Hans-Rudolf Berthoud
Hans-Rudolf Berthoud
Food interacts with sensors all along the alimentary canal to provide the brain with information regarding its composition, energy content, and beneficial effect. Vagal afferents innervating the gastrointestinal tract, pancreas, and liver p...
Significance of the adrenergic system in the regulation of vasopressin secretion in rat neurohypophyseal tissue cultures [0.03%]
肾上腺素系统调节大鼠神经垂体组织中血管加压素分泌的意义
M Radács,M Gálfi,Gy Nagyéri et al.
M Radács et al.
The effects of adrenaline (A) and noradrenaline (NA) on vasopressin (VP) secretion were studied in 13-14-day cultures of isolated rat neurohypophyseal (NH) tissue. The VP contents of the supernatant media were determined by radioimmunoassay...
Effect of protein, fat, carbohydrate and fibre on gastrointestinal peptide release in humans [0.03%]
蛋白质、脂肪、碳水化合物和纤维对人胃肠激素释放的影响
L J Karhunen,K R Juvonen,A Huotari et al.
L J Karhunen et al.
Short-term regulation of food intake controls what, when and how much we eat within a single day or a meal. This regulation results from an integrated response to neural and humoral signals that originate from the brain, gastrointestinal (G...
Edith Mensah-Osman,Ed Labut,Yana Zavros et al.
Edith Mensah-Osman et al.
Gastrin is secreted from neuroendocrine cells residing in the adult antrum called G cells, but constitutively low levels are also expressed in the duodenum and fetal pancreas. Gastrin normally regulates gastric acid secretion by stimulating...
Gastric emptying in response to IAPP and CCK in rats with subdiaphragmatic afferent vagotomy [0.03%]
十二指肠迷走神经切除大鼠的IAPP和CCK促胃排空作用研究
Johan Wickbom,Margery K Herrington,Johan Permert et al.
Johan Wickbom et al.
In the subdiaphragmatic vagal deafferentation procedure (SDA), the afferent fibers of the vagus are surgically severed unilaterally where they enter the brain stem. The technique includes a subdiaphragmal truncal vagotomy performed on the c...
Cholecystokinin-58 and cholecystokinin-8 produce similar but not identical activations of myenteric plexus and dorsal vagal complex [0.03%]
胆囊收缩素-58和胆囊收缩素-8对肌间神经丛和迷走神经背侧复合体的激活作用类似但不完全相同
Marvis S Cooper,Joseph R Reeve Jr,Shannon J Raboin et al.
Marvis S Cooper et al.
The enteric nervous system (ENS: myenteric and submucosal plexuses) of the gastrointestinal tract may have a role in the reduction of food intake by cholecystokinin (CCK). Exogenous cholecystokinin-8 (CCK-8) activates the myenteric plexus a...
Adaptive upregulation of gastric and hypothalamic ghrelin receptors and increased plasma ghrelin in a model of cancer chemotherapy-induced dyspepsia [0.03%]
化疗诱发的消化不良模型中胃和下丘脑的ghrelin受体上调及血浆ghrelin水平升高
N M Malik,G B T Moore,R Kaur et al.
N M Malik et al.
Chemotherapy treatment can lead to delayed gastric emptying, early satiety, anorexia, nausea and vomiting, described collectively as the cancer-associated dyspepsia syndrome (CADS). Administration of ghrelin (GHRL), an endogenous orexigenic...
Atrial natriuretic factor intracellular signaling in the rat submandibular gland [0.03%]
关于心房钠尿肽在大鼠颌下腺细胞内信号转导的研究
María S Ventimiglia,Myrian R Rodríguez,Juan C Elverdín et al.
María S Ventimiglia et al.
We previously reported that intravenously administered atrial natriuretic factor (ANF) induced no salivation but enhanced agonist-evoked secretion in submandibular glands. The gene expression of ANF and natriuretic peptide receptors (NPR) w...
The effects of age on uptake, serum half-life and bioavailability of mouse [D-Leu-4]OB3, a synthetic peptide amide with leptin-like activity, in male C57BL/6J mice [0.03%]
年龄对小鼠[D-Leu-4]OB3摄取、血清半衰期和生物利用度的影响：一种具有类似瘦素活性的合成肽胺在雄性C57BL/6J小鼠中的作用
Daniel W Lee,Matthew C Leinung,Patricia Grasso
Daniel W Lee
We have previously shown that the activity of a synthetic peptide amide corresponding to amino acid residues 116-130 of mouse leptin is contained in a restricted sequence at the amino terminus of the peptide, between residues 116 and 122 (S...
Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice [0.03%]
胃泌素受体敲除小鼠的改善胰岛素敏感性和代谢灵活性
Kenneth A Longo,Soratree Charoenthongtrakul,Derek J Giuliana et al.
Kenneth A Longo et al.
Stimulation of the ghrelin receptor (GhrR) by ghrelin results in a variety of metabolic changes including increased food intake, fat storage and insulin resistance. Loss of ghrelin signaling is protective against diet-induced obesity, sugge...
Comparative Study
Regulatory peptides. 2008 Oct 9;150(1-3):55-61. DOI:10.1016/j.regpep.2008.03.011 2008