Majood Haddad,Alex Frickenstein,Stefan Wilhelm
Majood Haddad
Understanding nanoparticle-cell interactions at single-nanoparticle and single-cell resolutions is crucial to improving the design of next-generation nanoparticles for safer, more effective, and more efficient applications in nanomedicine. ...
Recent Review on Selected Xenobiotics and Their Impacts on Gut Microbiome and Metabolome [0.03%]
几种外来物质及其对肠道微生态和代谢的影响研究进展
Yan Jin,Jinhua Chi,Kaelene LoMonaco et al.
Yan Jin et al.
As it is well known, the gut is one of the primary sites in any host for xenobiotics, and the many microbial metabolites responsible for the interactions between the gut microbiome and the host. However, there is a growing concern about the...
Single-cell omic molecular profiling using capillary electrophoresis-mass spectrometry [0.03%]
基于毛细管电泳-质谱的单细胞组学分子分析技术
Ketki Bagwe,Noah Gould,Kendall R Johnson et al.
Ketki Bagwe et al.
Tissues and other cell populations are highly heterogeneous at the cellular level, owing to differences in expression and modifications of proteins, polynucleotides, metabolites, and lipids. The ability to assess this heterogeneity is cruci...
Recent advances in RNA sample preparation techniques for the detection of SARS-CoV-2 in saliva and gargle [0.03%]
近期用于检测唾液和漱口样本中SARS-CoV-2的RNA样品制备技术进展
Yanming Liu,Teresa Kumblathan,Jeffrey Tao et al.
Yanming Liu et al.
Molecular detection of SARS-CoV-2 in gargle and saliva complements the standard analysis of nasopharyngeal swabs (NPS) specimens. Although gargle and saliva specimens can be readily obtained non-invasively, appropriate collection and proces...
Xiaofeng Wu,Yi-Kai Liu,Anton B Iliuk et al.
Xiaofeng Wu et al.
Protein phosphorylation is an essential post-translational modification that regulates many aspects of cellular physiology, and dysregulation of pivotal phosphorylation events is often responsible for disease onset and progression. Clinical...
High-Throughput Mass Spectrometry Imaging of Biological Systems: Current Approaches and Future Directions [0.03%]
高通量质谱成像技术在生物学系统中的应用：当前策略及未来方向
Li-Xue Jiang,Manxi Yang,Syeda Nazifa Wali et al.
Li-Xue Jiang et al.
In the past two decades, the power of mass spectrometry imaging (MSI) for the label free spatial mapping of molecules in biological systems has been substantially enhanced by the development of approaches for imaging with high spatial resol...
Past, current, and future roles of 3D printing in the development of capillary electrophoresis systems [0.03%]
三维打印在毛细管电泳系统开发中的过去、现在和未来的角色
Joule E Esene,Parker R Nasman,Yesman Akuoko et al.
Joule E Esene et al.
3D printing, an additive manufacturing technology, has made significant inroads into improving systems for bioanalysis in recent years. This approach is particularly powerful due to the ease and flexibility in rapidly creating novel and com...
Next-generation molecular diagnostics: Leveraging digital technologies to enhance multiplexing in real-time PCR [0.03%]
下一代分子诊断：利用数字技术增强实时PCR的多重检测能力
Louis Kreitmann,Luca Miglietta,Ke Xu et al.
Louis Kreitmann et al.
Real-time polymerase chain reaction (qPCR) enables accurate detection and quantification of nucleic acids and has become a fundamental tool in biological sciences, bioengineering and medicine. By combining multiple primer sets in one reacti...
CRISPR techniques and potential for the detection and discrimination of SARS-CoV-2 variants of concern [0.03%]
CRISPR技术在SARS-CoV-2关切变异株检测与鉴别中的应用潜力
Huyan Xiao,Jianyu Hu,Camille Huang et al.
Huyan Xiao et al.
The continuing evolution of the SARS-CoV-2 virus has led to the emergence of many variants, including variants of concern (VOCs). CRISPR-Cas systems have been used to develop techniques for the detection of variants. These techniques have f...
Fluorescent detection of emerging virus based on nanoparticles: From synthesis to application [0.03%]
基于纳米粒子的新兴病毒荧光检测法：从合成到应用
Qian Xu,Fangbin Xiao,Hengyi Xu
Qian Xu
The spread of COVID-19 has caused huge economic losses and irreversible social impact. Therefore, to successfully prevent the spread of the virus and solve public health problems, it is urgent to develop detection methods with high sensitiv...