recently been identified in non-neuronal cells, especially under pathological conditions. Neuronal and non-neuronal SP may perform distinct...
Release of regulatory gut peptides somatostatin, neurotensin and vasoactive intestinal peptide by acid and hyperosmolal solutions in the intestine in conscious rats [0.03%]
清醒大鼠肠道内酸性溶液和高渗溶液诱发肠释放生长抑素、神经紧张素及血管活性肠肽的研究
T Rudholm,B Wallin,E Theodorsson et al.
T Rudholm et al.
The impact of exposure of the intestinal mucosa to acid and hyperosmolal solutions on the release of the inhibitory gut peptides somatostatin (SOM), neurotensin (NT) and vasoactive intestinal peptide (VIP) was studied in conscious rats duri...
Comparative Study
Regulatory peptides. 2009 Jan 8;152(1-3):8-12. DOI:10.1016/j.regpep.2008.10.002 2009
The non-peptide kinin receptor antagonists FR 173657 and SSR 240612: preclinical evidence for the treatment of skin inflammation [0.03%]
非肽类激肽受体拮抗剂FR173657和SSR240612：治疗皮肤炎症的药理证据
Evelise Fernandes Pietrovski,Michel Fleith Otuki,Domenico Regoli et al.
Evelise Fernandes Pietrovski et al.
Peptide and non-peptide kinin receptor antagonists were evaluated in cutaneous inflammation models in mice. Topical and i.p. application of kinin B(1) and B(2) receptor antagonists caused a significant inhibition of the capsaicin-induced cu...
Urotensin II is an autocrine/paracrine growth factor for aortic adventitia of rat [0.03%]
尿皮素Ⅱ为大鼠主动脉外膜的自分泌/旁分泌生长因子
Yonggang Zhang,Yuguang Li,Ruihong Wei et al.
Yonggang Zhang et al.
Urotensin II (UII) is a potent vasoconstrictive peptide; however, its significance in vascular adventitia has not been clearly elucidated. In this study, rat aortic adventitia showed mRNA expression and immunoreactivity of UII and its recep...
Intrapulmonary potential of polyethylene glycol-modified glucagon-like peptide-1s as a type 2 anti-diabetic agent [0.03%]
聚乙二醇修饰的胰高血糖素样肽-1作为第二型抗糖尿病药物的肺给药潜力
Kang Choon Lee,Su Young Chae,Tae Hyung Kim et al.
Kang Choon Lee et al.
The pulmonary delivery of anti-diabetic peptide drugs can improve diabetic patient compliance. In this study, we tried to improve the pulmonary pharmacokinetic properties of glucagon-like peptide-1(7-36) (GLP-1) using a PEGylation approach....
Human adrenomedullin combined with human adrenomedullin binding protein-1 is protective in gut ischemia and reperfusion injury in the rat [0.03%]
人肾上腺髓质素与人肾上腺髓质素结合蛋白-1在大鼠肠道缺血再灌注损伤中的保护作用
Fangming Zhang,Rongqian Wu,Mian Zhou et al.
Fangming Zhang et al.
Previous studies have demonstrated that co-administration of rat adrenomedullin (AM) and human AM binding protein-1 (AMBP-1) has various beneficial effects following adverse circulatory conditions. In order to reduce rat proteins to elicit ...
Comparison of the effects of peripherally administered kisspeptins [0.03%]
外周给药的kisspeptin类激素的效果比较研究
Jens D Mikkelsen,Agnete H Bentsen,Laura Ansel et al.
Jens D Mikkelsen et al.
Kisspeptins are structurally closely related peptides derived from the Kiss1 gene that have been demonstrated to stimulate the hypothalamo-pituitary gonadal axis. The natural peptide products derived from post-translational processing of th...
Comparative Study
Regulatory peptides. 2009 Jan 8;152(1-3):95-100. DOI:10.1016/j.regpep.2008.10.001 2009